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Protein

Putative acid phosphatase 5

Gene

pho-5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei40NucleophileBy similarity1
Active sitei279Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

ReactomeiR-CEL-1483166 Synthesis of PA

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acid phosphatase 5 (EC:3.1.3.2)
Gene namesi
Name:pho-5
ORF Names:B0361.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiB0361.7 ; CE32100 ; WBGene00015161 ; pho-5

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 13Sequence analysisAdd BLAST13
ChainiPRO_000002396814 – 422Putative acid phosphatase 5Add BLAST409

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi104N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi152 ↔ 363By similarity
Disulfide bondi205 ↔ 302By similarity
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi218N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi312N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi323N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi338 ↔ 342By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

EPDiQ10944
PaxDbiQ10944
PeptideAtlasiQ10944

PTM databases

iPTMnetiQ10944

Expressioni

Gene expression databases

BgeeiWBGene00015161

Interactioni

Protein-protein interaction databases

STRINGi6239.B0361.7

Structurei

3D structure databases

ProteinModelPortaliQ10944
SMRiQ10944
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG3720 Eukaryota
ENOG410ZVBQ LUCA
GeneTreeiENSGT00530000062956
HOGENOMiHOG000020614
InParanoidiQ10944
OMAiYGIHKQK
OrthoDBiEOG091G09FA
PhylomeDBiQ10944

Family and domain databases

CDDicd07061 HP_HAP_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR033379 Acid_Pase_AS
IPR000560 His_Pase_clade-2
IPR029033 His_PPase_superfam
PfamiView protein in Pfam
PF00328 His_Phos_2, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
PROSITEiView protein in PROSITE
PS00616 HIS_ACID_PHOSPHAT_1, 1 hit
PS00778 HIS_ACID_PHOSPHAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10944-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLLLVLLIG ASGINAVVYK EVPIQANTDT LEYVHTVWRH GDRTPAELLF
60 70 80 90 100
PDDITKWPEG LGELTEQGAA QQYRLGQWLK RRYGSWLGEK FNRNAIYIRS
110 120 130 140 150
SDYNRTLMSA QANMAGLFPP KYPIAGGLMW QPIPVHTISK PTDKELYEEA
160 170 180 190 200
SCPTAEIEMN AQWKSTKANG IRKKFARELS FFSQKLNLPN MELKATWRIF
210 220 230 240 250
DNLFCEKQNN ITWPSWMNSS IFERVDQLYN EVSQLEFHTD TLRRLRGGTL
260 270 280 290 300
LEEIFHRFSD KASGSLGKEA KFYAYSAHDS TIAALLATLG VFYDIYPKYA
310 320 330 340 350
TCLLIEMHKL ANETRLIRVF HKNETDIDRL IEYSIPGCDD PCTLQKLGDD
360 370 380 390 400
LKKYFPEDWE AECGLKTSFQ FIYLVIISIL VISTVCSCTM LFVEKQKRKI
410 420
LRFPVDGLRD DTAPMLGGDD SD
Length:422
Mass (Da):48,409
Last modified:May 30, 2003 - v3
Checksum:i3E29FACB4FAE0CAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080185 Genomic DNA Translation: CCD61822.1
RefSeqiNP_498604.2, NM_066203.7
UniGeneiCel.10942

Genome annotation databases

EnsemblMetazoaiB0361.7.1; B0361.7.1; WBGene00015161
B0361.7.2; B0361.7.2; WBGene00015161
GeneIDi176030
KEGGicel:CELE_B0361.7
UCSCiB0361.7 c. elegans

Similar proteinsi

Entry informationi

Entry nameiPHO5_CAEEL
AccessioniPrimary (citable) accession number: Q10944
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2003
Last modified: May 23, 2018
This is version 111 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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