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Q10880 (Y051_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized protein Rv0083/MT0090
Gene names
Ordered Locus Names:Rv0083, MT0090
ORF Names:MTCY251.01, MTV030.27
OrganismMycobacterium tuberculosis
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length640 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the complex I subunit 4 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processATP synthesis coupled electron transport

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 640640Uncharacterized protein Rv0083/MT0090
PRO_0000118049

Regions

Transmembrane8 – 2821Helical; Potential
Transmembrane52 – 7221Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane136 – 15621Helical; Potential
Transmembrane179 – 19921Helical; Potential
Transmembrane208 – 22821Helical; Potential
Transmembrane241 – 26121Helical; Potential
Transmembrane277 – 29721Helical; Potential
Transmembrane298 – 31821Helical; Potential
Transmembrane352 – 37221Helical; Potential
Transmembrane391 – 41121Helical; Potential
Transmembrane446 – 46621Helical; Potential
Transmembrane497 – 51721Helical; Potential
Transmembrane619 – 63921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q10880 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: 6254C289DBD108A8

FASTA64065,628
        10         20         30         40         50         60 
MTAAPTAGGV VTSGVGVAGV GVGLLGMFGP VRVVHVGWLL PLSGVHIELD RLGGFFMALT 

        70         80         90        100        110        120 
GAVAAPVGCY LIGYVRREHL GRVPMAVVPL FVAAMLLVPA AGSVTTFLLA WELMAIASLI 

       130        140        150        160        170        180 
LVLSEHARPQ VRSAGLWYAV MTQLGFIAIL VGLVVLAAAG GSDRFAGLGA VCDGVRAAVF 

       190        200        210        220        230        240 
MLTLVGFGSK AGLVPLHAWL PRAHPEAPSP VSALMSAAMV NLGIYGIVRF DLQLLGPGPR 

       250        260        270        280        290        300 
WWGLALLAVG GTSALYGVLQ ASVAADLKRL LAYSTTENMG LITLALGAAT LFADTGAYGP 

       310        320        330        340        350        360 
ASIAAAAAML HMIAHAAFKS LAFMAAGSVL AATGLRDLDL LGGLARRMPA TTVFFGVAAL 

       370        380        390        400        410        420 
GACGLPLGAG FVSEWLLVQS LIHAAPGHDP IVALTTPLAV GVVALATGLS VAAMTKAFGI 

       430        440        450        460        470        480 
GFLARPRSTQ AEAAREAPAS MRAGMAIAAG ACLVLAVAPL LVAPMVRRAA ATLPAAQAVK 

       490        500        510        520        530        540 
FTGLGAVVRL PAMSGSIAPG VIAAAVLAAA LAVAVLARWR FRRRPAPARL PLWACGAADL 

       550        560        570        580        590        600 
TVRMQYTATS FAEPLQRVFG DVLRPDTDIE VTHTAESRYM AERITYRTAV ADAIEQRLYT 

       610        620        630        640 
PVVGAVAAMA ELLRRAHTGS VHRYLAYGAL GVLIVLVVAR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX842572 Genomic DNA. Translation: CAA16264.1.
AE000516 Genomic DNA. Translation: AAK44315.1.
PIRD70850.
RefSeqNP_214597.1. NC_000962.2.
NP_334501.1. NC_002755.2.

3D structure databases

ProteinModelPortalQ10880.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000002481; EBMYCP00000002481; EBMYCG00000002479.
EBMYCT00000069409; EBMYCP00000067468; EBMYCG00000069404.
GeneID886965.
922874.
GenomeReviewsGene locus MT0090 in contig AE000516_GR.
Gene locus Rv0083 in contig AL123456_GR.
KEGGmtc:MT0090.
mtu:Rv0083.
PATRIC18121923. VBIMycTub22151_0096.
TIGRMT0090.

Organism-specific databases

TubercuListRv0083.

Phylogenomic databases

GeneTreeEBGT00050000015714.
HOGENOMHBG643593.
OMAIMAISAY.
PhylomeDBQ10880.
ProtClustDBCLSK790248.

Family and domain databases

InterProIPR001750. NADH_UbQ/plastoQ_OxRdtase.
IPR003918. NADH_UbQ_OxRdtase.
[Graphical view]
KOK00540.
PfamPF00361. Oxidored_q1. 1 hit.
[Graphical view]
PRINTSPR01437. NUOXDRDTASE4.
ProtoNetSearch...

Entry information

Entry nameY051_MYCTU
AccessionPrimary (citable) accession number: Q10880
Secondary accession number(s): O53628
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 15, 1998
Last modified: January 25, 2012
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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