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Q11112

- YX05_CAEEL

UniProt

Q11112 - YX05_CAEEL

Protein

Putative tyrosine-protein kinase C03B1.5

Gene

C03B1.5

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 3 (10 May 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei62 – 621ATPPROSITE-ProRule annotation
    Active sitei155 – 1551Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi31 – 399ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. non-membrane spanning protein tyrosine kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Transferase, Tyrosine-protein kinase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    SignaLinkiQ11112.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein kinase C03B1.5 (EC:2.7.10.2)
    Gene namesi
    ORF Names:C03B1.5
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome X

    Organism-specific databases

    WormBaseiC03B1.5; CE37605; WBGene00015376.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 328328Putative tyrosine-protein kinase C03B1.5PRO_0000088187Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.C03B1.5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ11112.
    SMRiQ11112. Positions 20-308.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini25 – 288264Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    GeneTreeiENSGT00670000097939.
    HOGENOMiHOG000076925.
    InParanoidiQ11112.
    OMAiMCLEYAA.
    OrthoDBiEOG7GN2S0.
    PhylomeDBiQ11112.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q11112-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQSAQKSKTN GDTSLFLMKD IPQYWSPALK IGSGAFGEVM LVHSDRLDAR    50
    GEQILHNEFA LKVIRFPECD YHKIIREVNT HTLCRHHDNV LFIGSIYCQT 100
    FQQGLRVQMC LEYAALSDLS LLASSETFES HVAYICKNLI SALIHIHNLG 150
    IVHGDLSVKN ILMTHEGVVK LSDFGMANTF EQTRKSKNQS ILGTPGFIAP 200
    EIINLQGYDG KADLWGLGIL SLFLLKGENP FKKCTQFDLE SYKVSISESF 250
    YPDYSNYSTP LQEFMSSLKD YNPEFRSSAL HASSQTYLKT SCSQSEILNY 300
    YKRLRRTRGM DLPWPEEIHT FSVPVSLE 328
    Length:328
    Mass (Da):37,213
    Last modified:May 10, 2005 - v3
    Checksum:iB709F2DA658F309F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080304 Genomic DNA. Translation: CCD62741.1.
    PIRiT15383.
    RefSeqiNP_509065.2. NM_076664.4.
    UniGeneiCel.11493.

    Genome annotation databases

    EnsemblMetazoaiC03B1.5; C03B1.5; WBGene00015376.
    GeneIDi182148.
    KEGGicel:CELE_C03B1.5.
    UCSCiC03B1.5. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080304 Genomic DNA. Translation: CCD62741.1 .
    PIRi T15383.
    RefSeqi NP_509065.2. NM_076664.4.
    UniGenei Cel.11493.

    3D structure databases

    ProteinModelPortali Q11112.
    SMRi Q11112. Positions 20-308.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.C03B1.5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C03B1.5 ; C03B1.5 ; WBGene00015376 .
    GeneIDi 182148.
    KEGGi cel:CELE_C03B1.5.
    UCSCi C03B1.5. c. elegans.

    Organism-specific databases

    CTDi 182148.
    WormBasei C03B1.5 ; CE37605 ; WBGene00015376 .

    Phylogenomic databases

    eggNOGi COG0515.
    GeneTreei ENSGT00670000097939.
    HOGENOMi HOG000076925.
    InParanoidi Q11112.
    OMAi MCLEYAA.
    OrthoDBi EOG7GN2S0.
    PhylomeDBi Q11112.

    Enzyme and pathway databases

    SignaLinki Q11112.

    Miscellaneous databases

    NextBioi 916560.
    PROi Q11112.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiYX05_CAEEL
    AccessioniPrimary (citable) accession number: Q11112
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 102 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3