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Protein

Uncharacterized protein C05D10.4

Gene

C05D10.4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C05D10.4
Gene namesi
ORF Names:C05D10.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome III

Organism-specific databases

WormBaseiC05D10.4a; CE30423; WBGene00015480.
C05D10.4b; CE30424; WBGene00015480.
C05D10.4c; CE30425; WBGene00015480.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 597597Uncharacterized protein C05D10.4PRO_0000065146Add
BLAST

Proteomic databases

PRIDEiQ11181.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
abl-1P039496EBI-2316016,EBI-2315883

Protein-protein interaction databases

BioGridi41081. 1 interaction.
IntActiQ11181. 8 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ11181.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini402 – 46564SAMPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi280 – 31233Ser-richAdd
BLAST

Sequence similaritiesi

Contains 1 SAM (sterile alpha motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG321295.
HOGENOMiHOG000022028.
InParanoidiQ11181.
OMAiFKSALML.
OrthoDBiEOG7X6M04.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
[Graphical view]
PfamiPF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform b (identifier: Q11181-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTARPYEPPP DYFCTHLLKN HQIEWKKPVK AKASPIHLFV FLREPMIEQR
60 70 80 90 100
WPTTVRNSSI HPHVSSAHPS YRSHSIDAAV NRSSSACFHS PHRPSFPSRG
110 120 130 140 150
LQKYDYPICG VSPSRHLSYN HFYNQSAAEI EEMLRTRQFP EIAGIYGNDE
160 170 180 190 200
QPSLRRFTRY NQSINSRAVP PPAPPNPPKM EKHMSHDTSG RGSIFSKSSK
210 220 230 240 250
KPLFFMGNWT FRDRNKSARP SISEALREER PQSMNLSDIK PATRSKSGEV
260 270 280 290 300
LGPRNHIHIE SITEFPRNIE TRVPVKIERS SMVRRKPSNM GGSTEVSITS
310 320 330 340 350
SSPSPSSSSS TSTGEFKTTI TVDDDHQPTA VMRPKKESDT RGTLNNNRYS
360 370 380 390 400
FQSCVQLRKS CPDLDSTAMS NMEQHRVSKK RTRRAKEKMS QAAWKRKTVK
410 420 430 440 450
EWSLDDVLLW LQSAQMDDVA GLLIGYDLRG EDLLQWNDQT LAQLGVSNPE
460 470 480 490 500
IRKKLLDDLS KIIENGPEPA QEDIRNNHRT LFDIVKQTSY DQVLAVETPL
510 520 530 540 550
TTRDITVTHG RLGCLQITKV NGANLPLKEH DCLLEINERA GEQFKSALML
560 570 580 590
TKLISDSNGA AIRFVVLRRK TNLVVEESQQ KESSSSGISS SPQTPTE

Note: No experimental confirmation available.

Length:597
Mass (Da):67,535
Last modified:July 19, 2003 - v2
Checksum:i5860EFD1FCB21244
GO
Isoform a (identifier: Q11181-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     13-44: Missing.

Note: No experimental confirmation available.

Show »
Length:565
Mass (Da):63,694
Checksum:iBFA443E23FCD92C2
GO
Isoform c (identifier: Q11181-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-179: Missing.

Note: No experimental confirmation available.

Show »
Length:418
Mass (Da):46,941
Checksum:i1D1969FCACE898BF
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 179179Missing in isoform c. CuratedVSP_007785Add
BLAST
Alternative sequencei13 – 4432Missing in isoform a. CuratedVSP_007786Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080362 Genomic DNA. Translation: CCD63177.1.
FO080362 Genomic DNA. Translation: CCD63178.1.
FO080362 Genomic DNA. Translation: CCD63179.1.
PIRiC88474.
RefSeqiNP_498323.2. NM_065922.4. [Q11181-2]
NP_498324.2. NM_065923.4. [Q11181-1]
NP_741170.1. NM_171149.3. [Q11181-3]
UniGeneiCel.5024.

Genome annotation databases

EnsemblMetazoaiC05D10.4b; C05D10.4b; WBGene00015480. [Q11181-1]
GeneIDi175860.
KEGGicel:CELE_C05D10.4.
UCSCiC05D10.4b. c. elegans. [Q11181-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080362 Genomic DNA. Translation: CCD63177.1.
FO080362 Genomic DNA. Translation: CCD63178.1.
FO080362 Genomic DNA. Translation: CCD63179.1.
PIRiC88474.
RefSeqiNP_498323.2. NM_065922.4. [Q11181-2]
NP_498324.2. NM_065923.4. [Q11181-1]
NP_741170.1. NM_171149.3. [Q11181-3]
UniGeneiCel.5024.

3D structure databases

ProteinModelPortaliQ11181.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi41081. 1 interaction.
IntActiQ11181. 8 interactions.

Proteomic databases

PRIDEiQ11181.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC05D10.4b; C05D10.4b; WBGene00015480. [Q11181-1]
GeneIDi175860.
KEGGicel:CELE_C05D10.4.
UCSCiC05D10.4b. c. elegans. [Q11181-1]

Organism-specific databases

CTDi175860.
WormBaseiC05D10.4a; CE30423; WBGene00015480.
C05D10.4b; CE30424; WBGene00015480.
C05D10.4c; CE30425; WBGene00015480.

Phylogenomic databases

eggNOGiNOG321295.
HOGENOMiHOG000022028.
InParanoidiQ11181.
OMAiFKSALML.
OrthoDBiEOG7X6M04.

Miscellaneous databases

NextBioi890016.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
[Graphical view]
PfamiPF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
    Strain: Bristol N2.

Entry informationi

Entry nameiYPC4_CAEEL
AccessioniPrimary (citable) accession number: Q11181
Secondary accession number(s): Q8T3F3, Q8T3F4, Q8T3F5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 19, 2003
Last modified: January 7, 2015
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.