MADS-box transcription factor 1 - Oryza sativa subsp. japonica (Rice)

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Q10PZ9 (MADS1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
MADS-box transcription factor 1

Alternative name(s):
OsMADS1
Protein LEAFY HULL STERILE 1
Protein SEPALLATA-like

Gene names

Name:	MADS1
Synonyms:	LHS1
Ordered Locus Names:	Os03g0215400, LOC_Os03g11614

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probable transcription factor involved in the development of floral organs. Required for the formation of inner floral organs (lodicules, stamens and carpels, or whorls 2, 3 and 4) and the lemma and palea (whorl 1), which are grass floral organs analogous to sepals. May be involved in the control of flowering time. Seems to act as transcriptional activator. May act upstream of the auxin-responsive protein GH3.8. Ref.1 Ref.2 Ref.8 Ref.9 Ref.10
Subunit structure	May interact with the K-box of MADS6, MADS14 and MADS15.
Subcellular location	Nucleus Probable.
Tissue specificity	Expressed in lemmas, paleas and pistils. Weakly expressed in carpels. Ref.1
Developmental stage	Expressed at early stage of flower development in floral meristem, and at later stage in lemma, palea and carpel primordia. Ref.9
Disruption phenotype	Homeotic transformation of lodicules, stamens and carpels into lemma- and palea-like structures. Ref.2
Sequence similarities	Contains 1 K-box domain. Contains 1 MADS-box domain.

Ontologies

Keywords
Biological process	Differentiation Flowering Transcription Transcription regulation
Cellular component	Nucleus
Ligand	DNA-binding
Molecular function	Activator Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell differentiation Inferred from electronic annotation. Source: UniProtKB-KW flower development Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct
MADS14	Q10CQ1	4	EBI-627957,EBI-627890
MADS15	Q6Q9I2	4	EBI-627957,EBI-627918
MADS6	Q6EU39	4	EBI-627957,EBI-627980

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 257

257

MADS-box transcription factor 1

PRO_0000229892

Regions

Domain

1 – 61

MADS-box

Domain

85 – 175

K-box

Compositional bias

200 – 251

His-rich

Experimental info

Mutagenesis

R → C in lhs1; abnormal growth of spikelets and sterile flowers; when associated with D-27. Ref.2

Mutagenesis

G → D in lhs1; abnormal growth of spikelets and sterile flowers; when associated with C-24. Ref.2

Sequences

Sequence

Length

Mass (Da)

Tools

Q10PZ9 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 70A3DAEED355A37C
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FASTA

257

29,528

        10         20         30         40         50         60 
MGRGKVELKR IENKISRQVT FAKRRNGLLK KAYELSLLCD AEVALIIFSG RGRLFEFSSS 

        70         80         90        100        110        120 
SCMYKTLERY RSCNYNSQDA AAPENEINYQ EYLKLKTRVE FLQTTQRNIL GEDLGPLSMK 

       130        140        150        160        170        180 
ELEQLENQIE VSLKQIRSRK NQALLDQLFD LKSKEQQLQD LNKDLRKKLQ ETSAENVLHM 

       190        200        210        220        230        240 
SWQDGGGHSG SSTVLADQPH HHQGLLHPHP DQGDHSLQIG YHHPHAHHHQ AYMDHLSNEA 

       250 
ADMVAHHPNE HIPSGWI

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Early flowering and reduced apical dominance result from ectopic expression of a rice MADS box gene." Chung Y.-Y., Kim S.-R., Finkel D., Yanofsky M.F., An G. Plant Mol. Biol. 26:657-665(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY. Tissue: Flower.
[2]	"Leafy hull sterile1 is a homeotic mutation in a rice MADS box gene affecting rice flower development." Jeon J.-S., Jang S., Lee S., Nam J., Kim C., Lee S.-H., Chung Y.-Y., Kim S.-R., Lee Y.H., Cho Y.-G., An G. Plant Cell 12:871-884(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, DISRUPTION PHENOTYPE, MUTAGENESIS OF ARG-24 AND GLY-27.
[3]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. Jackson S. Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[5]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[6]	"Determination of the motif responsible for interaction between the rice APETALA1/AGAMOUS-LIKE9 family proteins using a yeast two-hybrid system." Moon Y.-H., Kang H.-G., Jung J.-Y., Jeon J.-S., Sung S.-K., An G. Plant Physiol. 120:1193-1204(1999) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH MADS6.
[7]	"Two rice MADS domain proteins interact with OsMADS1." Lim J., Moon Y.-H., An G., Jang S.K. Plant Mol. Biol. 44:513-527(2000) [PubMed] [Europe PMC] [Abstract] Cited for: TRANSCRIPTIONAL ACTIVATOR, INTERACTION WITH MADS14 AND MADS15.
[8]	"Production of transgenic rice plants showing reduced heading date and plant height by ectopic expression of rice MADS-box genes." Jeon J.-S., Lee S., Nam J., Jung K.-H., Yang W.-S., Yi G.-H., Oh B.-G., An G. Mol. Breed. 6:581-592(2000) [AGRICOLA] [Europe PMC] Cited for: FUNCTION.
[9]	"Ectopic expression of rice OsMADS1 reveals a role in specifying the lemma and palea, grass floral organs analogous to sepals." Prasad K., Sriram P., Kumar C.S., Kushalappa K., Vijayraghavan U. Dev. Genes Evol. 211:281-290(2001) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, DEVELOPMENTAL STAGE.
[10]	"Conservation of the E-function for floral organ identity in rice revealed by the analysis of tissue culture-induced loss-of-function mutants of the OsMADS1 gene." Agrawal G.K., Abe K., Yamazaki M., Miyao A., Hirochika H. Plant Mol. Biol. 59:125-135(2005) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L34271 mRNA. Translation: AAA66187.1. AF204063 Genomic DNA. Translation: AAG35652.1. AC105732 Genomic DNA. No translation available. AC135158 Genomic DNA. No translation available. DP000009 Genomic DNA. Translation: ABF94637.1. AP008209 Genomic DNA. Translation: BAF11290.1.
PIR	S53306.
RefSeq	NP_001049376.1. NM_001055911.1.
UniGene	Os.10941.
3D structure databases
ProteinModelPortal	Q10PZ9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q10PZ9. 4 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g11614.1; LOC_Os03g11614.1; LOC_Os03g11614.
GeneID	4332059.
KEGG	osa:4332059.
Organism-specific databases
Gramene	Q10PZ9.
Phylogenomic databases
eggNOG	COG5068.
OMA	SSSCMYK.
ProtClustDB	CLSN2693669.
Gene expression databases
ArrayExpress	Q10PZ9.
Family and domain databases
InterPro	IPR002487. TF_Kbox. IPR002100. TF_MADSbox. [Graphical view]
Pfam	PF01486. K-box. 1 hit. PF00319. SRF-TF. 1 hit. [Graphical view]
PRINTS	PR00404. MADSDOMAIN.
SMART	SM00432. MADS. 1 hit. [Graphical view]
SUPFAM	SSF55455. TF_MADSbox. 1 hit.
PROSITE	PS51297. K_BOX. 1 hit. PS00350. MADS_BOX_1. 1 hit. PS50066. MADS_BOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MADS1_ORYSJ

Accession

Primary (citable) accession number: Q10PZ9
Secondary accession number(s): Q3ZES6, Q40700

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	August 22, 2006
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Sequence annotation (Features)

Molecule processing

Regions

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents