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Q11121 (PLB1_TORDE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysophospholipase

EC=3.1.1.5
Alternative name(s):
Phospholipase B
OrganismTorulaspora delbrueckii (Yeast) (Candida colliculosa)
Taxonomic identifier4950 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeTorulaspora

Protein attributes

Sequence length649 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the release of fatty acids from lysophospholipids.

Catalytic activity

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

Subcellular location

Secreted.

Sequence similarities

Belongs to the lysophospholipase family.

Contains 1 PLA2c domain.

Ontologies

Keywords
   Biological processLipid degradation
Lipid metabolism
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processphospholipid catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionlysophospholipase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121
Chain22 – 649628Lysophospholipase
PRO_0000024645

Regions

Domain34 – 584551PLA2c
Compositional bias612 – 6176Poly-Ser

Amino acid modifications

Glycosylation321N-linked (GlcNAc...) Potential
Glycosylation511N-linked (GlcNAc...) Potential
Glycosylation771N-linked (GlcNAc...) Potential
Glycosylation901N-linked (GlcNAc...) Potential
Glycosylation1211N-linked (GlcNAc...) Potential
Glycosylation1581N-linked (GlcNAc...) Potential
Glycosylation1681N-linked (GlcNAc...) Potential
Glycosylation2131N-linked (GlcNAc...) Potential
Glycosylation2751N-linked (GlcNAc...) Potential
Glycosylation3431N-linked (GlcNAc...) Potential
Glycosylation3861N-linked (GlcNAc...) Potential
Glycosylation4571N-linked (GlcNAc...) Potential
Glycosylation4871N-linked (GlcNAc...) Potential
Glycosylation5111N-linked (GlcNAc...) Potential
Glycosylation5391N-linked (GlcNAc...) Potential
Glycosylation5631N-linked (GlcNAc...) Potential
Glycosylation5801N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q11121 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: CC6901D168D01459

FASTA64971,111
        10         20         30         40         50         60 
MNLKEWLLFS DAVFFAQGTL AWSPSNSYTP ANVSCDEDIN LIRQASGPSD NETEWLKKRD 

        70         80         90        100        110        120 
VYTREALRSF LDRATSNFSD SSLVSQLFSN ASDIPRIAVA CSGGGYRAML SGAGMLAAMD 

       130        140        150        160        170        180 
NRTDGANEHG LGGLLQSTTY LAGLSGGNWL VGTLAWNNWT SVQDIVNNMT EDDSIWDISN 

       190        200        210        220        230        240 
SIINPGGFMI VTTIKRWDHI SDAVEGKQDA GFNVSLTDIW GRALSYNFFP SLYRGGVAYT 

       250        260        270        280        290        300 
WSTLRDVEVF QNGEMPFPIS VADGRYPGTQ IIDLNATVFE FNPFEMGSWD PTLNAFTDVK 

       310        320        330        340        350        360 
YLGTKVSNGE PVNKGQCVAG YDNTGFIMGT SSSLFNQFLL QINSTSLPSF IKNLVTGFLD 

       370        380        390        400        410        420 
DLSEDEDDIA IYAPNPFKDT SYIQDNFSKS ISESDYLYLV DGGEDNQNIP LVPLVQDERN 

       430        440        450        460        470        480 
VDVIFALDNS ADTDYYWPDG ASLVSTYERQ FSSQGLNMSF PYVPDKRTFV NLGLADKPSF 

       490        500        510        520        530        540 
FGCDAQNLTD LNYIPPLVVY IPNARHSYNS NTSTFKLSYT DDERLKMIKN GFEAATRGNL 

       550        560        570        580        590        600 
TDDSSFMGCV ACAVMRRKQQ SLNATLPEEC STCFTNYCWN GTIDDTPVSG LDNSDFDPTA 

       610        620        630        640 
ASSAYSAYNT ESYSSSSATG SKKNGAGLPA TPTSFTSILT LLTAIAGFL 

« Hide

References

[1]"Cloning and sequencing of phospholipase B gene from the yeast Torulaspora delbrueckii."
Watanabe Y., Yashiki Y., Sultana G.N., Maruyama M., Kangawa K., Tamai Y.
FEMS Microbiol. Lett. 124:29-34(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
Strain: YL-32.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D32134 Genomic DNA. Translation: BAA06860.1.

3D structure databases

ProteinModelPortalQ11121.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMSSF52151. SSF52151. 1 hit.
PROSITEPS51210. PLA2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePLB1_TORDE
AccessionPrimary (citable) accession number: Q11121
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families