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Q10VH5 (UPPP_TRIEI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Tery_4798
OrganismTrichodesmium erythraeum (strain IMS101) [Complete proteome] [HAMAP]
Taxonomic identifier203124 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 312312Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290778

Regions

Transmembrane74 – 9421Helical; Potential
Transmembrane122 – 14221Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane226 – 24621Helical; Potential
Transmembrane254 – 27421Helical; Potential
Transmembrane288 – 30821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q10VH5 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 0B63925327F98F03

FASTA31233,897
        10         20         30         40         50         60 
MKFFCAFIFT ALIFISLEKI GQSCCPNPIV DSEQLTIFQA VILGMVQGVT ECIPVSSTAH 

        70         80         90        100        110        120 
LKIIPVALGW GDPGVAFTAV IQLGSIVSIV WYFWNDLTKI TFGAYKSIIT SDYQSPDLKM 

       130        140        150        160        170        180 
LVSIGLGTIP IVFFGLLIKV FIPDFDNSRL RSTVAIAIAS IIMALLLVIA ERIGSRKRNF 

       190        200        210        220        230        240 
EKLDIRDGIV IGLAQVLALI PGVSRSGSTI TGGLFIGLER STAARFSFLL GLPAITLAGL 

       250        260        270        280        290        300 
VELKTLLDEG FGSVGLVATL TGVFSAIIFS YIAISWLMRY LQTQDTWIFI WYRLAFGILI 

       310 
LIGIISGVIE NT 

« Hide

References

[1]"Complete sequence of Trichodesmium erythraeum IMS101."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IMS101.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000393 Genomic DNA. Translation: ABG53749.1.
RefSeqYP_724222.1. NC_008312.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING203124.Tery_4798.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG53749; ABG53749; Tery_4798.
GeneID4246452.
KEGGter:Tery_4798.
PATRIC23995361. VBITriEry99848_6082.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAVIYFRNE.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycTERY203124:GJDR-4845-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_TRIEI
AccessionPrimary (citable) accession number: Q10VH5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families