Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q10941

- UGT46_CAEEL

UniProt

Q10941 - UGT46_CAEEL

Protein

Putative UDP-glucuronosyltransferase ugt-46

Gene

ugt-46

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

    GO - Molecular functioni

    1. glucuronosyltransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT1. Glycosyltransferase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative UDP-glucuronosyltransferase ugt-46 (EC:2.4.1.17)
    Short name:
    UDPGT 46
    Gene namesi
    Name:ugt-46
    Synonyms:ugt14
    ORF Names:B0310.5
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome X

    Organism-specific databases

    WormBaseiB0310.5; CE03878; WBGene00015141; ugt-46.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1717Sequence AnalysisAdd
    BLAST
    Chaini18 – 531514Putative UDP-glucuronosyltransferase ugt-46PRO_0000036053Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi304 – 3041N-linked (GlcNAc...)1 Publication

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ10941.
    PRIDEiQ10941.

    Interactioni

    Protein-protein interaction databases

    BioGridi45357. 1 interaction.
    DIPiDIP-26251N.
    IntActiQ10941. 1 interaction.
    MINTiMINT-1115290.
    STRINGi6239.B0310.5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ10941.
    SMRiQ10941. Positions 205-475.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei493 – 51321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UDP-glycosyltransferase family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1819.
    GeneTreeiENSGT00740000115714.
    HOGENOMiHOG000018977.
    InParanoidiQ10941.
    KOiK00699.
    OMAiFSETVME.
    OrthoDBiEOG70ZZN0.
    PhylomeDBiQ10941.

    Family and domain databases

    InterProiIPR002213. UDP_glucos_trans.
    [Graphical view]
    PANTHERiPTHR11926. PTHR11926. 1 hit.
    PfamiPF00201. UDPGT. 1 hit.
    [Graphical view]
    PROSITEiPS00375. UDPGT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q10941-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLIFVLLAT FVNAAFSYKI LVFSPATSKS HLISNGRLAD ELARAGHDVT    50
    VLELDFLGIS QTTNSVKVAK KRIIDGFQES TNFKNVLHGF SETVMEEPSF 100
    TDEIKGWWAY QNVYNDLCAE FLKMDDIFNE LKNAKFDGFF AEQINLCGFG 150
    YAHALEIPRH FLISSCPFAA PVYDFTGLPM PTSTVAFAAD LSISPTYTER 200
    ARNLFVAVLT KLEFTLLNNR LQAHFQHKFG EHFPSLYSVT SDVDVIFVAT 250
    DEIIDISTTT LQNIVHVGGL GVDDDVAEMD NVFASEMSKG KEGVIYFSLG 300
    TIANTTKIDS KVMRTVLDIV KKFPDYHFVI RADKYDLSTR EYAKSVSNAF 350
    VSDWLPQPAI LHHPRLKLFI THSGYNSIVE AARAGVPLIN IPFMFDQNLN 400
    SRAVEKKGWG IRRHKKQLLT EPEEIEKAIS EIIHNKKYSL KAQRIRDLIK 450
    SKPLSSSQLL IKTTEWAIKN HGLDEIKFES RGQTTWTYYN LDVIIPVFWL 500
    SISLVIPTIF GWYKFSCFGH VEEKKGKSKR D 531
    Length:531
    Mass (Da):60,204
    Last modified:November 1, 1997 - v1
    Checksum:i1C498A4385E272C4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080169 Genomic DNA. Translation: CCD61751.1.
    PIRiT15329.
    RefSeqiNP_508112.1. NM_075711.5.
    UniGeneiCel.11527.

    Genome annotation databases

    EnsemblMetazoaiB0310.5; B0310.5; WBGene00015141.
    GeneIDi180404.
    KEGGicel:CELE_B0310.5.
    UCSCiB0310.5. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FO080169 Genomic DNA. Translation: CCD61751.1 .
    PIRi T15329.
    RefSeqi NP_508112.1. NM_075711.5.
    UniGenei Cel.11527.

    3D structure databases

    ProteinModelPortali Q10941.
    SMRi Q10941. Positions 205-475.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 45357. 1 interaction.
    DIPi DIP-26251N.
    IntActi Q10941. 1 interaction.
    MINTi MINT-1115290.
    STRINGi 6239.B0310.5.

    Protein family/group databases

    CAZyi GT1. Glycosyltransferase Family 1.

    Proteomic databases

    PaxDbi Q10941.
    PRIDEi Q10941.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai B0310.5 ; B0310.5 ; WBGene00015141 .
    GeneIDi 180404.
    KEGGi cel:CELE_B0310.5.
    UCSCi B0310.5. c. elegans.

    Organism-specific databases

    CTDi 180404.
    WormBasei B0310.5 ; CE03878 ; WBGene00015141 ; ugt-46.

    Phylogenomic databases

    eggNOGi COG1819.
    GeneTreei ENSGT00740000115714.
    HOGENOMi HOG000018977.
    InParanoidi Q10941.
    KOi K00699.
    OMAi FSETVME.
    OrthoDBi EOG70ZZN0.
    PhylomeDBi Q10941.

    Miscellaneous databases

    NextBioi 909208.

    Family and domain databases

    InterProi IPR002213. UDP_glucos_trans.
    [Graphical view ]
    PANTHERi PTHR11926. PTHR11926. 1 hit.
    Pfami PF00201. UDPGT. 1 hit.
    [Graphical view ]
    PROSITEi PS00375. UDPGT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.
    2. "Identification of the hydrophobic glycoproteins of Caenorhabditis elegans."
      Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J.
      Glycobiology 15:952-964(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-304, IDENTIFICATION BY MASS SPECTROMETRY.

    Entry informationi

    Entry nameiUGT46_CAEEL
    AccessioniPrimary (citable) accession number: Q10941
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3