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Protein

Probable aspartoacylase

Gene

Tery_4698

Organism
Trichodesmium erythraeum (strain IMS101)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-acyl-L-aspartate + H2O = a carboxylate + L-aspartate.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi14 – 141ZincUniRule annotation
Metal bindingi17 – 171ZincUniRule annotation
Binding sitei56 – 561SubstrateUniRule annotation
Metal bindingi106 – 1061ZincUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Binding sitei276 – 2761SubstrateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciTERY203124:GJDR-4745-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable aspartoacylaseUniRule annotation (EC:3.5.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Tery_4698
OrganismiTrichodesmium erythraeum (strain IMS101)
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium
ProteomesiUP000008878 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Probable aspartoacylasePRO_1000147944Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi203124.Tery_4698.

Structurei

3D structure databases

ProteinModelPortaliQ10VR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni63 – 642Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the AspA/AstE family. Aspartoacylase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG2988.
HOGENOMiHOG000232489.
KOiK01437.
OMAiNFNEGKE.
OrthoDBiEOG6T4RX3.

Family and domain databases

HAMAPiMF_00704. Aspartoacylase.
InterProiIPR016708. Aspartoacylase.
IPR007036. Aste_AspA.
[Graphical view]
PfamiPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFiPIRSF018001. Aspartoacylase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10VR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKINKLAIV GGTHGNEFTG IYLVKKFEEF PELISRRNFD TQTLLANPQG
60 70 80 90 100
FELVKRYIDT DLNRCFKVED LENNTSLNYE ESRAKFINQM LGPKGNPKFD
110 120 130 140 150
FILDLHTTTA NMGLTIILVN YHPFNLKIAT YLSSVEPNLK IYTCFNPEVE
160 170 180 190 200
NTFINSICER GFAIEVGPIA QGILQADLFY KTEKLVQISL DFIEHFNEGK
210 220 230 240 250
LDHINRDIVI YKHLKVVDYP KTKDGEIVAM IHPQLQGRDY QKLSPGEPMF
260 270 280 290
LTFDNQTIYY QEESPVWPVF INEAAYYEKG IAMCLTKKES IRV
Length:293
Mass (Da):33,827
Last modified:August 22, 2006 - v1
Checksum:i114A67532CCB6C3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG53661.1.
RefSeqiWP_011613978.1. NC_008312.1.

Genome annotation databases

EnsemblBacteriaiABG53661; ABG53661; Tery_4698.
KEGGiter:Tery_4698.
PATRICi23995105. VBITriEry99848_5954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG53661.1.
RefSeqiWP_011613978.1. NC_008312.1.

3D structure databases

ProteinModelPortaliQ10VR3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203124.Tery_4698.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG53661; ABG53661; Tery_4698.
KEGGiter:Tery_4698.
PATRICi23995105. VBITriEry99848_5954.

Phylogenomic databases

eggNOGiCOG2988.
HOGENOMiHOG000232489.
KOiK01437.
OMAiNFNEGKE.
OrthoDBiEOG6T4RX3.

Enzyme and pathway databases

BioCyciTERY203124:GJDR-4745-MONOMER.

Family and domain databases

HAMAPiMF_00704. Aspartoacylase.
InterProiIPR016708. Aspartoacylase.
IPR007036. Aste_AspA.
[Graphical view]
PfamiPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFiPIRSF018001. Aspartoacylase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMS101.

Entry informationi

Entry nameiASPA_TRIEI
AccessioniPrimary (citable) accession number: Q10VR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: August 22, 2006
Last modified: July 22, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.