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Protein

ATP phosphoribosyltransferase, chloroplastic

Gene

Os03g0134300

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).By similarity

Catalytic activityi

1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.

Cofactori

Mg2+By similarity

Enzyme regulationi

Feedback inhibited by histidine.By similarity

Pathwayi: L-histidine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate.
Proteins known to be involved in the 9 steps of the subpathway in this organism are:
  1. ATP phosphoribosyltransferase, chloroplastic (Os03g0134300)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Imidazoleglycerol-phosphate dehydratase (Os04g0617800), Imidazoleglycerol-phosphate dehydratase, Imidazoleglycerol-phosphate dehydratase
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. Histidinol dehydrogenase, chloroplastic (HDH)
This subpathway is part of the pathway L-histidine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate, the pathway L-histidine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Histidine biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00031; UER00006.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP phosphoribosyltransferase, chloroplastic (EC:2.4.2.17)
Short name:
ATP-PRTase
Short name:
AtATP-PRT
Gene namesi
Ordered Locus Names:Os03g0134300, LOC_Os03g04169
ORF Names:OJ1006F06.12, OJ1006F06.14
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 3

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 7272ChloroplastSequence analysisAdd
BLAST
Chaini73 – 404332ATP phosphoribosyltransferase, chloroplasticPRO_0000422875Add
BLAST

Proteomic databases

PaxDbiQ10S55.
PRIDEiQ10S55.

Expressioni

Gene expression databases

ExpressionAtlasiQ10S55. baseline and differential.
GenevisibleiQ10S55. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os03g04169.1.

Structurei

3D structure databases

ProteinModelPortaliQ10S55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG2831. Eukaryota.
COG0040. LUCA.
HOGENOMiHOG000223249.
InParanoidiQ10S55.
OMAiYVMMDYD.
OrthoDBiEOG09360FOJ.

Family and domain databases

Gene3Di3.30.70.120. 1 hit.
HAMAPiMF_00079. HisG_Long. 1 hit.
InterProiIPR013820. ATP_PRibTrfase_cat.
IPR018198. ATP_PRibTrfase_CS.
IPR001348. ATP_PRibTrfase_HisG.
IPR020621. ATP_PRibTrfase_HisG_long.
IPR013115. HisG_C.
IPR011322. N-reg_PII-like_a/b.
IPR015867. N-reg_PII/ATP_PRibTrfase_C.
[Graphical view]
PANTHERiPTHR21403. PTHR21403. 1 hit.
PfamiPF01634. HisG. 1 hit.
PF08029. HisG_C. 1 hit.
[Graphical view]
SUPFAMiSSF54913. SSF54913. 1 hit.
TIGRFAMsiTIGR00070. hisG. 1 hit.
TIGR03455. HisG_C-term. 1 hit.
PROSITEiPS01316. ATP_P_PHORIBOSYLTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10S55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPMLATLPD VTAVLHSPSA SPPSGLRAPA AVGMGMARTR FLAPRAAASA
60 70 80 90 100
ASAVSAKPAA VAPLYADRTV VRIGLPSKGR MSEQTLSLLK SCQLSVRHLN
110 120 130 140 150
PRQYTADIPQ VPNLEVWFQR PKDIVRKLQS GDLDLGIVGF DIVSEYGQGS
160 170 180 190 200
DDLVVVHDAL EFGHCRLSLA VPKEGIFENI NTLEDLANMP EWTQERPLRV
210 220 230 240 250
VTGFGYLGEK FMRENGFNHV SFLAGDGALE SYPAMGMADV IVDLVSSGTT
260 270 280 290 300
LRENNLKEID GGVVLESQAT LVACRRSLHK RNGVLEITHE MLERLEAHLT
310 320 330 340 350
ATGEIMVTAN MRGNSAEEVA ERVLSQTSLC GLQGPTISPV YRSRDGKVAV
360 370 380 390 400
EYYAINVVVP QKSLYKSIQQ LRSIGGSGVL VTKLTYIFDE ETPRWRKLLS

ELGL
Length:404
Mass (Da):43,909
Last modified:August 22, 2006 - v1
Checksum:iE999022A27D870ED
GO

Sequence cautioni

The sequence AAN05502 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence AAN05504 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099399 Genomic DNA. Translation: AAN05502.1. Sequence problems.
AC099399 Genomic DNA. Translation: AAN05504.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF93839.1.
AP008209 Genomic DNA. Translation: BAF10795.1.
AP014959 Genomic DNA. Translation: BAS82167.1.
RefSeqiXP_015631722.1. XM_015776236.1.
UniGeneiOs.8412.

Genome annotation databases

EnsemblPlantsiOS03T0134300-01; OS03T0134300-01; OS03G0134300.
GeneIDi4331530.
GrameneiOS03T0134300-01; OS03T0134300-01; OS03G0134300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099399 Genomic DNA. Translation: AAN05502.1. Sequence problems.
AC099399 Genomic DNA. Translation: AAN05504.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF93839.1.
AP008209 Genomic DNA. Translation: BAF10795.1.
AP014959 Genomic DNA. Translation: BAS82167.1.
RefSeqiXP_015631722.1. XM_015776236.1.
UniGeneiOs.8412.

3D structure databases

ProteinModelPortaliQ10S55.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os03g04169.1.

Proteomic databases

PaxDbiQ10S55.
PRIDEiQ10S55.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS03T0134300-01; OS03T0134300-01; OS03G0134300.
GeneIDi4331530.
GrameneiOS03T0134300-01; OS03T0134300-01; OS03G0134300.

Phylogenomic databases

eggNOGiKOG2831. Eukaryota.
COG0040. LUCA.
HOGENOMiHOG000223249.
InParanoidiQ10S55.
OMAiYVMMDYD.
OrthoDBiEOG09360FOJ.

Enzyme and pathway databases

UniPathwayiUPA00031; UER00006.

Gene expression databases

ExpressionAtlasiQ10S55. baseline and differential.
GenevisibleiQ10S55. OS.

Family and domain databases

Gene3Di3.30.70.120. 1 hit.
HAMAPiMF_00079. HisG_Long. 1 hit.
InterProiIPR013820. ATP_PRibTrfase_cat.
IPR018198. ATP_PRibTrfase_CS.
IPR001348. ATP_PRibTrfase_HisG.
IPR020621. ATP_PRibTrfase_HisG_long.
IPR013115. HisG_C.
IPR011322. N-reg_PII-like_a/b.
IPR015867. N-reg_PII/ATP_PRibTrfase_C.
[Graphical view]
PANTHERiPTHR21403. PTHR21403. 1 hit.
PfamiPF01634. HisG. 1 hit.
PF08029. HisG_C. 1 hit.
[Graphical view]
SUPFAMiSSF54913. SSF54913. 1 hit.
TIGRFAMsiTIGR00070. hisG. 1 hit.
TIGR03455. HisG_C-term. 1 hit.
PROSITEiPS01316. ATP_P_PHORIBOSYLTR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHIS1_ORYSJ
AccessioniPrimary (citable) accession number: Q10S55
Secondary accession number(s): A0A0P0VSR1, Q8H8D1, Q8H8D3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2013
Last sequence update: August 22, 2006
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.