Q11203 (SIAT6_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
EC=2.4.99.6

Alternative name(s):
Beta-galactoside alpha-2,3-sialyltransferase 3
Short name=Alpha 2,3-ST 3
Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase
N-acetyllactosaminide alpha-2,3-sialyltransferase
ST3Gal III
Short name=ST3GalIII
ST3N
Sialyltransferase 6

Gene names

Name:	ST3GAL3
Synonyms:	SIAT6

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc By similarity.
Catalytic activity	CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note: Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Tissue specificity	Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
Post-translational modification	The soluble form derives from the membrane form by proteolytic processing.
Involvement in disease	Mental retardation, autosomal recessive 12 (MRT12) [MIM:611090]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.7
Sequence similarities	Belongs to the glycosyltransferase 29 family.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane Secreted
Coding sequence diversity	Alternative splicing
Disease	Disease mutation Mental retardation
Domain	Signal-anchor Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	O-glycan processing Traceable author statement. Source: Reactome keratan sulfate biosynthetic process Traceable author statement. Source: Reactome post-translational protein modification Traceable author statement. Source: Reactome
Cellular_component	Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell Golgi membrane Traceable author statement. Source: Reactome extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell integral to Golgi membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	N-acetyllactosaminide alpha-2,3-sialyltransferase activity Traceable author statement Ref.1. Source: ProtInc beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Alternative products

This entry describes 26 isoforms produced by alternative splicing. [Align] [Select]

Isoform B1 (identifier: Q11203-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform A1 (identifier: Q11203-2)

The sequence of this isoform differs from the canonical sequence as follows:
     40-40: N → SKYSHSSSPQEKPVAD

Isoform A7 (identifier: Q11203-3)

The sequence of this isoform differs from the canonical sequence as follows:
     40-40: N → SKYSHSSSPQEKPVAD
     133-155: DNLIKAILSVTKEYRLTPALDSL → VLDAQYPARERVSAEAGESSRHH
     156-375: Missing.

Isoform A8 (identifier: Q11203-4)

The sequence of this isoform differs from the canonical sequence as follows:
     40-40: N → SKYSHSSSPQEKPVAD
     70-70: L → LSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFLKLPR

Isoform B1-90 (identifier: Q11203-5)

The sequence of this isoform differs from the canonical sequence as follows:
     249-278: Missing.

Isoform B1+32 (identifier: Q11203-6)

The sequence of this isoform differs from the canonical sequence as follows:
     187-189: LNS → PRL
     190-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform B3 (identifier: Q11203-7)

The sequence of this isoform differs from the canonical sequence as follows:
     71-101: Missing.

Isoform B4 (identifier: Q11203-8)

The sequence of this isoform differs from the canonical sequence as follows:
     249-346: Missing.

Isoform B4+173 (identifier: Q11203-9)

The sequence of this isoform differs from the canonical sequence as follows:
     102-115: FSKPAPMFLDDSFR → EKVRTFMAWLAWYG
     116-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform B5+26 (identifier: Q11203-10)

The sequence of this isoform differs from the canonical sequence as follows:
     187-375: Missing.

Isoform B5+173 (identifier: Q11203-11)

The sequence of this isoform differs from the canonical sequence as follows:
     102-121: FSKPAPMFLDDSFRKWARIR → AKRNGAWRQKHIQAYVLRQR
     122-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform B7 (identifier: Q11203-12)

The sequence of this isoform differs from the canonical sequence as follows:
     133-155: DNLIKAILSVTKEYRLTPALDSL → VLDAQYPARERVSAEAGESSRHH
     156-375: Missing.

Isoform B8 (identifier: Q11203-13)

The sequence of this isoform differs from the canonical sequence as follows:
     70-70: L → LSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFLKLPR

Isoform B10 (identifier: Q11203-14)

The sequence of this isoform differs from the canonical sequence as follows:
     133-151: DNLIKAILSVTKEYRLTPA → ECIGWLLEICGHSSAQGAP
     152-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform C1 (identifier: Q11203-15)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K

Isoform C4 (identifier: Q11203-16)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     249-346: Missing.

Isoform C5 (identifier: Q11203-17)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     186-202: RLNSAPVKGFEKDVGSK → SPGRTISSERKSFCGSW
     203-375: Missing.

Isoform C7 (identifier: Q11203-18)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     133-155: DNLIKAILSVTKEYRLTPALDSL → VLDAQYPARERVSAEAGESSRHH
     156-375: Missing.

Isoform C8 (identifier: Q11203-19)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     70-70: L → LSPRTLCTVVFGLDCILESPGEPKKLLMPASHPLEILKSLSEDTAFALGFLKLPR

Isoform C9 (identifier: Q11203-20)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     187-244: LNSAPVKGFE...DFKWLKYIVY → VHRMASGNLW...GTSLPLAVWQ
     245-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Isoform C11 (identifier: Q11203-21)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     71-101: Missing.
     249-346: Missing.

Isoform C12 (identifier: Q11203-22)

The sequence of this isoform differs from the canonical sequence as follows:
     40-56: NSVVLSFDSAGQTLGSE → K
     102-117: FSKPAPMFLDDSFRKW → PGRTISSERKSFCGSW
     118-375: Missing.

Isoform D2+26 (identifier: Q11203-23)

The sequence of this isoform differs from the canonical sequence as follows:
     40-55: NSVVLSFDSAGQTLGS → SKYSHSSSPQEKPVA
     187-375: Missing.

Isoform D5 (identifier: Q11203-24)

The sequence of this isoform differs from the canonical sequence as follows:
     40-55: NSVVLSFDSAGQTLGS → SKYSHSSSPQEKPVA
     186-202: RLNSAPVKGFEKDVGSK → SPGRTISSERKSFCGSW
     203-375: Missing.

Isoform E1 (identifier: Q11203-25)

The sequence of this isoform differs from the canonical sequence as follows:
     40-43: NSVV → SLLN
     44-375: Missing.

Isoform E3+32 (identifier: Q11203-26)

The sequence of this isoform differs from the canonical sequence as follows:
     40-73: NSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAE → SSPSQHPCSWMTPFASGLESGSSCRLLGSKVKTI
     74-375: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 375	375	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase		PRO_0000149266
Regions
	Topological domain	1 – 8	8	Cytoplasmic Potential
	Transmembrane	9 – 28	20	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	29 – 375	347	Lumenal Potential
Amino acid modifications
	Glycosylation	80	1	N-linked (GlcNAc...) Potential
	Glycosylation	171	1	N-linked (GlcNAc...) Potential
	Disulfide bond	160 ↔ 314		By similarity
Natural variations
	Alternative sequence	40 – 73	34	NSVVL…KLPAE → SSPSQHPCSWMTPFASGLES GSSCRLLGSKVKTI in isoform E3+32.		VSP_010595
	Alternative sequence	40 – 56	17	NSVVL…TLGSE → K in isoform C1, isoform C4, isoform C5, isoform C7, isoform C8, isoform C9, isoform C11 and isoform C12.		VSP_010594
	Alternative sequence	40 – 55	16	NSVVL…QTLGS → SKYSHSSSPQEKPVA in isoform D5 and isoform D2+26.		VSP_010593
	Alternative sequence	40 – 43	4	NSVV → SLLN in isoform E1.		VSP_010592
	Alternative sequence	40	1	N → SKYSHSSSPQEKPVAD in isoform A1, isoform A7 and isoform A8.		VSP_010591
	Alternative sequence	44 – 375	332	Missing in isoform E1.		VSP_010596
	Alternative sequence	70	1	L → LSPRTLCTVVFGLDCILESP GEPKKLLMPASHPLEILKSL SEDTAFALGFLKLPR in isoform A8, isoform B8 and isoform C8.		VSP_010597
	Alternative sequence	71 – 101	31	Missing in isoform B3 and isoform C11.		VSP_010598
	Alternative sequence	74 – 375	302	Missing in isoform E3+32.		VSP_010599
	Alternative sequence	102 – 121	20	FSKPA…WARIR → AKRNGAWRQKHIQAYVLRQR in isoform B5+173.		VSP_010602
	Alternative sequence	102 – 117	16	FSKPA…SFRKW → PGRTISSERKSFCGSW in isoform C12.		VSP_010601
	Alternative sequence	102 – 115	14	FSKPA…DDSFR → EKVRTFMAWLAWYG in isoform B4+173.		VSP_010600
	Alternative sequence	116 – 375	260	Missing in isoform B4+173.		VSP_010603
	Alternative sequence	118 – 375	258	Missing in isoform C12.		VSP_010604
	Alternative sequence	122 – 375	254	Missing in isoform B5+173.		VSP_010605
	Alternative sequence	133 – 155	23	DNLIK…ALDSL → VLDAQYPARERVSAEAGESS RHH in isoform A7, isoform B7 and isoform C7.		VSP_010607
	Alternative sequence	133 – 151	19	DNLIK…RLTPA → ECIGWLLEICGHSSAQGAP in isoform B10.		VSP_010606
	Alternative sequence	152 – 375	224	Missing in isoform B10.		VSP_010608
	Alternative sequence	156 – 375	220	Missing in isoform A7, isoform B7 and isoform C7.		VSP_010609
	Alternative sequence	186 – 202	17	RLNSA…DVGSK → SPGRTISSERKSFCGSW in isoform C5 and isoform D5.		VSP_010610
	Alternative sequence	187 – 375	189	Missing in isoform B5+26 and isoform D2+26.		VSP_010613
	Alternative sequence	187 – 244	58	LNSAP…KYIVY → VHRMASGNLWPLECPRSPLR FESSTHISSRRPPSPSLACP STMASWAGGTSLPLAVWQ in isoform C9.		VSP_010612
	Alternative sequence	187 – 189	3	LNS → PRL in isoform B1+32.		VSP_010611
	Alternative sequence	190 – 375	186	Missing in isoform B1+32.		VSP_010614
	Alternative sequence	203 – 375	173	Missing in isoform C5 and isoform D5.		VSP_010615
	Alternative sequence	245 – 375	131	Missing in isoform C9.		VSP_010616
	Alternative sequence	249 – 346	98	Missing in isoform B4, isoform C4 and isoform C11.		VSP_010618
	Alternative sequence	249 – 278	30	Missing in isoform B1-90.		VSP_010617
	Natural variant	13	1	A → D in MRT12; most of the mutant protein is improperly localized to the endoplasmic reticulum preventing the protein from interacting with its substrates in the Golgi and resulting in a loss-of-function. Ref.7		VAR_066594
	Natural variant	370	1	D → Y in MRT12; the mutant protein is improperly localized to the endoplasmic reticulum preventing the protein from interacting with its substrates in the Golgi and resulting in a loss-of-function; shows a complete lack of enzyme activity; secretion of the mutant protein is dramatically reduced compared to wild-type. Ref.7		VAR_066595
Experimental info
	Sequence conflict	38	1	D → N in AAO38806. Ref.3
	Sequence conflict	94	1	L → S in AAO38810. Ref.3
	Sequence conflict	123	1	F → L in AAO38810. Ref.3
	Sequence conflict	351	1	N → S in AAO38811. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform B1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: C9B7B61AD580EC2E	FASTA	375	42,171
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 160 170 180 REFVPPFGIK GQDNLIKAIL SVTKEYRLTP ALDSLRCRRC IIVGNGGVLA NKSLGSRIDD 190 200 210 220 230 240 YDIVVRLNSA PVKGFEKDVG SKTTLRITYP EGAMQRPEQY ERDSLFVLAG FKWQDFKWLK 250 260 270 280 290 300 YIVYKERVSA SDGFWKSVAT RVPKEPPEIR ILNPYFIQEA AFTLIGLPFN NGLMGRGNIP 310 320 330 340 350 360 TLGSVAVTMA LHGCDEVAVA GFGYDMSTPN APLHYYETVR MAAIKESWTH NIQREKEFLR 370 KLVKARVITD LSSGI
	Isoform A1 [UniParc]. Checksum: DCBE59B0BFF74B3A	FASTA	390	43,786
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVADSVVLS 70 80 90 100 110 120 FDSAGQTLGS EYDRLGFLLN LDSKLPAELA TKYANFSEGA CKPGYASALM TAIFPRFSKP 130 140 150 160 170 180 APMFLDDSFR KWARIREFVP PFGIKGQDNL IKAILSVTKE YRLTPALDSL RCRRCIIVGN 190 200 210 220 230 240 GGVLANKSLG SRIDDYDIVV RLNSAPVKGF EKDVGSKTTL RITYPEGAMQ RPEQYERDSL 250 260 270 280 290 300 FVLAGFKWQD FKWLKYIVYK ERVSASDGFW KSVATRVPKE PPEIRILNPY FIQEAAFTLI 310 320 330 340 350 360 GLPFNNGLMG RGNIPTLGSV AVTMALHGCD EVAVAGFGYD MSTPNAPLHY YETVRMAAIK 370 380 390 ESWTHNIQRE KEFLRKLVKA RVITDLSSGI
	Isoform A7 [UniParc]. Checksum: 73BE2801C40F2F9B	FASTA	170	19,043
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVADSVVLS 70 80 90 100 110 120 FDSAGQTLGS EYDRLGFLLN LDSKLPAELA TKYANFSEGA CKPGYASALM TAIFPRFSKP 130 140 150 160 170 APMFLDDSFR KWARIREFVP PFGIKGQVLD AQYPARERVS AEAGESSRHH
	Isoform A8 [UniParc]. Checksum: EDFBE742E527970E	FASTA	444	49,649
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVADSVVLS 70 80 90 100 110 120 FDSAGQTLGS EYDRLGFLLN LDSKLSPRTL CTVVFGLDCI LESPGEPKKL LMPASHPLEI 130 140 150 160 170 180 LKSLSEDTAF ALGFLKLPRP AELATKYANF SEGACKPGYA SALMTAIFPR FSKPAPMFLD 190 200 210 220 230 240 DSFRKWARIR EFVPPFGIKG QDNLIKAILS VTKEYRLTPA LDSLRCRRCI IVGNGGVLAN 250 260 270 280 290 300 KSLGSRIDDY DIVVRLNSAP VKGFEKDVGS KTTLRITYPE GAMQRPEQYE RDSLFVLAGF 310 320 330 340 350 360 KWQDFKWLKY IVYKERVSAS DGFWKSVATR VPKEPPEIRI LNPYFIQEAA FTLIGLPFNN 370 380 390 400 410 420 GLMGRGNIPT LGSVAVTMAL HGCDEVAVAG FGYDMSTPNA PLHYYETVRM AAIKESWTHN 430 440 IQREKEFLRK LVKARVITDL SSGI
	Isoform B1-90 [UniParc]. Checksum: 0AA0ED4823826782	FASTA	345	38,742
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 160 170 180 REFVPPFGIK GQDNLIKAIL SVTKEYRLTP ALDSLRCRRC IIVGNGGVLA NKSLGSRIDD 190 200 210 220 230 240 YDIVVRLNSA PVKGFEKDVG SKTTLRITYP EGAMQRPEQY ERDSLFVLAG FKWQDFKWLK 250 260 270 280 290 300 YIVYKERVEA AFTLIGLPFN NGLMGRGNIP TLGSVAVTMA LHGCDEVAVA GFGYDMSTPN 310 320 330 340 APLHYYETVR MAAIKESWTH NIQREKEFLR KLVKARVITD LSSGI
	Isoform B1+32 [UniParc]. Checksum: 73A783656B89AAF0	FASTA	189	21,204
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 160 170 180 REFVPPFGIK GQDNLIKAIL SVTKEYRLTP ALDSLRCRRC IIVGNGGVLA NKSLGSRIDD YDIVVRPRL
	Isoform B3 [UniParc]. Checksum: 9BA97BCA7FA29E8A	FASTA	344	38,912
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL FSKPAPMFLD DSFRKWARIR EFVPPFGIKG QDNLIKAILS VTKEYRLTPA 130 140 150 160 170 180 LDSLRCRRCI IVGNGGVLAN KSLGSRIDDY DIVVRLNSAP VKGFEKDVGS KTTLRITYPE 190 200 210 220 230 240 GAMQRPEQYE RDSLFVLAGF KWQDFKWLKY IVYKERVSAS DGFWKSVATR VPKEPPEIRI 250 260 270 280 290 300 LNPYFIQEAA FTLIGLPFNN GLMGRGNIPT LGSVAVTMAL HGCDEVAVAG FGYDMSTPNA 310 320 330 340 PLHYYETVRM AAIKESWTHN IQREKEFLRK LVKARVITDL SSGI
	Isoform B4 [UniParc]. Checksum: 7C84EE03A5D6ABCE	FASTA	277	31,587
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 160 170 180 REFVPPFGIK GQDNLIKAIL SVTKEYRLTP ALDSLRCRRC IIVGNGGVLA NKSLGSRIDD 190 200 210 220 230 240 YDIVVRLNSA PVKGFEKDVG SKTTLRITYP EGAMQRPEQY ERDSLFVLAG FKWQDFKWLK 250 260 270 YIVYKERVSW THNIQREKEF LRKLVKARVI TDLSSGI
	Isoform B4+173 [UniParc]. Checksum: 933010B3A0B41729	FASTA	115	12,969
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP REKVRTFMAW LAWYG
	Isoform B5+26 [UniParc]. Checksum: E56B89AAF01B90F8	FASTA	186	20,837
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 160 170 180 REFVPPFGIK GQDNLIKAIL SVTKEYRLTP ALDSLRCRRC IIVGNGGVLA NKSLGSRIDD YDIVVR
	Isoform B5+173 [UniParc]. Checksum: 709ABCEF09B26251	FASTA	121	13,691
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RAKRNGAWRQ KHIQAYVLRQ R
	Isoform B7 [UniParc]. Checksum: A881E409E96468F9	FASTA	155	17,428
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 REFVPPFGIK GQVLDAQYPA RERVSAEAGE SSRHH
	Isoform B8 [UniParc]. Checksum: DF45CA4E6D931B3D	FASTA	429	48,034
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL SPRTLCTVVF GLDCILESPG EPKKLLMPAS HPLEILKSLS EDTAFALGFL 130 140 150 160 170 180 KLPRPAELAT KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP 190 200 210 220 230 240 FGIKGQDNLI KAILSVTKEY RLTPALDSLR CRRCIIVGNG GVLANKSLGS RIDDYDIVVR 250 260 270 280 290 300 LNSAPVKGFE KDVGSKTTLR ITYPEGAMQR PEQYERDSLF VLAGFKWQDF KWLKYIVYKE 310 320 330 340 350 360 RVSASDGFWK SVATRVPKEP PEIRILNPYF IQEAAFTLIG LPFNNGLMGR GNIPTLGSVA 370 380 390 400 410 420 VTMALHGCDE VAVAGFGYDM STPNAPLHYY ETVRMAAIKE SWTHNIQREK EFLRKLVKAR VITDLSSGI
	Isoform B10 [UniParc]. Checksum: 8EF2DF5A045B8511	FASTA	151	16,834
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSN SVVLSFDSAG QTLGSEYDRL 70 80 90 100 110 120 GFLLNLDSKL PAELATKYAN FSEGACKPGY ASALMTAIFP RFSKPAPMFL DDSFRKWARI 130 140 150 REFVPPFGIK GQECIGWLLE ICGHSSAQGA P
	Isoform C1 [UniParc]. Checksum: 8A84C7FB0ABDD7C9	FASTA	359	40,606
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 110 120 KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP FGIKGQDNLI 130 140 150 160 170 180 KAILSVTKEY RLTPALDSLR CRRCIIVGNG GVLANKSLGS RIDDYDIVVR LNSAPVKGFE 190 200 210 220 230 240 KDVGSKTTLR ITYPEGAMQR PEQYERDSLF VLAGFKWQDF KWLKYIVYKE RVSASDGFWK 250 260 270 280 290 300 SVATRVPKEP PEIRILNPYF IQEAAFTLIG LPFNNGLMGR GNIPTLGSVA VTMALHGCDE 310 320 330 340 350 VAVAGFGYDM STPNAPLHYY ETVRMAAIKE SWTHNIQREK EFLRKLVKAR VITDLSSGI
	Isoform C4 [UniParc]. Checksum: 3DC939A6817E18B0	FASTA	261	30,022
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 110 120 KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP FGIKGQDNLI 130 140 150 160 170 180 KAILSVTKEY RLTPALDSLR CRRCIIVGNG GVLANKSLGS RIDDYDIVVR LNSAPVKGFE 190 200 210 220 230 240 KDVGSKTTLR ITYPEGAMQR PEQYERDSLF VLAGFKWQDF KWLKYIVYKE RVSWTHNIQR 250 260 EKEFLRKLVK ARVITDLSSG I
	Isoform C5 [UniParc]. Checksum: 1E7D22F363B85B30	FASTA	186	20,984
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 110 120 KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP FGIKGQDNLI 130 140 150 160 170 180 KAILSVTKEY RLTPALDSLR CRRCIIVGNG GVLANKSLGS RIDDYDIVVS PGRTISSERK SFCGSW
	Isoform C7 [UniParc]. Checksum: 04B51A49F74C6F42	FASTA	139	15,863
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 110 120 KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP FGIKGQVLDA 130 QYPARERVSA EAGESSRHH
	Isoform C8 [UniParc]. Checksum: 1CD13FC0AEB4560D	FASTA	413	46,469
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLSPRTLC 70 80 90 100 110 120 TVVFGLDCIL ESPGEPKKLL MPASHPLEIL KSLSEDTAFA LGFLKLPRPA ELATKYANFS 130 140 150 160 170 180 EGACKPGYAS ALMTAIFPRF SKPAPMFLDD SFRKWARIRE FVPPFGIKGQ DNLIKAILSV 190 200 210 220 230 240 TKEYRLTPAL DSLRCRRCII VGNGGVLANK SLGSRIDDYD IVVRLNSAPV KGFEKDVGSK 250 260 270 280 290 300 TTLRITYPEG AMQRPEQYER DSLFVLAGFK WQDFKWLKYI VYKERVSASD GFWKSVATRV 310 320 330 340 350 360 PKEPPEIRIL NPYFIQEAAF TLIGLPFNNG LMGRGNIPTL GSVAVTMALH GCDEVAVAGF 370 380 390 400 410 GYDMSTPNAP LHYYETVRMA AIKESWTHNI QREKEFLRKL VKARVITDLS SGI
	Isoform C9 [UniParc]. Checksum: 87D5C4311A1FE514	FASTA	228	25,558
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 110 120 KYANFSEGAC KPGYASALMT AIFPRFSKPA PMFLDDSFRK WARIREFVPP FGIKGQDNLI 130 140 150 160 170 180 KAILSVTKEY RLTPALDSLR CRRCIIVGNG GVLANKSLGS RIDDYDIVVR VHRMASGNLW 190 200 210 220 PLECPRSPLR FESSTHISSR RPPSPSLACP STMASWAGGT SLPLAVWQ
	Isoform C11 [UniParc]. Checksum: 073EA4B17DC68FB0	FASTA	230	26,763
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLFSKPAP 70 80 90 100 110 120 MFLDDSFRKW ARIREFVPPF GIKGQDNLIK AILSVTKEYR LTPALDSLRC RRCIIVGNGG 130 140 150 160 170 180 VLANKSLGSR IDDYDIVVRL NSAPVKGFEK DVGSKTTLRI TYPEGAMQRP EQYERDSLFV 190 200 210 220 230 LAGFKWQDFK WLKYIVYKER VSWTHNIQRE KEFLRKLVKA RVITDLSSGI
	Isoform C12 [UniParc]. Checksum: 33196D8AF2BED686	FASTA	101	11,444
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSK YDRLGFLLNL DSKLPAELAT 70 80 90 100 KYANFSEGAC KPGYASALMT AIFPRPGRTI SSERKSFCGS W
	Isoform D2+26 [UniParc]. Checksum: C50EA375D4F01821	FASTA	185	20,887
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVAEYDRLG 70 80 90 100 110 120 FLLNLDSKLP AELATKYANF SEGACKPGYA SALMTAIFPR FSKPAPMFLD DSFRKWARIR 130 140 150 160 170 180 EFVPPFGIKG QDNLIKAILS VTKEYRLTPA LDSLRCRRCI IVGNGGVLAN KSLGSRIDDY DIVVR
	Isoform D5 [UniParc]. Checksum: 14056E7DD7DD50AB	FASTA	201	22,598
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS KYSHSSSPQE KPVAEYDRLG 70 80 90 100 110 120 FLLNLDSKLP AELATKYANF SEGACKPGYA SALMTAIFPR FSKPAPMFLD DSFRKWARIR 130 140 150 160 170 180 EFVPPFGIKG QDNLIKAILS VTKEYRLTPA LDSLRCRRCI IVGNGGVLAN KSLGSRIDDY 190 200 DIVVSPGRTI SSERKSFCGS W
	Isoform E1 [UniParc]. Checksum: 9E7CF581E6CD3813	FASTA	43	5,056
	10 20 30 40 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS LLN
	Isoform E3+32 [UniParc]. Checksum: DE5BE566E4BDF07D	FASTA	73	8,178
	10 20 30 40 50 60 MGLLVFVRNL LLALCLFLVL GFLYYSAWKL HLLQWEEDSS SPSQHPCSWM TPFASGLESG 70 SSCRLLGSKV KTI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase." Kitagawa H., Paulson J.C. Biochem. Biophys. Res. Commun. 194:375-382(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B1). Tissue: Placenta.
[2]	"Structural variations of the alpha 2,3-sialyltransferase III, ST3GalIII, transcripts in human peripheral white blood cells." Grahn A., Larson G. Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A1; A7; A8; B1; B1-90; B1+32; B3; B4; B4+173; B5+26; B5+173; B7; B8; C1; C7; C8; D2+26; E1 AND E3+32).
[3]	"Structural variations of the alpha 2,3-sialyltransferase III, ST3GalIII, transcripts in human fetal brain." Grahn A., Larson G. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS B10; C4; C5; C9; C11; C12 AND D5). Tissue: Fetal brain.
[4]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B1). Tissue: Brain.
[7]	"ST3GAL3 mutations impair the development of higher cognitive functions." Hu H., Eggers K., Chen W., Garshasbi M., Motazacker M.M., Wrogemann K., Kahrizi K., Tzschach A., Hosseini M., Bahman I., Hucho T., Muhlenhoff M., Gerardy-Schahn R., Najmabadi H., Ropers H.H., Kuss A.W. Am. J. Hum. Genet. 89:407-414(2011) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANTS MRT12 ASP-13 AND TYR-370, CHARACTERIZATION OF VARIANTS MRT12 ASP-13 AND TYR-370.
+	Additional computationally mapped references.

Web resources

GGDB

GlycoGene database

Functional Glycomics Gateway - GTase

ST3Gal III

Cross-references

Sequence databases
EMBL GenBank DDBJ	L23768 mRNA. Translation: AAA35778.1. AF425851 mRNA. Translation: AAO13859.1. AF425852 mRNA. Translation: AAO13860.1. AF425853 mRNA. Translation: AAO13861.1. AF425854 mRNA. Translation: AAO13862.1. AF425855 mRNA. Translation: AAO13863.1. AF425856 mRNA. Translation: AAO13864.1. AF425857 mRNA. Translation: AAO13865.1. AF425858 mRNA. Translation: AAO13866.1. AF425859 mRNA. Translation: AAO13867.1. AF425860 mRNA. Translation: AAO13868.1. AF425861 mRNA. Translation: AAO13869.1. AF425862 mRNA. Translation: AAO13870.1. AF425863 mRNA. Translation: AAO13871.1. AF425864 mRNA. Translation: AAO13872.1. AF425865 mRNA. Translation: AAO13873.1. AF425866 mRNA. Translation: AAO13874.1. AF425867 mRNA. Translation: AAO13875.1. AF425868 mRNA. Translation: AAO13876.1. AF425869 mRNA. Translation: AAO13877.1. AY167992 mRNA. Translation: AAO38806.1. AY167993 mRNA. Translation: AAO38807.1. AY167994 mRNA. Translation: AAO38808.1. AY167995 mRNA. Translation: AAO38809.1. AY167996 mRNA. Translation: AAO38810.1. AY167997 mRNA. Translation: AAO38811.1. AY167998 mRNA. Translation: AAO38812.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71022.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71023.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71024.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71025.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71027.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71028.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71029.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71031.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71032.1. AL451062, AL357079, AL592548 Genomic DNA. Translation: CAH71033.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16785.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16786.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16787.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16789.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16790.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16791.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16792.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16793.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16794.1. AL357079, AL451062, AL592548 Genomic DNA. Translation: CAI16795.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22181.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22182.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22183.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22184.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22186.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22188.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22189.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22190.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22191.1. AL592548, AL357079, AL451062 Genomic DNA. Translation: CAI22192.1. CH471059 Genomic DNA. Translation: EAX07082.1. CH471059 Genomic DNA. Translation: EAX07083.1. BC050380 mRNA. Translation: AAH50380.1.
IPI	IPI00009630. IPI00181505. IPI00185243. IPI00185245. IPI00185248. IPI00185251. IPI00217388. IPI00217392. IPI00217399. IPI00217400. IPI00217406. IPI00238891. IPI00293210. IPI00329676. IPI00383492. IPI00383493. IPI00383494. IPI00384239. IPI00384243. IPI00413068. IPI00413072. IPI00413074. IPI00413075. IPI00413078. IPI00413079. IPI00413081.
PIR	JN0618.
RefSeq	NP_001257388.1. NM_001270459.1. NP_001257389.1. NM_001270460.1. NP_001257390.1. NM_001270461.1. NP_001257391.1. NM_001270462.1. NP_001257392.1. NM_001270463.1. NP_001257393.1. NM_001270464.1. NP_001257394.1. NM_001270465.1. NP_001257395.1. NM_001270466.1. NP_006270.1. NM_006279.3. NP_777623.2. NM_174963.3. NP_777624.1. NM_174964.2. NP_777625.1. NM_174965.2. NP_777626.1. NM_174966.2. NP_777627.1. NM_174967.2. NP_777628.2. NM_174968.3. NP_777629.1. NM_174969.2. NP_777630.1. NM_174970.2. NP_777631.2. NM_174971.3.
UniGene	Hs.597915.
3D structure databases
ProteinModelPortal	Q11203.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q11203. 5 interactions.
MINT	MINT-1397196.
Protein family/group databases
CAZy	GT29. Glycosyltransferase Family 29.
PTM databases
PhosphoSite	Q11203.
Polymorphism databases
DMDM	1705561.
Proteomic databases
PaxDb	Q11203.
PRIDE	Q11203.
Protocols and materials databases
DNASU	6487.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000262915; ENSP00000262915; ENSG00000126091. ENST00000330208; ENSP00000333494; ENSG00000126091. ENST00000332628; ENSP00000329755; ENSG00000126091. ENST00000335430; ENSP00000335633; ENSG00000126091. ENST00000347631; ENSP00000317192; ENSG00000126091. ENST00000351035; ENSP00000316999; ENSG00000126091. ENST00000353126; ENSP00000330463; ENSG00000126091. ENST00000361392; ENSP00000355341; ENSG00000126091. ENST00000361400; ENSP00000354748; ENSG00000126091. ENST00000361746; ENSP00000354657; ENSG00000126091. ENST00000361812; ENSP00000355201; ENSG00000126091. ENST00000372362; ENSP00000361437; ENSG00000126091. ENST00000372365; ENSP00000361440; ENSG00000126091. ENST00000372366; ENSP00000361441; ENSG00000126091. ENST00000372367; ENSP00000361442; ENSG00000126091. ENST00000372368; ENSP00000361443; ENSG00000126091. ENST00000372369; ENSP00000361444; ENSG00000126091. ENST00000372372; ENSP00000361447; ENSG00000126091. ENST00000372374; ENSP00000361449; ENSG00000126091. ENST00000372375; ENSP00000361450; ENSG00000126091. ENST00000372377; ENSP00000361452; ENSG00000126091. ENST00000469715; ENSP00000431700; ENSG00000126091. ENST00000489897; ENSP00000437206; ENSG00000126091. ENST00000490541; ENSP00000435018; ENSG00000126091. ENST00000528371; ENSP00000434876; ENSG00000126091. ENST00000530581; ENSP00000437293; ENSG00000126091. ENST00000531451; ENSP00000435603; ENSG00000126091. ENST00000531816; ENSP00000434378; ENSG00000126091. ENST00000531993; ENSP00000432682; ENSG00000126091. ENST00000533212; ENSP00000435621; ENSG00000126091. ENST00000533933; ENSP00000432965; ENSG00000126091. ENST00000533997; ENSP00000432071; ENSG00000126091. ENST00000545417; ENSP00000439634; ENSG00000126091.
GeneID	6487.
KEGG	hsa:6487.
UCSC	uc001cka.3. human. uc001ckb.3. human. uc001ckc.3. human. uc001ckd.3. human. uc001cke.3. human. uc001ckf.3. human. uc001ckg.3. human. uc001cki.3. human. uc001ckk.3. human. uc001ckl.3. human. uc001ckm.3. human. uc001cko.3. human. uc001ckp.3. human. uc001ckq.3. human. uc001ckr.3. human. uc009vwv.3. human. uc009vxb.3. human.
Organism-specific databases
CTD	6487.
GeneCards	GC01P044173.
HGNC	HGNC:10866. ST3GAL3.
HPA	HPA051102.
MIM	606494. gene. 611090. phenotype.
neXtProt	NX_Q11203.
Orphanet	88616. Autosomal recessive nonsyndromic intellectual deficit.
PharmGKB	PA35768.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG257001.
HOVERGEN	HBG056676.
KO	K00781.
OMA	IQEAAFS.
OrthoDB	EOG4B8JD6.
Enzyme and pathway databases
Reactome	REACT_111102. Signal Transduction. REACT_111217. Metabolism. REACT_116125. Disease. REACT_17015. Metabolism of proteins.
UniPathway	UPA00378.
Gene expression databases
ArrayExpress	Q11203.
Bgee	Q11203.
Genevestigator	Q11203.
GermOnline	ENSG00000126091. Homo sapiens.
Family and domain databases
InterPro	IPR001675. Glyco_trans_29. IPR012163. Sialyl_trans. [Graphical view]
Pfam	PF00777. Glyco_transf_29. 1 hit. [Graphical view]
PIRSF	PIRSF005557. Sialyl_trans. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	ST3GAL3. human.
GenomeRNAi	6487.
NextBio	25195.
SOURCE	Search...

Entry information

Entry name

SIAT6_HUMAN

Accession

Primary (citable) accession number: Q11203
Secondary accession number(s): A9Z1W2 , D3DPX8, Q5T4W9, Q5T4X0, Q5T4X7, Q5T4X8, Q5T4X9, Q5T4Y0, Q5T4Y2, Q5T4Y3, Q5T4Y4, Q86UR6, Q86UR7, Q86UR8, Q86UR9, Q86US0, Q86US1, Q86US2, Q8IX41, Q8IX42, Q8IX43, Q8IX44, Q8IX45, Q8IX46, Q8IX47, Q8IX48, Q8IX49, Q8IX50, Q8IX51, Q8IX52, Q8IX53, Q8IX54, Q8IX55, Q8IX56, Q8IX57, Q8IX58

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 122 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.