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Protein
Submitted name:

Preprocathepsin cathepsin L

Gene
N/A
Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiI29.003.

Names & Taxonomyi

Protein namesi
Submitted name:
Preprocathepsin cathepsin LImported
OrganismiSchistosoma japonicum (Blood fluke)Imported
Taxonomic identifieri6182 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16UniRule annotationAdd BLAST16
ChainiPRO_500540002317 – 331UniRule annotationAdd BLAST315

Structurei

3D structure databases

ProteinModelPortaliQ10834.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 87Inhibitor_I29InterPro annotationAdd BLAST61
Domaini116 – 329Pept_C1InterPro annotationAdd BLAST214

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiView protein in Pfam
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
PRINTSiPR00705. PAPAIN.
SMARTiView protein in SMART
SM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
PROSITEiView protein in PROSITE
PS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10834-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVFLLFSII TAITVAQHYD KQYDEIWRQW KLKYNKTYTS NDDEMRRKMI
60 70 80 90 100
FMRRIGKIQE HNLRHDLGLE GYTMGLNQFC DMEWEEVNRI MFPKVFGNSP
110 120 130 140 150
LWNDDGNELE LTNKPVPSTW DWRDHGAVTA VKHQGLCGSC WAFSATGAIE
160 170 180 190 200
GQLRRKHKKL VKLSEQQLVD CRYNYGNDGC EGGTMDLAFN YLEKHYIESE
210 220 230 240 250
NDYKYLGHDA NCHYRKSKGV VKVKKFGDLP ARDEKTLEKA VYQYGPISVG
260 270 280 290 300
IVALDSLILY KSGIYESKDC KYADINHGVL AVGYGRENGK DYWLIKNSWG
310 320 330
DLWGMNGYFK LRRNKPHMCG ISSNSSFPFK L
Length:331
Mass (Da):38,460
Last modified:November 1, 1996 - v1
Checksum:i5FFCC9561FE9C9DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38476 mRNA. Translation: AAA87849.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ10834_SCHJA
AccessioniPrimary (citable) accession number: Q10834
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)