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Q10941

- UGT46_CAEEL

UniProt

Q10941 - UGT46_CAEEL

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Protein
Putative UDP-glucuronosyltransferase ugt-46
Gene
ugt-46, ugt14, B0310.5
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

  1. glucuronosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-46 (EC:2.4.1.17)
Short name:
UDPGT 46
Gene namesi
Name:ugt-46
Synonyms:ugt14
ORF Names:B0310.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome X

Organism-specific databases

WormBaseiB0310.5; CE03878; WBGene00015141; ugt-46.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei493 – 51321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed prediction
Add
BLAST
Chaini18 – 531514Putative UDP-glucuronosyltransferase ugt-46
PRO_0000036053Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi304 – 3041N-linked (GlcNAc...)1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ10941.
PRIDEiQ10941.

Interactioni

Protein-protein interaction databases

BioGridi45357. 1 interaction.
DIPiDIP-26251N.
IntActiQ10941. 1 interaction.
MINTiMINT-1115290.
STRINGi6239.B0310.5.

Structurei

3D structure databases

ProteinModelPortaliQ10941.
SMRiQ10941. Positions 205-475.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1819.
GeneTreeiENSGT00740000115714.
HOGENOMiHOG000018977.
InParanoidiQ10941.
KOiK00699.
OMAiFSETVME.
OrthoDBiEOG70ZZN0.
PhylomeDBiQ10941.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10941-1 [UniParc]FASTAAdd to Basket

« Hide

MRLIFVLLAT FVNAAFSYKI LVFSPATSKS HLISNGRLAD ELARAGHDVT    50
VLELDFLGIS QTTNSVKVAK KRIIDGFQES TNFKNVLHGF SETVMEEPSF 100
TDEIKGWWAY QNVYNDLCAE FLKMDDIFNE LKNAKFDGFF AEQINLCGFG 150
YAHALEIPRH FLISSCPFAA PVYDFTGLPM PTSTVAFAAD LSISPTYTER 200
ARNLFVAVLT KLEFTLLNNR LQAHFQHKFG EHFPSLYSVT SDVDVIFVAT 250
DEIIDISTTT LQNIVHVGGL GVDDDVAEMD NVFASEMSKG KEGVIYFSLG 300
TIANTTKIDS KVMRTVLDIV KKFPDYHFVI RADKYDLSTR EYAKSVSNAF 350
VSDWLPQPAI LHHPRLKLFI THSGYNSIVE AARAGVPLIN IPFMFDQNLN 400
SRAVEKKGWG IRRHKKQLLT EPEEIEKAIS EIIHNKKYSL KAQRIRDLIK 450
SKPLSSSQLL IKTTEWAIKN HGLDEIKFES RGQTTWTYYN LDVIIPVFWL 500
SISLVIPTIF GWYKFSCFGH VEEKKGKSKR D 531
Length:531
Mass (Da):60,204
Last modified:November 1, 1997 - v1
Checksum:i1C498A4385E272C4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080169 Genomic DNA. Translation: CCD61751.1.
PIRiT15329.
RefSeqiNP_508112.1. NM_075711.5.
UniGeneiCel.11527.

Genome annotation databases

EnsemblMetazoaiB0310.5; B0310.5; WBGene00015141.
GeneIDi180404.
KEGGicel:CELE_B0310.5.
UCSCiB0310.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080169 Genomic DNA. Translation: CCD61751.1 .
PIRi T15329.
RefSeqi NP_508112.1. NM_075711.5.
UniGenei Cel.11527.

3D structure databases

ProteinModelPortali Q10941.
SMRi Q10941. Positions 205-475.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 45357. 1 interaction.
DIPi DIP-26251N.
IntActi Q10941. 1 interaction.
MINTi MINT-1115290.
STRINGi 6239.B0310.5.

Protein family/group databases

CAZyi GT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbi Q10941.
PRIDEi Q10941.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai B0310.5 ; B0310.5 ; WBGene00015141 .
GeneIDi 180404.
KEGGi cel:CELE_B0310.5.
UCSCi B0310.5. c. elegans.

Organism-specific databases

CTDi 180404.
WormBasei B0310.5 ; CE03878 ; WBGene00015141 ; ugt-46.

Phylogenomic databases

eggNOGi COG1819.
GeneTreei ENSGT00740000115714.
HOGENOMi HOG000018977.
InParanoidi Q10941.
KOi K00699.
OMAi FSETVME.
OrthoDBi EOG70ZZN0.
PhylomeDBi Q10941.

Miscellaneous databases

NextBioi 909208.

Family and domain databases

InterProi IPR002213. UDP_glucos_trans.
[Graphical view ]
PANTHERi PTHR11926. PTHR11926. 1 hit.
Pfami PF00201. UDPGT. 1 hit.
[Graphical view ]
PROSITEi PS00375. UDPGT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Identification of the hydrophobic glycoproteins of Caenorhabditis elegans."
    Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J.
    Glycobiology 15:952-964(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-304, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiUGT46_CAEEL
AccessioniPrimary (citable) accession number: Q10941
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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