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Protein

Putative tyrosine-protein kinase C03B1.5

Gene

C03B1.5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei62ATPPROSITE-ProRule annotation1
Active sitei155Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 39ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase, Tyrosine-protein kinase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ11112.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein kinase C03B1.5 (EC:2.7.10.2)
Gene namesi
ORF Names:C03B1.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiC03B1.5; CE37605; WBGene00015376.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000881871 – 328Putative tyrosine-protein kinase C03B1.5Add BLAST328

Proteomic databases

PaxDbiQ11112.

Expressioni

Gene expression databases

BgeeiWBGene00015376.

Interactioni

Protein-protein interaction databases

STRINGi6239.C03B1.5.

Structurei

3D structure databases

ProteinModelPortaliQ11112.
SMRiQ11112.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 288Protein kinasePROSITE-ProRule annotationAdd BLAST264

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0201. Eukaryota.
ENOG410XP9G. LUCA.
GeneTreeiENSGT00530000062954.
HOGENOMiHOG000076925.
InParanoidiQ11112.
OMAiMCLEYAA.
OrthoDBiEOG091G0IZ2.
PhylomeDBiQ11112.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11112-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSAQKSKTN GDTSLFLMKD IPQYWSPALK IGSGAFGEVM LVHSDRLDAR
60 70 80 90 100
GEQILHNEFA LKVIRFPECD YHKIIREVNT HTLCRHHDNV LFIGSIYCQT
110 120 130 140 150
FQQGLRVQMC LEYAALSDLS LLASSETFES HVAYICKNLI SALIHIHNLG
160 170 180 190 200
IVHGDLSVKN ILMTHEGVVK LSDFGMANTF EQTRKSKNQS ILGTPGFIAP
210 220 230 240 250
EIINLQGYDG KADLWGLGIL SLFLLKGENP FKKCTQFDLE SYKVSISESF
260 270 280 290 300
YPDYSNYSTP LQEFMSSLKD YNPEFRSSAL HASSQTYLKT SCSQSEILNY
310 320
YKRLRRTRGM DLPWPEEIHT FSVPVSLE
Length:328
Mass (Da):37,213
Last modified:May 10, 2005 - v3
Checksum:iB709F2DA658F309F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080304 Genomic DNA. Translation: CCD62741.1.
PIRiT15383.
RefSeqiNP_509065.2. NM_076664.4.
UniGeneiCel.11493.

Genome annotation databases

EnsemblMetazoaiC03B1.5; C03B1.5; WBGene00015376.
GeneIDi182148.
KEGGicel:CELE_C03B1.5.
UCSCiC03B1.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080304 Genomic DNA. Translation: CCD62741.1.
PIRiT15383.
RefSeqiNP_509065.2. NM_076664.4.
UniGeneiCel.11493.

3D structure databases

ProteinModelPortaliQ11112.
SMRiQ11112.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C03B1.5.

Proteomic databases

PaxDbiQ11112.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC03B1.5; C03B1.5; WBGene00015376.
GeneIDi182148.
KEGGicel:CELE_C03B1.5.
UCSCiC03B1.5. c. elegans.

Organism-specific databases

CTDi182148.
WormBaseiC03B1.5; CE37605; WBGene00015376.

Phylogenomic databases

eggNOGiKOG0201. Eukaryota.
ENOG410XP9G. LUCA.
GeneTreeiENSGT00530000062954.
HOGENOMiHOG000076925.
InParanoidiQ11112.
OMAiMCLEYAA.
OrthoDBiEOG091G0IZ2.
PhylomeDBiQ11112.

Enzyme and pathway databases

SignaLinkiQ11112.

Miscellaneous databases

PROiQ11112.

Gene expression databases

BgeeiWBGene00015376.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYX05_CAEEL
AccessioniPrimary (citable) accession number: Q11112
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 121 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.