Q10VR3 (ASPA_TRIEI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable aspartoacylase
EC=3.5.1.15

Gene names

Ordered Locus Names:

Tery_4698

Organism

Trichodesmium erythraeum (strain IMS101) [Complete proteome] [HAMAP]

Taxonomic identifier

203124 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Oscillatoriales › Trichodesmium › Trichodesmium erythraeum

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-acyl-L-aspartate + H2O = a carboxylate + L-aspartate. HAMAP-Rule MF_00704
Cofactor	Binds 1 zinc ion per subunit By similarity.
Sequence similarities	Belongs to the AspA/AstE family. Aspartoacylase subfamily.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	aspartoacylase activity Inferred from electronic annotation. Source: HAMAP hydrolase activity, acting on ester bonds Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Probable aspartoacylase HAMAP-Rule MF_00704		PRO_1000147944
Regions
	Region	63 – 64	2	Substrate binding By similarity
Sites
	Metal binding	14	1	Zinc By similarity
	Metal binding	17	1	Zinc By similarity
	Metal binding	106	1	Zinc By similarity
	Binding site	56	1	Substrate By similarity
	Binding site	165	1	Substrate By similarity
	Binding site	276	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q10VR3 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 114A67532CCB6C3E	FASTA	293	33,827
	10 20 30 40 50 60 MKKINKLAIV GGTHGNEFTG IYLVKKFEEF PELISRRNFD TQTLLANPQG FELVKRYIDT 70 80 90 100 110 120 DLNRCFKVED LENNTSLNYE ESRAKFINQM LGPKGNPKFD FILDLHTTTA NMGLTIILVN 130 140 150 160 170 180 YHPFNLKIAT YLSSVEPNLK IYTCFNPEVE NTFINSICER GFAIEVGPIA QGILQADLFY 190 200 210 220 230 240 KTEKLVQISL DFIEHFNEGK LDHINRDIVI YKHLKVVDYP KTKDGEIVAM IHPQLQGRDY 250 260 270 280 290 QKLSPGEPMF LTFDNQTIYY QEESPVWPVF INEAAYYEKG IAMCLTKKES IRV

References

[1]

"Complete sequence of Trichodesmium erythraeum IMS101." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IMS101.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000393 Genomic DNA. Translation: ABG53661.1.
RefSeq	YP_724134.1. NC_008312.1.
3D structure databases
ProteinModelPortal	Q10VR3.
ModBase	Search...
Protein-protein interaction databases
STRING	203124.Tery_4698.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABG53661; ABG53661; Tery_4698.
GeneID	4246352.
KEGG	ter:Tery_4698.
PATRIC	23995105. VBITriEry99848_5954.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2988.
HOGENOM	HOG000232489.
KO	K01437.
OMA	NFNEGKE.
ProtClustDB	PRK02259.
Family and domain databases
HAMAP	MF_00704. Aspartoacylase.
InterPro	IPR016708. Aspartoacylase. IPR007036. Aste_AspA. [Graphical view]
Pfam	PF04952. AstE_AspA. 1 hit. [Graphical view]
PIRSF	PIRSF018001. Aspartoacylase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ASPA_TRIEI

Accession

Primary (citable) accession number: Q10VR3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	August 22, 2006
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program