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Protein
Submitted name:

Probable transcriptional regulatory protein

Gene

Rv1358

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotation

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5538-MONOMER.
BRENDAi4.6.1.1. 3445.

Names & Taxonomyi

Protein namesi
Submitted name:
Probable transcriptional regulatory proteinImported
Submitted name:
Transcriptional regulatorImported
Gene namesi
Ordered Locus Names:Rv1358Imported
ORF Names:LH57_07435Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: GOC
  • plasma membrane Source: MTBBASE
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ11028.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1358.

Structurei

3D structure databases

ProteinModelPortaliQ11028.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1093 – 1158HTH luxR-type DNA-bindingInterPro annotationAdd BLAST66

Phylogenomic databases

eggNOGiENOG4105CQF. Bacteria.
COG2771. LUCA.
COG3903. LUCA.
HOGENOMiHOG000053696.
OMAiRDAHAAY.
PhylomeDBiQ11028.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.30.70.1230. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55073. SSF55073. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11028-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLSAPAFRV EPTRSRHSAL RWARHRRFAD GPRWQMLRSL QIADQIARTG
60 70 80 90 100
HMPVRRLDLI WISARNAARR ELDLGVAALV EAVTLLTADV EGSTRLSQTR
110 120 130 140 150
LNELAADYPT LDQNISEAVA AHGGVTRPVD QEVGSGLVVA FLRAGDAIAC
160 170 180 190 200
ALELQLSTLA PMRPRVGVHT GDVRLRGDGT ITGSAINESA CLRDLAHEGQ
210 220 230 240 250
TLLSAATGDL VIDQLPANTW LTDVGKYPLR GLHRQERVIQ LCHRDLRNEF
260 270 280 290 300
PPLRMSVGNR SSLPAQFTTF VGRDAQINEV QEVLTNYRLV TLRGEGGVGK
310 320 330 340 350
TRLAIQIAAA SEFRDGLCFV DLAPIADPGM VSTTAAHALG LIDRPGSSTF
360 370 380 390 400
DTLSHAIGNC HMLMVLDNCE HVLDACAELV VELLGACPEL SILATSRESI
410 420 430 440 450
GVTGEVTWVV PSLSPANEAI QLFTERARLV QPNFEIVADN FDAVSEICRR
460 470 480 490 500
LDGMPLAIEL AAARLRSLSP NEIANSLDDR FRLLTGGARS TVQRQQTLRA
510 520 530 540 550
SMDWSYALLT DTERILFRRL AVFVGGFDLT AASEVAAAGG DDFVERYSVL
560 570 580 590 600
DQLTLLVDKS LVVAEESRGS TRYRLLETVR QYALEKLNES EEIDGVRARH
610 620 630 640 650
RTHYATMAAG LNVPASTDYE QRLLQAEAEI DNLRAAFTWS RGNGDIAAAL
660 670 680 690 700
QLASALQPLW SQGRMREGLA WLESILEREG DNHLVPAGVW ARALAEKVIL
710 720 730 740 750
KAWPATSPMG APDIVAQAHH ALALARDAGD CAVLARALVA CGCGSGCDTE
760 770 780 790 800
AAQPYFAEAI ELARAINDEW TLSQIDYWQV VGIFISGQPI PLRAAAEQAR
810 820 830 840 850
ELADSIGNRF VSRQCRLFAC LAQIWEGDAN GALALSRDVT AEAEVANDVV
860 870 880 890 900
TKVLGLYVEA MALSYIGDSA ARTIAGAALE AATELGGIYQ DLGYGAITRA
910 920 930 940 950
ALAAGDVAAI EASEASWDLR NQHNVVTAHH ELMAQAALVR GDVTTARRFA
960 970 980 990 1000
DEAVLASTGW HLMMALIARA RVAIAQDELG KARDDAHAAV ACGVGVQTYL
1010 1020 1030 1040 1050
AMPDALELLA GLAGEAGNHG QAVRLFGAAA AQRQRTGEVR HKIWDAGYEA
1060 1070 1080 1090 1100
ATAALRDAMG DEDFTAAWAE GAAAPLDEAI AYAQRGRGER KRPSNGWDAL
1110 1120 1130 1140 1150
TPAEHKIVKL VTEGLVTKDI AARLFVSPRT VQTHLTHIYT KLDVTSRVQL

VQEAAQHST
Length:1,159
Mass (Da):125,056
Last modified:November 1, 1996 - v1
Checksum:i45BFD3EFE1CAAE10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14105.1.
AL123456 Genomic DNA. Translation: CCP44116.1.
RefSeqiNP_215874.1. NC_000962.3.
WP_003901139.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14105; AIR14105; LH57_07435.
CCP44116; CCP44116; Rv1358.
GeneIDi886817.
KEGGimtu:Rv1358.
mtv:RVBD_1358.
PATRICi18151578. VBIMycTub87468_1521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14105.1.
AL123456 Genomic DNA. Translation: CCP44116.1.
RefSeqiNP_215874.1. NC_000962.3.
WP_003901139.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliQ11028.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1358.

Proteomic databases

PRIDEiQ11028.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14105; AIR14105; LH57_07435.
CCP44116; CCP44116; Rv1358.
GeneIDi886817.
KEGGimtu:Rv1358.
mtv:RVBD_1358.
PATRICi18151578. VBIMycTub87468_1521.

Phylogenomic databases

eggNOGiENOG4105CQF. Bacteria.
COG2771. LUCA.
COG3903. LUCA.
HOGENOMiHOG000053696.
OMAiRDAHAAY.
PhylomeDBiQ11028.

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-5538-MONOMER.
BRENDAi4.6.1.1. 3445.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.30.70.1230. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
IPR027417. P-loop_NTPase.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55073. SSF55073. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ11028_MYCTU
AccessioniPrimary (citable) accession number: Q11028
Secondary accession number(s): I6X118, L0T6E7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 139 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.