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Protein

Histidine kinase

Gene

Tery_2729

Organism
Trichodesmium erythraeum (strain IMS101)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Two-component regulatory systemSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTERY203124:GJDR-2754-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Tery_2729Imported
OrganismiTrichodesmium erythraeum (strain IMS101)Imported
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium
ProteomesiUP000008878 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi203124.Tery_2729.

Structurei

3D structure databases

ProteinModelPortaliQ111B1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000120898.
OMAiQINANTH.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR004010. Cache_domain.
IPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003660. HAMP_linker_domain.
IPR003594. HATPase_C.
IPR029787. Nucleotide_cyclase.
IPR029151. Sensor-like.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02743. Cache_1. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF103190. SSF103190. 1 hit.
SSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q111B1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKYLSRLF AQISGKVPLR TTLILPFIVQ VFGVVGLIGY ISIENSQRAI
60 70 80 90 100
NDVVNQLLNE QVARVEQNLE AYLRVPHQVN QINATTIRNG QLDLENTSQL
110 120 130 140 150
ENYFWQQLQI FDVLGFTGLG LENKVNLGAE RLTQDTLHLR ISTQESNYIF
160 170 180 190 200
ETYSTNQFGE RVQLLNSIKF DPRTRPWYKA AVASGQPTWS EIYPNTAGLT
210 220 230 240 250
AYLGASKAFY NDQGKLQGVL LTNINLSQIG DFLGSLEIGK TGQIFILERS
260 270 280 290 300
GMLVATSTGE KPFRTINKAY GAERVQAIES YNDLTQATAK YLSTEFDLNK
310 320 330 340 350
LINDGKYLQF KINNQRQFLN IKPFQDQYGL DWLIVIVIPE IDFLDNIYKQ
360 370 380 390 400
TKITIILCLL ALVLATVIGI LTSRWVVQPI LKLKDVATAL SEGEFNQKIE
410 420 430 440 450
LNRDDEVGEL AKAFNSMAFQ LQNSFNLLTI KNKQLENLDK LKDEFLANTS
460 470 480 490 500
HELRTPLNGI IGITESLIDG VAGELSSEVK NNLYLVIFSG KRLSNLINDI
510 520 530 540 550
LDFYKLKHRN IELKLKPVGV REVAEIVINL SSSMIGTKPL QIINSISYDI
560 570 580 590 600
PFVDADENRL QQIFYNLVGN AVKFTDSGKI EVSAKVLENQ LENSSNNVSL
610 620 630 640 650
LEITVSDTGI GIPSDKLDQI FESFEQANGS TSREYGGTGL GLAITKKLVE
660 670 680 690 700
LHKGSLCVLS EVGVGSQFKF TIPISKTQVV NFPQVTLSPS IPLVTDFEPK
710 720 730 740 750
SKDVKLQYLE AEMGDFTVLI VDDEPVNLQV IRNNLALQNY AITEANNGIE
760 770 780 790 800
ALEMIEKGLM PDLILLDVMM PHMTGYEVAK KLREKYLHIE LPIIMLTAKP
810 820 830 840 850
LVSDLVEGFV SGANDYLIKP FSKQELLARI KIHIRLSKIS SAYNRFVPHN
860 870 880 890 900
FVQLLNSESI VDVKLGDSIK QKMSILFSDI RSFTTLSESM TPEENFKFIN
910 920 930 940 950
AYLSRMEPAI LDNEGFIDKY IGDAIMAIFI RKADDAVQAA INMLKNLADF
960 970 980 990 1000
NQERQKLSQE MIKIGIGINT GDLMLGIVGG ERRIDGTVIS DAVNLGSRLE
1010 1020 1030 1040 1050
SLTKLYGVNI LISENTLLNL EEAYKYNYRF LDKVKVKGKK QAVGLFEIFD
1060 1070 1080 1090 1100
GDPEEQKELK KQTKTKFEQA VFLYFQQKFA TAKQIMIEIL QINPEDKVAQ
1110
FYIRRFDESK LIEELKDGE
Length:1,119
Mass (Da):125,944
Last modified:August 22, 2006 - v1
Checksum:i572E02D37C1EB391
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG51913.1.
RefSeqiYP_722386.1. NC_008312.1.

Genome annotation databases

EnsemblBacteriaiABG51913; ABG51913; Tery_2729.
GeneIDi4244994.
KEGGiter:Tery_2729.
PATRICi23990096. VBITriEry99848_3473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG51913.1.
RefSeqiYP_722386.1. NC_008312.1.

3D structure databases

ProteinModelPortaliQ111B1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203124.Tery_2729.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG51913; ABG51913; Tery_2729.
GeneIDi4244994.
KEGGiter:Tery_2729.
PATRICi23990096. VBITriEry99848_3473.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000120898.
OMAiQINANTH.
OrthoDBiEOG6G4VQG.

Enzyme and pathway databases

BioCyciTERY203124:GJDR-2754-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR004010. Cache_domain.
IPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003660. HAMP_linker_domain.
IPR003594. HATPase_C.
IPR029787. Nucleotide_cyclase.
IPR029151. Sensor-like.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02743. Cache_1. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF103190. SSF103190. 1 hit.
SSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMS101Imported.

Entry informationi

Entry nameiQ111B1_TRIEI
AccessioniPrimary (citable) accession number: Q111B1
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: April 1, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.