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Q10LR9 (DCUP2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uroporphyrinogen decarboxylase 2, chloroplastic
Short name=UPD2
Short name=URO-D2
EC=4.1.1.37
Gene names
Ordered Locus Names:Os03g0337600, LOC_Os03g21900
ORF Names:OsJ_10762
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III By similarity.

Catalytic activity

Uroporphyrinogen III = coproporphyrinogen + 4 CO2.

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Subunit structure

Homodimer By similarity.

Subcellular location

Plastid › chloroplast Probable.

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Ontologies

Keywords
   Biological processChlorophyll biosynthesis
Porphyrin biosynthesis
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   Molecular functionDecarboxylase
Lyase
Gene Ontology (GO)
   Biological processchlorophyll biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionuroporphyrinogen decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3030Chloroplast Potential
Chain31 – 390360Uroporphyrinogen decarboxylase 2, chloroplastic
PRO_0000376073

Regions

Region70 – 745Substrate binding By similarity

Sites

Binding site891Substrate By similarity
Binding site1191Substrate By similarity
Binding site1201Substrate By similarity
Binding site1971Substrate By similarity
Binding site2521Substrate By similarity
Binding site3671Substrate By similarity
Site1201Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q10LR9 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 5C0E30F10B23716C

FASTA39042,844
        10         20         30         40         50         60 
MATACPPLSL QPAYLSGRSA RARRPPPAVR CSAVGEVMAE TAAVGTAEEP LLVSAIKGRK 

        70         80         90        100        110        120 
VERPPVWLMR QAGRYMKSYQ LLCERHPSFR ERSENVDLVV EISLQPWKVF KPDGVILFSD 

       130        140        150        160        170        180 
ILTPLPGMNI PFDIVKGKGP VIFDPLRTAA AVNEVREFVP EEWVPYVGQA LNILREEVNN 

       190        200        210        220        230        240 
EAAVLGFVGA PFTLASYCVE GGSSKNFSKI KKMAFSEPEI LHNLLQKFTT SMANYIKYQA 

       250        260        270        280        290        300 
DNGAQAVQIF DSWATELSPV DFEEFSLPYL KQIVDSVKET HPELPLILYA SGSGGLLERL 

       310        320        330        340        350        360 
PLTGVDVVSL DWTVDMAEGR KRLGSNIAVQ GNVDPGVLFG SKEFISKRIF DTVQKAGNSG 

       370        380        390 
HVLNLGHGIK VGTPEENVAH FFEVAKGIRY

« Hide

References

« Hide 'large scale' references
[1]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed: 12869764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DP000009 Genomic DNA. Translation: ABF95829.1.
AP008209 Genomic DNA. Translation: BAF11963.1.
CM000140 Genomic DNA. Translation: EEE59019.1.
RefSeqNP_001050049.1. NM_001056584.1.
UniGeneOs.10800.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ10LR9.

Proteomic databases

PRIDEQ10LR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os03g21900.1; LOC_Os03g21900.1; LOC_Os03g21900.
GeneID4332771.
KEGGosa:4332771.

Phylogenomic databases

GeneTreeEPGT00070000030662.
HOGENOMHBG628392.
OMAGMNIPFD.
PhylomeDBQ10LR9.
ProtClustDBPLN02433.

Family and domain databases

InterProIPR006361. Uroporphyrinogen_deCO2ase_HemE.
IPR000257. Uroporphyrinogen_deCOase.
[Graphical view]
KOK01599.
PANTHERPTHR21091:SF2. HemE. 1 hit.
PfamPF01208. URO-D. 1 hit.
[Graphical view]
TIGRFAMsTIGR01464. HemE. 1 hit.
PROSITEPS00906. UROD_1. 1 hit.
PS00907. UROD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDCUP2_ORYSJ
AccessionPrimary (citable) accession number: Q10LR9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: August 22, 2006
Last modified: November 16, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents