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Protein

Putative tyrosine-protein kinase C03B1.5

Gene

C03B1.5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei62 – 621ATPPROSITE-ProRule annotation
Active sitei155 – 1551Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi31 – 399ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase, Tyrosine-protein kinase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ11112.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein kinase C03B1.5 (EC:2.7.10.2)
Gene namesi
ORF Names:C03B1.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiC03B1.5; CE37605; WBGene00015376.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328Putative tyrosine-protein kinase C03B1.5PRO_0000088187Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi6239.C03B1.5.

Structurei

3D structure databases

ProteinModelPortaliQ11112.
SMRiQ11112. Positions 30-314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 288264Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
GeneTreeiENSGT00790000122964.
HOGENOMiHOG000076925.
InParanoidiQ11112.
OMAiMCLEYAA.
OrthoDBiEOG7GN2S0.
PhylomeDBiQ11112.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11112-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSAQKSKTN GDTSLFLMKD IPQYWSPALK IGSGAFGEVM LVHSDRLDAR
60 70 80 90 100
GEQILHNEFA LKVIRFPECD YHKIIREVNT HTLCRHHDNV LFIGSIYCQT
110 120 130 140 150
FQQGLRVQMC LEYAALSDLS LLASSETFES HVAYICKNLI SALIHIHNLG
160 170 180 190 200
IVHGDLSVKN ILMTHEGVVK LSDFGMANTF EQTRKSKNQS ILGTPGFIAP
210 220 230 240 250
EIINLQGYDG KADLWGLGIL SLFLLKGENP FKKCTQFDLE SYKVSISESF
260 270 280 290 300
YPDYSNYSTP LQEFMSSLKD YNPEFRSSAL HASSQTYLKT SCSQSEILNY
310 320
YKRLRRTRGM DLPWPEEIHT FSVPVSLE
Length:328
Mass (Da):37,213
Last modified:May 10, 2005 - v3
Checksum:iB709F2DA658F309F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080304 Genomic DNA. Translation: CCD62741.1.
PIRiT15383.
RefSeqiNP_509065.2. NM_076664.4.
UniGeneiCel.11493.

Genome annotation databases

EnsemblMetazoaiC03B1.5; C03B1.5; WBGene00015376.
GeneIDi182148.
KEGGicel:CELE_C03B1.5.
UCSCiC03B1.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080304 Genomic DNA. Translation: CCD62741.1.
PIRiT15383.
RefSeqiNP_509065.2. NM_076664.4.
UniGeneiCel.11493.

3D structure databases

ProteinModelPortaliQ11112.
SMRiQ11112. Positions 30-314.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C03B1.5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC03B1.5; C03B1.5; WBGene00015376.
GeneIDi182148.
KEGGicel:CELE_C03B1.5.
UCSCiC03B1.5. c. elegans.

Organism-specific databases

CTDi182148.
WormBaseiC03B1.5; CE37605; WBGene00015376.

Phylogenomic databases

eggNOGiCOG0515.
GeneTreeiENSGT00790000122964.
HOGENOMiHOG000076925.
InParanoidiQ11112.
OMAiMCLEYAA.
OrthoDBiEOG7GN2S0.
PhylomeDBiQ11112.

Enzyme and pathway databases

SignaLinkiQ11112.

Miscellaneous databases

NextBioi916560.
PROiQ11112.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiYX05_CAEEL
AccessioniPrimary (citable) accession number: Q11112
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 10, 2005
Last modified: May 27, 2015
This is version 107 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.