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Reviewed, UniProtKB/Swiss-Prot Q10462 (CAH5_CAEEL)

Last modified June 16, 2009. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Putative carbonic anhydrase 5
    EC=4.2.1.1
Alternative name(s):
    Carbonate dehydratase 5
Gene names
Name: cah-5
ORF Names: R173.1
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

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Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Reversible hydration of carbon dioxide.

Catalytic activity

H2CO3 = CO2 + H2O.

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the alpha-carbonic anhydrase family.

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Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandMetal-binding
Zinc
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processone-carbon compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncarbonate dehydratase activity

Inferred from electronic annotation. Source: EC

zinc ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 310290Putative carbonic anhydrase 5
PRO_0000004256

Sites

Metal binding1171Zinc; catalytic
Metal binding1191Zinc; catalytic
Metal binding1421Zinc; catalytic

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Sequences

Sequence LengthMass (Da)Tools
Q10462-1 [UniParc].

Last modified July 19, 2004. Version 3.
Checksum: 696A8ED5355DB186

FASTA31034,862
        10         20         30         40         50         60 
MPSHLLVLSL LVALLVVVSC GPGSDHGWGY DENNGPDTWQ GKCQNHLKQS PIDIRAPDVD 

        70         80         90        100        110        120 
YALLHRMHFL NYDMDGKIEL SNTGRTLFAG GFESWQHKQP MIQGGGLKHR YKLAQFHLHW 

       130        140        150        160        170        180 
GQNDAVGSEH AMGSLHYPAE LHLVHVREGL TLKEALSRPD GLAVVGVFLA KTNDPVANKF 

       190        200        210        220        230        240 
SPISERLHDL RHSGNKTELK NFRTKYVLPL DTEAFYRYEG SLTTPDCSEA VIWTVLAEPM 

       250        260        270        280        290        300 
AISSHQLHLL RQLHNKELVK SDKNYRPLQP LNGRRIQYRP SKLDRAMICS SFATTSVIIT 

       310 
YVAILSAMLI

« Hide

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References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

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Cross-references

Sequence databases

U39743 Genomic DNA. Translation: AAA80437.6.
PIRT16772.
RefSeqNP_509186.3.
UniGeneCel.20861

3D structure databases

HSSPHSSP built from PDB template 1CIM based on UniProtKB P00918.
ModBaseSearch...

Genome annotation databases

EnsemblR173.1. Caenorhabditis elegans. [Contig view]
GeneID180972.
KEGGcel:R173.1.
NMPDRfig|6239.3.peg.23672.

Organism-specific databases

WormBaseWBGene00000283. cah-5.
WormPepR173.1. CE36560. [WorfDB]

Phylogenomic databases

OMAQ10462. DSITISE.

Enzyme and pathway databases

BRENDA4.2.1.1. 672.

Gene expression databases

ArrayExpressQ10462.

Family and domain databases

InterProIPR001148. Carbonic_anhydrase_a-class_cat.
IPR018338. Carbonic_anhydrase_a-class_CS.
[Graphical view]
Gene3DG3DSA:3.10.200.10. Euk_COanhd. 1 hit.
PANTHERPTHR18952. Euk_COanhd. 1 hit.
PfamPF00194. Carb_anhydrase. 1 hit.
[Graphical view]
ProDomPD000865. Euk_COanhd. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00162. ALPHA_CA_1. 1 hit.
PS51144. ALPHA_CA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio911796.

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Entry information

Entry nameCAH5_CAEEL
AccessionPrimary (citable) accession number: Q10462
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 19, 2004
Last modified: June 16, 2009
This is version 58 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

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Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents