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Protein

Probable 26S proteasome non-ATPase regulatory subunit 9

Gene

psmd-9

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).By similarity

GO - Biological processi

Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

ReactomeiR-CEL-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 26S proteasome non-ATPase regulatory subunit 9
Gene namesi
Name:psmd-9
ORF Names:C44B7.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiC44B7.1; CE25810; WBGene00016623; psmd-9.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001738551 – 197Probable 26S proteasome non-ATPase regulatory subunit 9Add BLAST197

Proteomic databases

EPDiQ10920.
PaxDbiQ10920.
PeptideAtlasiQ10920.
PRIDEiQ10920.

Expressioni

Gene expression databases

BgeeiWBGene00016623.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
rpt-5O763713EBI-317193,EBI-317201

Protein-protein interaction databases

IntActiQ10920. 6 interactors.
MINTiMINT-211419.
STRINGi6239.C44B7.1.1.

Structurei

3D structure databases

ProteinModelPortaliQ10920.
SMRiQ10920.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 166PDZAdd BLAST92

Sequence similaritiesi

Belongs to the proteasome subunit p27 family.Curated

Phylogenomic databases

eggNOGiKOG3129. Eukaryota.
COG0265. LUCA.
GeneTreeiENSGT00390000004147.
HOGENOMiHOG000216665.
InParanoidiQ10920.
KOiK06693.
OMAiLGCNIVP.
OrthoDBiEOG091G0N53.
PhylomeDBiQ10920.

Family and domain databases

InterProiView protein in InterPro
IPR001478. PDZ.
SUPFAMiSSF50156. SSF50156. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10920-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDHHSKAKEL LQQRDELDGK IKELMLVLET NNSTMDSPLL DAEGYPLNTI
60 70 80 90 100
DVYAVRHARH DLICLRNDRA ALTEKIVVEM ENENKEVSGQ TATSEEKPVH
110 120 130 140 150
RTSNEPFVKI SSVVELSPAD IGGFRKDDLI IQYGNLHHGN FNDMQEVAQI
160 170 180 190
TKQSEDKIIR VTVIRENRPV RLEICPKKWS GPGLLGCNIV PISGANV
Length:197
Mass (Da):22,133
Last modified:July 19, 2003 - v2
Checksum:iE6693CE5141FE0E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080139 Genomic DNA. Translation: CCD61554.1.
PIRiT15289.
RefSeqiNP_001293499.1. NM_001306570.1.

Genome annotation databases

EnsemblMetazoaiC44B7.1; C44B7.1; WBGene00016623.
GeneIDi24104302.
KEGGicel:CELE_C44B7.1.
UCSCiC44B7.1.2. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPSMD9_CAEEL
AccessioniPrimary (citable) accession number: Q10920
Secondary accession number(s): G8JXY6, Q95QR4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 19, 2003
Last modified: June 7, 2017
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families