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Protein

Coiled-coil quantitatively-enriched protein 1

Gene

ccq1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic centrosome component pcp1. Essential for the formation of normal telomere clusters during meiotic prophase. Required for telomere length regulation and chromosome segregation. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).3 Publications

GO - Biological processi

  • cellular protein localization Source: PomBase
  • chromatin silencing at telomere Source: PomBase
  • meiotic chromosome segregation Source: PomBase
  • meiotic telomere clustering Source: PomBase
  • negative regulation of DNA recombination at telomere Source: PomBase
  • negative regulation of telomere maintenance via telomerase Source: PomBase
  • positive regulation of telomerase activity Source: PomBase
  • positive regulation of telomere maintenance Source: PomBase
  • positive regulation of telomere maintenance via telomerase Source: PomBase
  • telomere capping Source: PomBase
  • telomere maintenance Source: PomBase
  • telomere-telomerase complex assembly Source: PomBase

Keywordsi

Biological processChromosome partition

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil quantitatively-enriched protein 1
Alternative name(s):
Structural maintenance of chromosomes protein ccq1
Short name:
SMC protein ccq1
Gene namesi
Name:ccq1
ORF Names:SPCC188.07
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC188.07
PomBaseiSPCC188.07 ccq1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus, Telomere

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001168821 – 735Coiled-coil quantitatively-enriched protein 1Add BLAST735

Proteomic databases

MaxQBiQ10432
PaxDbiQ10432
PRIDEiQ10432

PTM databases

iPTMnetiQ10432

Interactioni

Subunit structurei

Interacts (during meiosis) with pcp1. Interacts with clr3, pot1, taz1 and tpz1.3 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi275918, 72 interactors
DIPiDIP-59444N
IntActiQ10432, 3 interactors
STRINGi4896.SPCC188.07.1

Structurei

3D structure databases

ProteinModelPortaliQ10432
SMRiQ10432
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili514 – 719Sequence analysisAdd BLAST206

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiQ10432
OrthoDBiEOG092C1FW5

Sequencei

Sequence statusi: Complete.

Q10432-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEINDFTNS IIINESDTKY EVYSEVNSSN RWIAKEDCPS PLEDVWLLKL
60 70 80 90 100
AGHKRKLEEP LSCMRNEEPA SKQREIEKFL RTDLDHSEND FLTQEVDEFP
110 120 130 140 150
STQQLFPIPL QNDTAFDSSE ESITKSSKSS FSVLDIGLPM SALQRKMMHR
160 170 180 190 200
LVQYFAFCID HFCTGPSDSR IQEKIRLFIQ SAHNIAKHPS LYDTEVRNPS
210 220 230 240 250
AAESTNSHVS LDASNFSSYA ENSSKFLFLQ ELFKNLSPSY SKTFFLFISN
260 270 280 290 300
QFLANTLTQW LKSQNIDAEL WAEEDAKTSQ HPAIWICVSK KAPSASHFLQ
310 320 330 340 350
SCPDLSATIF YDIEAYMSVT SSLPSIQSLV LRLIHLGSIE HAIKCFQSSY
360 370 380 390 400
NASFLVNIVG VVATLSSSSE ENSEASNLST LFEKSGNFEE ILGSESHSSI
410 420 430 440 450
TEKTRDIAKN VATWLKNGEN FSSWPLPPLM DLASLSVAEP RDSQPSVSQV
460 470 480 490 500
NDTFVKSSDS TFPSSQSMQS PSKLHSLTSN ATDLLSSSSL KKNFFSQQEA
510 520 530 540 550
DEVELSNNYD LQGAAVQYLQ RRLRMVEDEL HEAINSKNVQ QSRSEELEQQ
560 570 580 590 600
ISKLTDNLQE YRNTVRELKL DLEKSKKKNE DLSKLEVEKV EEIANLKKEL
610 620 630 640 650
THLAKQQEFG FKYVQEFSNE DLQGKLIEAN EKNYKLTQLL KTQKEDADFI
660 670 680 690 700
TNQYQNASTF AAEQSKEVAK LQAECKRLQA INSKVMEEVK VYNDSRVEAL
710 720 730
LAKVSSLEET LKILEQKSLP KFTPHNQSPR IIDSN
Length:735
Mass (Da):83,301
Last modified:October 1, 1996 - v1
Checksum:i14193682700A2634
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAB41227.1
PIRiT41187
RefSeqiNP_588210.1, NM_001023200.2

Genome annotation databases

EnsemblFungiiSPCC188.07.1; SPCC188.07.1:pep; SPCC188.07
GeneIDi2539352
KEGGispo:SPCC188.07

Similar proteinsi

Entry informationi

Entry nameiCCQ1_SCHPO
AccessioniPrimary (citable) accession number: Q10432
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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