Reviewed, UniProtKB/Swiss-Prot Q10944 (PPAY_CAEEL)

Names and origin

Protein names

Recommended name:
    Putative acid phosphatase B0361.7
    EC=3.1.3.2

Gene names

ORF Names:

B0361.7

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Domain	Signal
Molecular function	Hydrolase
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 13	13	Potential
	Chain	14 – 422	409	Putative acid phosphatase B0361.7		PRO_0000023968
Sites
	Active site	40	1	Nucleophile By similarity
	Active site	279	1	Proton donor By similarity
Amino acid modifications
	Glycosylation	104	1	N-linked (GlcNAc...) Potential
	Glycosylation	210	1	N-linked (GlcNAc...) Potential
	Glycosylation	218	1	N-linked (GlcNAc...) Potential
	Glycosylation	312	1	N-linked (GlcNAc...) Potential
	Glycosylation	323	1	N-linked (GlcNAc...) Ref.2
	Disulfide bond	152 ↔ 363		By similarity
	Disulfide bond	205 ↔ 302		By similarity
	Disulfide bond	338 ↔ 342		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q10944-1 [UniParc]. Last modified May 30, 2003. Version 3. Checksum: 3E29FACB4FAE0CAC	FASTA	422	48,409
	10 20 30 40 50 60 MLLLLVLLIG ASGINAVVYK EVPIQANTDT LEYVHTVWRH GDRTPAELLF PDDITKWPEG 70 80 90 100 110 120 LGELTEQGAA QQYRLGQWLK RRYGSWLGEK FNRNAIYIRS SDYNRTLMSA QANMAGLFPP 130 140 150 160 170 180 KYPIAGGLMW QPIPVHTISK PTDKELYEEA SCPTAEIEMN AQWKSTKANG IRKKFARELS 190 200 210 220 230 240 FFSQKLNLPN MELKATWRIF DNLFCEKQNN ITWPSWMNSS IFERVDQLYN EVSQLEFHTD 250 260 270 280 290 300 TLRRLRGGTL LEEIFHRFSD KASGSLGKEA KFYAYSAHDS TIAALLATLG VFYDIYPKYA 310 320 330 340 350 360 TCLLIEMHKL ANETRLIRVF HKNETDIDRL IEYSIPGCDD PCTLQKLGDD LKKYFPEDWE 370 380 390 400 410 420 AECGLKTSFQ FIYLVIISIL VISTVCSCTM LFVEKQKRKI LRFPVDGLRD DTAPMLGGDD SD

References

[1]

"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

[2]

"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins." Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T. Mol. Cell. Proteomics 6:2100-2109(2007) [PubMed: 17761667] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-323, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00031 Genomic DNA. Translation: AAK18870.2.
RefSeq	NP_498604.2.
UniGene	Cel.10942
3D structure databases
HSSP	HSSP built from PDB template 1ND5 based on UniProtKB P15309.
ModBase	Search...
Genome annotation databases
Ensembl	B0361.7. Caenorhabditis elegans. [Contig view]
GeneID	176030.
KEGG	cel:B0361.7.
NMPDR	fig|6239.3.peg.10494.
Organism-specific databases
WormBase	WBGene00015161. B0361.7.
WormPep	B0361.7. CE32100. [WorfDB]
Phylogenomic databases
OMA	Q10944. LMSAQAN.
Enzyme and pathway databases
BRENDA	3.1.3.2. 672.
Gene expression databases
ArrayExpress	Q10944.
Family and domain databases
InterPro	IPR000560. Histidine_acid_Pase. [Graphical view]
Pfam	PF00328. Acid_phosphat_A. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	890816.

Entry information

Entry name

PPAY_CAEEL

Accession

Primary (citable) accession number: Q10944

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 30, 2003
Last modified:	June 16, 2009
This is version 56 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project