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Q10P01 (LCB1A_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Long chain base biosynthesis protein 1a

EC=2.3.1.50
Gene names
Ordered Locus Names:Os03g0252800, LOC_Os03g14800
ORF Names:OsJ_10166
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core By similarity.

Catalytic activity

Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Lipid metabolism; sphingolipid metabolism.

Subunit structure

Heterodimer with LCB2. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1 and LCB2 By similarity.

Subcellular location

Endoplasmic reticulum membrane; Single-pass membrane protein By similarity.

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Sequence caution

The sequence ABF95003.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence ABF95004.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence ABF95005.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 485485Long chain base biosynthesis protein 1a
PRO_0000419147

Regions

Transmembrane32 – 5221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q10P01 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: CC3E17D2310E76CF

FASTA48552,426
        10         20         30         40         50         60 
MDMALPIVNA TAAVLARVSA AFNAPFARAV VFGVHIDGHL VVEGLLIAVI VFQLSRKSYK 

        70         80         90        100        110        120 
PPKKPLSEKE IDELCDEWEP EPLCPPIKDG ARIDTPMLES AAAPHTTIDG KEVINFASAN 

       130        140        150        160        170        180 
YLGLIGNEKI IDSCVGSLEK YGVGSCGPRG FYGTIDVHLD CEAKIAKFLG TPDSILYSYG 

       190        200        210        220        230        240 
ISTIFSVIPA FCKKGDIIVA DEGVHWAVQN GLHLSRSTVV YFKHNDMASL ANTLEKLTRG 

       250        260        270        280        290        300 
NKRAEKIRRY IVVESIYQNS GQIAPLDEIV RLKEKYRFRV ILEESHSFGV LGQSGRGLAE 

       310        320        330        340        350        360 
HYGVPIDKID IITAGMGNAL ATDGGFCTGS VRVVDHQRLS SSGYVFSASL PPYLASAAVS 

       370        380        390        400        410        420 
AVSYLEGNPS VLADLRSNIS FLHKELSGTP GLEISSHVLS PIVFLKLKKS TGSSNTDIDL 

       430        440        450        460        470        480 
LETIAERVLK EDSVFIVASK RSPLDRCKLP VGIRLFMSAG HTDSDISKVS SSLKRVSASV 


LSDYI 

« Hide

References

« Hide 'large scale' references
[1]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DP000009 Genomic DNA. Translation: ABF95002.1.
DP000009 Genomic DNA. Translation: ABF95003.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF95004.1. Sequence problems.
DP000009 Genomic DNA. Translation: ABF95005.1. Sequence problems.
AP008209 Genomic DNA. Translation: BAF11490.1.
CM000140 Genomic DNA. Translation: EAZ26297.1.
AK065537 mRNA. Translation: BAG89556.1.
AK067765 mRNA. Translation: BAG90585.1.
RefSeqNP_001049576.1. NM_001056111.1.
UniGeneOs.8513.

3D structure databases

ProteinModelPortalQ10P01.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39946.BGIOSIBCE010384.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS03T0252800-01; OS03T0252800-01; OS03G0252800.
GeneID4332274.
KEGGosa:4332274.

Organism-specific databases

GrameneQ10P01.

Phylogenomic databases

eggNOGCOG0156.
HOGENOMHOG000216602.
KOK00654.

Enzyme and pathway databases

UniPathwayUPA00222.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLCB1A_ORYSJ
AccessionPrimary (citable) accession number: Q10P01
Secondary accession number(s): Q10P00, Q10P02
Entry history
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways