Reviewed, UniProtKB/Swiss-Prot Q10S72 (4CLL4_ORYSJ)

Names and origin

Protein names

Recommended name:
    4-coumarate--CoA ligase-like 4
    EC=6.2.1.-

Gene names

Name:	4CLL4
Ordered Locus Names:	Os03g0132000, LOC_Os03g04000

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 552	552	4-coumarate--CoA ligase-like 4		PRO_0000351630
Regions
	Nucleotide binding	207 – 215	9	ATP By similarity
	Nucleotide binding	347 – 352	6	ATP By similarity
	Region	279 – 346	68	SBD1
	Region	347 – 411	65	SBD2
Sites
	Binding site	432	1	ATP By similarity
	Binding site	447	1	ATP By similarity
	Binding site	538	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q10S72-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 808E31378514D299	FASTA	552	59,865
	10 20 30 40 50 60 MGRSPEMEVD ARSGYCAATR TFRSRRADVP LPADPEVDVV SFLASRRHSG VVALVDAATG 70 80 90 100 110 120 RRITFTELWR AVAGAASALA AHPVSLRKGH VALILSPNSV HFPVAALAAM SLGAVLTTAN 130 140 150 160 170 180 PLNTPAEIAK QVADARPVLA FTTRELLPKL PRAHDLRVVL LESARLPGDS SDPRIVATIE 190 200 210 220 230 240 EISATTPDPA RRKDRVTQDD PATLLYSSGT TGPSKGVVAT HRSLISMVQI IMTRFRLEGS 250 260 270 280 290 300 DKTETFLCTV PMFHVYGLVA FATGLLGCGA TVVVLSKYEL PEMLRSINAY GVTYLPLVPP 310 320 330 340 350 360 ILVAMVAHPK PLPLGQMRKV LSGGAPLGKE LIEGFREKYP QVEILQGYGL TESTAIGAST 370 380 390 400 410 420 DSAEESRRYG TAGLLSPNTE AKIVDPDSGE ALPVNRTGEL WIRGPYVMKG YFKNAEATQS 430 440 450 460 470 480 TLTPDGWLKT GDLCYIDEDG YLFVVDRLKE LIKYKGYQVP PAELEALLLT HPEVTDVAVI 490 500 510 520 530 540 PFPDREVGQF PMAYIVRKKG SNLSEREVME FVAKQVAPYK KVRKVAFVTD IPKNASGKIL 550 RKDLIKLATS KL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DP000009 Genomic DNA. Translation: ABF93822.1. AP008209 Genomic DNA. Translation: BAF10781.1. AK105769 mRNA. No translation available.
RefSeq	NP_001048867.1.
UniGene	Os.18327
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4331515.
KEGG	osa:4331515.
Family and domain databases
InterPro	IPR000873. AMP-dep_Synth/Lig. [Graphical view]
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL4_ORYSJ

Accession

Primary (citable) accession number: Q10S72

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	August 22, 2006
Last modified:	July 7, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)