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Protein

1-aminocyclopropane-1-carboxylate synthase 1

Gene

ACC1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.

Catalytic activityi

S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine.

Cofactori

Pathwayi: ethylene biosynthesis via S-adenosyl-L-methionine

This protein is involved in step 1 of the subpathway that synthesizes ethylene from S-adenosyl-L-methionine.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. 1-aminocyclopropane-1-carboxylate synthase 1 (ACC1)
  2. 1-aminocyclopropane-1-carboxylate oxidase 1 (ACO1)
This subpathway is part of the pathway ethylene biosynthesis via S-adenosyl-L-methionine, which is itself part of Alkene biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes ethylene from S-adenosyl-L-methionine, the pathway ethylene biosynthesis via S-adenosyl-L-methionine and in Alkene biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processEthylene biosynthesis, Fruit ripening
LigandPyridoxal phosphate, S-adenosyl-L-methionine

Enzyme and pathway databases

BRENDAi4.4.1.14. 4460.
UniPathwayiUPA00384; UER00562.

Names & Taxonomyi

Protein namesi
Recommended name:
1-aminocyclopropane-1-carboxylate synthase 1 (EC:4.4.1.14)
Short name:
ACC synthase 1
Alternative name(s):
S-adenosyl-L-methionine methylthioadenosine-lyase 1
Gene namesi
Name:ACC1
Ordered Locus Names:Os03g0727600, LOC_Os03g51740
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001239161 – 4871-aminocyclopropane-1-carboxylate synthase 1Add BLAST487

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei286N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiQ10DK7.

Expressioni

Gene expression databases

GenevisibleiQ10DK7. OS.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi39947.LOC_Os03g51740.1.

Structurei

3D structure databases

ProteinModelPortaliQ10DK7.
SMRiQ10DK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0256. Eukaryota.
COG0436. LUCA.
KOiK01762.
OMAiPYYGAIT.
OrthoDBiEOG093608EZ.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiView protein in InterPro
IPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_sub2.
PfamiView protein in Pfam
PF00155. Aminotran_1_2. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiView protein in PROSITE
PS00105. AA_TRANSFER_CLASS_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10DK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSQVVAEEK PQLLSKKAGC NSHGQDSSYF LGWQEYEKNP FDPVSNPSGI
60 70 80 90 100
IQMGLAENQL SFDLLEEWLE KNPHALGLRR EGGGASVFRE LALFQDYHGL
110 120 130 140 150
PAFKNALARF MSEQRGYKVV FDPSNIVLTA GATSANEALM FCLADHGDAF
160 170 180 190 200
LIPTPYYPGF DRDLKWRTGA EIVPVHCASA NGFRVTRPAL DDAYRRAQKR
210 220 230 240 250
RLRVKGVLIT NPSNPLGTAS PRADLETIVD FVAAKGIHLI SDEIYAGTAF
260 270 280 290 300
AEPPAGFVSA LEVVAGRDGG GADVSDRVHV VYSLSKDLGL PGFRVGAIYS
310 320 330 340 350
ANAAVVSAAT KMSSFGLVSS QTQYLLAALL GDRDFTRSYV AENKRRIKER
360 370 380 390 400
HDQLVDGLRE IGIGCLPSNA GLFCWVDMSH LMRSRSFAGE MELWKKVVFE
410 420 430 440 450
VGLNISPGSS CHCREPGWFR VCFANMSAKT LDVAMQRLRS FVDSATGGGD
460 470 480
NAALRRAAVP VRSVSCPLAI KWALRLTPSI ADRKAER
Length:487
Mass (Da):53,139
Last modified:August 22, 2006 - v1
Checksum:i561D262125D7759E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135956 Genomic DNA. Translation: AAT77071.1.
DP000009 Genomic DNA. Translation: ABF98659.1.
AP008209 Genomic DNA. Translation: BAF13056.1.
AP014959 Genomic DNA. Translation: BAS86187.1.
AK071011 mRNA. Translation: BAG92257.1.
RefSeqiXP_015629245.1. XM_015773759.1.
UniGeneiOs.53146.

Genome annotation databases

EnsemblPlantsiOS03T0727600-01; OS03T0727600-01; OS03G0727600.
GeneIDi4333976.
GrameneiOS03T0727600-01; OS03T0727600-01; OS03G0727600.
KEGGiosa:4333976.

Similar proteinsi

Entry informationi

Entry namei1A11_ORYSJ
AccessioniPrimary (citable) accession number: Q10DK7
Secondary accession number(s): B7EIR0, Q07215, Q6ATI2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: August 22, 2006
Last modified: August 30, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families