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Protein

Cysteine proteinase 1

Gene

CCP1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the degradation of the storage protein zein. May play a role in proteolysis during emergencies.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei161By similarity1
Active sitei303By similarity1
Active sitei330By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease

Protein family/group databases

MEROPSiC01.022

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine proteinase 1 (EC:3.4.22.-)
Gene namesi
Name:CCP1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi25431

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
PropeptideiPRO_000002642819 – 136Activation peptideSequence analysisAdd BLAST118
ChainiPRO_0000026429137 – 371Cysteine proteinase 1Add BLAST235

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi158 ↔ 208By similarity
Disulfide bondi196 ↔ 241By similarity
Glycosylationi254N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi297 ↔ 345By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

PaxDbiQ10716
PRIDEiQ10716

Expressioni

Tissue specificityi

Expressed during the late stages of seed ripening, in mature seeds and during germination.

Gene expression databases

ExpressionAtlasiQ10716 differential

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G098298_P01

Structurei

3D structure databases

ProteinModelPortaliQ10716
SMRiQ10716
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1542 Eukaryota
COG4870 LUCA
HOGENOMiHOG000230774
KOiK01373

Family and domain databases

InterProiView protein in InterPro
IPR025661 Pept_asp_AS
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR013201 Prot_inhib_I29
PANTHERiPTHR12411 PTHR12411, 1 hit
PfamiView protein in Pfam
PF08246 Inhibitor_I29, 1 hit
PF00112 Peptidase_C1, 1 hit
PRINTSiPR00705 PAPAIN
SMARTiView protein in SMART
SM00848 Inhibitor_I29, 1 hit
SM00645 Pept_C1, 1 hit
PROSITEiView protein in PROSITE
PS00640 THIOL_PROTEASE_ASN, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10716-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHRVLLLLS LASAAAVAAA VDAEDPLIRQ VVPGGDDNDL ELNAESHFLS
60 70 80 90 100
FVQRFGKSYK DADEHAYRLS VFKDNLRRAR RHQLLDPSAE HGVTKFSDLT
110 120 130 140 150
PAEFRRTYLG LRKSRRALLR ELGESAHEAP VLPTDGLPDD FDWRDHGAVG
160 170 180 190 200
PVKNQGSCGS CWSFSASGAL EGAHYLATGK LEVLSEQQFV DCDHECDSSE
210 220 230 240 250
PDSCDSGCNG GLMTTAFSYL QKAGGLESEK DYPYTGSDGK CKFDKSKIVA
260 270 280 290 300
SVQNFSVVSV DEAQISANLI KHGPLAIGIN AAYMQTYIGG VSCPYICGRH
310 320 330 340 350
LDHGVLLVGY GASGFAPIRL KDKPYWIIKN SWGENWGENG YYKICRGSNV
360 370
RNKCGVDSMV STVSAVHASK E
Length:371
Mass (Da):40,347
Last modified:October 1, 1996 - v1
Checksum:i59042B03266E6058
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti269L → R in CAA57675 (PubMed:7632917).Curated1
Sequence conflicti318I → M in CAA57675 (PubMed:7632917).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45402 mRNA Translation: BAA08244.1
X82185 mRNA Translation: CAA57675.1
PIRiS59597
S60456
RefSeqiNP_001105685.1, NM_001112215.1
UniGeneiZm.5565

Genome annotation databases

GeneIDi542701
KEGGizma:542701

Similar proteinsi

Entry informationi

Entry nameiCYSP1_MAIZE
AccessioniPrimary (citable) accession number: Q10716
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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