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Protein

Laccase-10

Gene

LAC10

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi87Copper 1By similarity1
Metal bindingi89Copper 2By similarity1
Metal bindingi132Copper 2By similarity1
Metal bindingi134Copper 3By similarity1
Metal bindingi479Copper 4By similarity1
Metal bindingi482Copper 1By similarity1
Metal bindingi484Copper 3By similarity1
Metal bindingi541Copper 3By similarity1
Metal bindingi542Copper 4By similarity1
Metal bindingi543Copper 2By similarity1
Metal bindingi547Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-10 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 10
Diphenol oxidase 10
Urishiol oxidase 10
Gene namesi
Name:LAC10
Ordered Locus Names:Os03g0273200, LOC_Os03g16610
ORF Names:OsJ_009911, OsJ_10313Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000029189530 – 578Laccase-10Add BLAST549

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi42N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi119N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi192N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi208N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi244N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi307N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi336N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi384N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi392N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi402N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi438N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi445N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi448N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi451N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi461N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ10ND7

Expressioni

Gene expression databases

ExpressionAtlasiQ10ND7 baseline and differential
GenevisibleiQ10ND7 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os03g16610.1

Structurei

3D structure databases

SMRiQ10ND7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 153Plastocyanin-like 1Add BLAST117
Domaini163 – 319Plastocyanin-like 2Add BLAST157
Domaini428 – 562Plastocyanin-like 3Add BLAST135

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
HOGENOMiHOG000241916
InParanoidiQ10ND7
KOiK05909
OMAiPEQKLMP
OrthoDBiEOG093606WG

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
cd13897 CuRO_3_LCC_plant, 1 hit
Gene3Di2.60.40.4203 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR034289 CuRO_3_LCC
IPR017761 Laccase
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 3 hits
TIGRFAMsiTIGR03389 laccase, 1 hit
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10ND7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARCLALLL LYGTLLLLLL LPQLPLAGAA TRYYTFNVKL QNVTRLCNTR
60 70 80 90 100
AIPTVNGKFP GPKIVTREGD RVVVKVVNNI KDNITIHWHG VRQMRTGWSD
110 120 130 140 150
GPAYVTQCPI QTGQSYVYNF TINGQRGTLF WHAHVSWLRS TLYGPIIILP
160 170 180 190 200
KAGLPLPFTE PHKDVPIIFG EWFNADPEAI VAQALQTGGG PNVSDAYTIN
210 220 230 240 250
GLPGPLYNCS SKDTFRLKVQ PGKMYLLRLI NAALNDELFF SVANHTLTVV
260 270 280 290 300
DVDASYVKPF DTDVVLITPG QTTNVLLRAK PTAEAAGATH LMMARPYATG
310 320 330 340 350
RPGTYDNTTV AAVLEYAPPG HIKSLPLLRP SLPALNDTAF AAGFAAKLRS
360 370 380 390 400
LACPDYPSNV PRRVDKPFFF AVGLGTTPCP GSNNQTCQGP TNTTKFTASI
410 420 430 440 450
NNVSFDMPTT ALLQAHYTGQ SAGVYTADFP ASPLEPFNYT GTPPNNTNVS
460 470 480 490 500
NGTRVVVLPY NASVEVVLQD TSILGAESHP LHLHGFDFFV VGQGTGNYDP
510 520 530 540 550
SKHPAEFNLV DPVQRNTVGV PAGGWVAIRF FADNPGVWFM HCHLEVHTTW
560 570
GLKMAWVVND GPLPEQKLMP PPSDLPMC
Length:578
Mass (Da):62,829
Last modified:August 22, 2006 - v1
Checksum:i4493AA05FF1E36D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000009 Genomic DNA Translation: ABF95230.1
AP008209 Genomic DNA Translation: BAF11613.1
AP014959 Genomic DNA Translation: BAS83490.1
CM000140 Genomic DNA Translation: EEE58784.1
AK060579 mRNA Translation: BAG87502.1
AK072397 mRNA Translation: BAG92951.1
RefSeqiXP_015628787.1, XM_015773301.1
UniGeneiOs.5638

Genome annotation databases

EnsemblPlantsiOs03t0273200-01; Os03t0273200-01; Os03g0273200
Os03t0273200-02; Os03t0273200-02; Os03g0273200
GeneIDi4332400
GrameneiOs03t0273200-01; Os03t0273200-01; Os03g0273200
Os03t0273200-02; Os03t0273200-02; Os03g0273200
KEGGiosa:4332400

Similar proteinsi

Entry informationi

Entry nameiLAC10_ORYSJ
AccessioniPrimary (citable) accession number: Q10ND7
Secondary accession number(s): A3AGI9, B7E555
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: August 22, 2006
Last modified: February 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome