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Protein
Submitted name:

Ketoacyl reductase

Gene

Rv1544

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • active evasion of host immune response Source: MTBBASE
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ketoacyl reductaseImported
Submitted name:
Possible ketoacyl reductaseImported
Gene namesi
Ordered Locus Names:Rv1544Imported
ORF Names:LH57_08455Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1544.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1544.

Structurei

3D structure databases

SMRiQ10782. Positions 11-220.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IXY. Bacteria.
COG0300. LUCA.
KOiK07124.
OMAiPRYALIT.
PhylomeDBiQ10782.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q10782-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLPKPNNQT TVVITGASSG IGVELARGLA GRGFPLMLVA RRRERLDELA
60 70 80 90 100
DQLRQEHCVG VEVLPLDLAD TQARAQLADR LRSDAIAGLC NSAGFGTSGR
110 120 130 140 150
FWELPFARES EEVVLNALAL MELTHAALPG MVKRGAGAVL NIASIAGFQP
160 170 180 190 200
IPYMAVYSAT KAFVLTFSEA VQEELHGTGV SVTALCPGPV PTEWAEIASA
210 220 230 240 250
ERFSIPLAQV SPHDVAEAAI AGMLSGKRTV VPGIVPKFVS TSGRFAPRSL
260
LLPAIRIGNR LRGGPSR
Length:267
Mass (Da):28,200
Last modified:November 1, 1996 - v1
Checksum:iCDBE2B01180E7BCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14298.1.
AL123456 Genomic DNA. Translation: CCP44308.1.
RefSeqiNP_216060.1. NC_000962.3.
WP_003407737.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14298; AIR14298; LH57_08455.
CCP44308; CCP44308; Rv1544.
GeneIDi886417.
KEGGimtu:Rv1544.
mtv:RVBD_1544.
PATRICi18125275. VBIMycTub22151_1752.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14298.1.
AL123456 Genomic DNA. Translation: CCP44308.1.
RefSeqiNP_216060.1. NC_000962.3.
WP_003407737.1. NZ_KK339370.1.

3D structure databases

SMRiQ10782. Positions 11-220.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1544.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14298; AIR14298; LH57_08455.
CCP44308; CCP44308; Rv1544.
GeneIDi886417.
KEGGimtu:Rv1544.
mtv:RVBD_1544.
PATRICi18125275. VBIMycTub22151_1752.

Organism-specific databases

TubercuListiRv1544.

Phylogenomic databases

eggNOGiENOG4108IXY. Bacteria.
COG0300. LUCA.
KOiK07124.
OMAiPRYALIT.
PhylomeDBiQ10782.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ10782_MYCTU
AccessioniPrimary (citable) accession number: Q10782
Secondary accession number(s): F2GE58, I6X1K2, Q7D8B1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.