Q10QL5 (BIP2C_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C BIPP2C1
EC=3.1.3.16

Alternative name(s):
BTH-induced protein phosphatase 2C 1
Short name=OsBIPP2C1

Gene names

Name:	BIPP2C1
Ordered Locus Names:	Os03g0192500, LOC_Os03g09220

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	569 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May play a role in responses to biotic and abiotic stresses By similarity.
Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence ABF94414.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q10QL5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q10QL5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: MDEEARAAGC...ELCLCSPTGV → MKRRAPPDAP...LVWFGVGLDA

Note: Derived from EST data. No experimental confirmation available.

Isoform 3 (identifier: Q10QL5-3)

The sequence of this isoform differs from the canonical sequence as follows:
     35-36: Missing.

Note: Derived from EST data. May be due to a competing donor splice site. No experimental confirmation available.

Isoform 4 (identifier: Q10QL5-4)

The sequence of this isoform differs from the canonical sequence as follows:
     121-256: Missing.

Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 569	569	Probable protein phosphatase 2C BIPP2C1		PRO_0000363327
Regions
	Domain	327 – 564	238	PP2C-like
Sites
	Metal binding	358	1	Manganese 1 By similarity
	Metal binding	358	1	Manganese 2 By similarity
	Metal binding	359	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	488	1	Manganese 2 By similarity
	Metal binding	555	1	Manganese 2 By similarity
Natural variations
	Alternative sequence	1 – 36	36	MDEEA…SPTGV → MKRRAPPDAPQRRPARRLLP VALPPSSASAPLQVWVRGIH ACLISFGFGSRFDLVLVWFG VGLDA in isoform 2.		VSP_036286
	Alternative sequence	35 – 36	2	Missing in isoform 3.		VSP_036287
	Alternative sequence	121 – 256	136	Missing in isoform 4.		VSP_036288

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 5ACFAA6EB5E5254E	FASTA	569	58,800
	10 20 30 40 50 60 MDEEARAAGC SPAPPRAPAA SCGAAAELCL CSPTGVEGIE QVPGCPCFED AGAVVVSGEA 70 80 90 100 110 120 PEGPGVLCSE DGAELKLAEQ GALDVRLGSP AVGIHEQQLL HRGTSGSDEA GAINEISPVE 130 140 150 160 170 180 VSPSEASSNL DTAGAIGGSP LMLESLPETS DTRGCEQEVM PGVVVGSSNR DASSEVGVES 190 200 210 220 230 240 ERGSDADGRN GLGEGELVSS VDGGGAEKSS KVTGVLSEEG VDGMETALEP CVASVGSITQ 250 260 270 280 290 300 VEEGVDRMET SLDDSEASDG STTQDFDTDV ETESSGSSIE EQDMGYGVHI PHTEQAICEV 310 320 330 340 350 360 ARGNKSSEVK SSDRMSSVTL PTLILASGAA MLPHPSKVLT GGEDAYFIAC DGWFGVADGV 370 380 390 400 410 420 GQWSFEGINA GLYARELMDG CKKAVMESQG APEMRTEEVL AKAADEARSP GSSTVLVAHF 430 440 450 460 470 480 DGQVLHACNI GDSGFLVIRN GEIYQKSKPM TYGFNFPLQI EKGDDPFKLV QKYTIDLQEG 490 500 510 520 530 540 DAIVTATDGL FDNVYEEEIA AVISKSLEAG LKPSEIAEFL VARAKEVGRS ATCRSPFSDA 550 560 ALAVGYLGYS GGKLDDVTVV VSVVRKSEV
	Isoform 2 [UniParc]. Checksum: 19BF1BFCE7F33A60	FASTA	598	62,490
	10 20 30 40 50 60 MKRRAPPDAP QRRPARRLLP VALPPSSASA PLQVWVRGIH ACLISFGFGS RFDLVLVWFG 70 80 90 100 110 120 VGLDAEGIEQ VPGCPCFEDA GAVVVSGEAP EGPGVLCSED GAELKLAEQG ALDVRLGSPA 130 140 150 160 170 180 VGIHEQQLLH RGTSGSDEAG AINEISPVEV SPSEASSNLD TAGAIGGSPL MLESLPETSD 190 200 210 220 230 240 TRGCEQEVMP GVVVGSSNRD ASSEVGVESE RGSDADGRNG LGEGELVSSV DGGGAEKSSK 250 260 270 280 290 300 VTGVLSEEGV DGMETALEPC VASVGSITQV EEGVDRMETS LDDSEASDGS TTQDFDTDVE 310 320 330 340 350 360 TESSGSSIEE QDMGYGVHIP HTEQAICEVA RGNKSSEVKS SDRMSSVTLP TLILASGAAM 370 380 390 400 410 420 LPHPSKVLTG GEDAYFIACD GWFGVADGVG QWSFEGINAG LYARELMDGC KKAVMESQGA 430 440 450 460 470 480 PEMRTEEVLA KAADEARSPG SSTVLVAHFD GQVLHACNIG DSGFLVIRNG EIYQKSKPMT 490 500 510 520 530 540 YGFNFPLQIE KGDDPFKLVQ KYTIDLQEGD AIVTATDGLF DNVYEEEIAA VISKSLEAGL 550 560 570 580 590 KPSEIAEFLV ARAKEVGRSA TCRSPFSDAA LAVGYLGYSG GKLDDVTVVV SVVRKSEV
	Isoform 3 [UniParc]. Checksum: D7A97971D46CBF73	FASTA	567	58,644
	10 20 30 40 50 60 MDEEARAAGC SPAPPRAPAA SCGAAAELCL CSPTEGIEQV PGCPCFEDAG AVVVSGEAPE 70 80 90 100 110 120 GPGVLCSEDG AELKLAEQGA LDVRLGSPAV GIHEQQLLHR GTSGSDEAGA INEISPVEVS 130 140 150 160 170 180 PSEASSNLDT AGAIGGSPLM LESLPETSDT RGCEQEVMPG VVVGSSNRDA SSEVGVESER 190 200 210 220 230 240 GSDADGRNGL GEGELVSSVD GGGAEKSSKV TGVLSEEGVD GMETALEPCV ASVGSITQVE 250 260 270 280 290 300 EGVDRMETSL DDSEASDGST TQDFDTDVET ESSGSSIEEQ DMGYGVHIPH TEQAICEVAR 310 320 330 340 350 360 GNKSSEVKSS DRMSSVTLPT LILASGAAML PHPSKVLTGG EDAYFIACDG WFGVADGVGQ 370 380 390 400 410 420 WSFEGINAGL YARELMDGCK KAVMESQGAP EMRTEEVLAK AADEARSPGS STVLVAHFDG 430 440 450 460 470 480 QVLHACNIGD SGFLVIRNGE IYQKSKPMTY GFNFPLQIEK GDDPFKLVQK YTIDLQEGDA 490 500 510 520 530 540 IVTATDGLFD NVYEEEIAAV ISKSLEAGLK PSEIAEFLVA RAKEVGRSAT CRSPFSDAAL 550 560 AVGYLGYSGG KLDDVTVVVS VVRKSEV
	Isoform 4 [UniParc]. Checksum: F5C3792963532A86	FASTA	433	45,179
	10 20 30 40 50 60 MDEEARAAGC SPAPPRAPAA SCGAAAELCL CSPTGVEGIE QVPGCPCFED AGAVVVSGEA 70 80 90 100 110 120 PEGPGVLCSE DGAELKLAEQ GALDVRLGSP AVGIHEQQLL HRGTSGSDEA GAINEISPVE 130 140 150 160 170 180 ASDGSTTQDF DTDVETESSG SSIEEQDMGY GVHIPHTEQA ICEVARGNKS SEVKSSDRMS 190 200 210 220 230 240 SVTLPTLILA SGAAMLPHPS KVLTGGEDAY FIACDGWFGV ADGVGQWSFE GINAGLYARE 250 260 270 280 290 300 LMDGCKKAVM ESQGAPEMRT EEVLAKAADE ARSPGSSTVL VAHFDGQVLH ACNIGDSGFL 310 320 330 340 350 360 VIRNGEIYQK SKPMTYGFNF PLQIEKGDDP FKLVQKYTID LQEGDAIVTA TDGLFDNVYE 370 380 390 400 410 420 EEIAAVISKS LEAGLKPSEI AEFLVARAKE VGRSATCRSP FSDAALAVGY LGYSGGKLDD 430 VTVVVSVVRK SEV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DP000009 Genomic DNA. Translation: ABF94412.1. DP000009 Genomic DNA. Translation: ABF94413.1. DP000009 Genomic DNA. Translation: ABF94414.1. Sequence problems. DP000009 Genomic DNA. Translation: ABF94415.1. DP000009 Genomic DNA. Translation: ABF94416.1. AP008209 Genomic DNA. Translation: BAF11154.1. AK068957 mRNA. Translation: BAG91182.1.
RefSeq	NP_001049240.1. NM_001055775.1.
UniGene	Os.7974.
3D structure databases
ProteinModelPortal	Q10QL5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g09220.2; LOC_Os03g09220.2; LOC_Os03g09220.
GeneID	4331915.
KEGG	osa:4331915.
Organism-specific databases
Gramene	Q10QL5.
Phylogenomic databases
eggNOG	COG0631.
OMA	EEGVDRM.
ProtClustDB	CLSN2693629.
Gene expression databases
ArrayExpress	Q10QL5.
Family and domain databases
Gene3D	3.60.40.10. 2 hits.
InterPro	IPR001932. PP2C-like. [Graphical view]
Pfam	PF07228. SpoIIE. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BIP2C_ORYSJ

Accession

Primary (citable) accession number: Q10QL5
Secondary accession number(s): Q10QL1 , Q10QL2, Q10QL3, Q10QL4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	August 22, 2006
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program