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Protein

Putative phospholipid-transporting ATPase C6C3.06c

Gene

SPAC6C3.06c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei408 – 40814-aspartylphosphate intermediateBy similarity
Metal bindingi770 – 7701MagnesiumBy similarity
Metal bindingi774 – 7741MagnesiumBy similarity

GO - Molecular functioni

GO - Biological processi

  • calcium ion transmembrane transport Source: PomBase
  • phospholipid translocation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C6C3.06c (EC:3.6.3.1)
Gene namesi
ORF Names:SPAC6C3.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC6C3.06c.
PomBaseiSPAC6C3.06c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei133 – 15321HelicalSequence analysisAdd
BLAST
Transmembranei274 – 29421HelicalSequence analysisAdd
BLAST
Transmembranei317 – 33721HelicalSequence analysisAdd
BLAST
Transmembranei344 – 36421HelicalSequence analysisAdd
BLAST
Transmembranei768 – 78821HelicalSequence analysisAdd
BLAST
Transmembranei843 – 86321HelicalSequence analysisAdd
BLAST
Transmembranei913 – 93321HelicalSequence analysisAdd
BLAST
Transmembranei939 – 95921HelicalSequence analysisAdd
BLAST
Transmembranei965 – 98521HelicalSequence analysisAdd
BLAST
Transmembranei992 – 101221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • endoplasmic reticulum membrane Source: PomBase
  • Golgi apparatus Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10331033Putative phospholipid-transporting ATPase C6C3.06cPRO_0000046319Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ10309.

PTM databases

SwissPalmiQ10309.

Interactioni

Protein-protein interaction databases

BioGridi279357. 17 interactions.
MINTiMINT-4698618.

Structurei

3D structure databases

ProteinModelPortaliQ10309.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000201571.
InParanoidiQ10309.
KOiK01530.
OMAiIVKWTEA.
OrthoDBiEOG7FR7QR.
PhylomeDBiQ10309.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q10309-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRLNRIQS KMKLWIKDKN LSNPSIPLKV LNKSFRSSRQ SSVSNGHGLY
60 70 80 90 100
SLDRDETESL MSSHEASNAG ISLDSSFRVI QVGQPEPQYG NNAVTNTKYD
110 120 130 140 150
LFTFLPKCLY EQFRYFYNMY FLLVSLSQLI PPLKIGYLST YIAPLIFVLL
160 170 180 190 200
ITLTKEAVDD LKRRRRDSYA NNEIYTVNDS PCAAQNIQAG DVVYIAKDQR
210 220 230 240 250
IPADMILLET TVGNEAFIRT DQLDGETDWK LRIPCSNQHT EGIVHADAPI
260 270 280 290 300
KSVHHFYGTF TLNNQKRPIS VDHTLWANTV LASDGVYGVV VYTGKDTRQS
310 320 330 340 350
MNSSKAKTKV GLLEKEINFY SKILCTFVLV LSIGLTFSHG IKTDWYISVF
360 370 380 390 400
RYLILFSSII PINLRVNLDL AKIVHSKNTE SDPNLPGVVV RSSNIPEELG
410 420 430 440 450
RIEYVLTDKT GTLTQNEMEM KKLHVGTMGF SAESMDVVQA CIQNYSTPIP
460 470 480 490 500
LSEDSKTLVR NLVLALSLCH NVTPSKGHDG VVSYQAASPD EVAIVKWTST
510 520 530 540 550
LGLVLTNRTR DAITLNNNVY KILNIFPFKS ETKRMGIIVQ SPDEKITFYL
560 570 580 590 600
KGADSIMQNF VKPSFWLEEE CGNLAREGLR TLVVAKKDLS AEEYSAFSLA
610 620 630 640 650
HSDASLSFSN SRDKKMEEIV SRYLENDMDL LGLTGVEDKL QKDVKITLEL
660 670 680 690 700
LRNAGIHVWM LTGDKVETAR CIAISSRLVS RGQYIHTINQ LSSREEAHNH
710 720 730 740 750
LLTLRNKPDS CLIIDGESME FCIGYLQNEF IDIVSDLSSV VICRCTPTQK
760 770 780 790 800
ANMTRLIQEK KQASVCCIGD GGNDVGMIQV ANVGIGIVGK EGQQASLAAD
810 820 830 840 850
YSVKEFSHVS RLLLWHGRIS YKQTSKLAMF VIHRGLLISV CQVVYSVISA
860 870 880 890 900
FEPIALFQGL LLVGYSTMYT MLPVFSIVYD RDVSEKLVFL FPELYKEMRE
910 920 930 940 950
QKCFSYKNFI SCVLISVYQG LIIQLFTFYL IGFEEEGKML AVCFSCLIFN
960 970 980 990 1000
ELIMVALQIN TWEQTIVMSE LLTLMMYILS VPFLTNYFEL KFLLGLKFYW
1010 1020 1030
VSALILFISL LPVWCGKALK RKLKPSSYAK LQR
Length:1,033
Mass (Da):116,588
Last modified:October 1, 1996 - v1
Checksum:iD57C467427D0C6D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93618.1.
PIRiT39030.
RefSeqiNP_593720.1. NM_001019151.2.

Genome annotation databases

EnsemblFungiiSPAC6C3.06c.1; SPAC6C3.06c.1:pep; SPAC6C3.06c.
GeneIDi2542915.
KEGGispo:SPAC6C3.06c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93618.1.
PIRiT39030.
RefSeqiNP_593720.1. NM_001019151.2.

3D structure databases

ProteinModelPortaliQ10309.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279357. 17 interactions.
MINTiMINT-4698618.

PTM databases

SwissPalmiQ10309.

Proteomic databases

MaxQBiQ10309.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC6C3.06c.1; SPAC6C3.06c.1:pep; SPAC6C3.06c.
GeneIDi2542915.
KEGGispo:SPAC6C3.06c.

Organism-specific databases

EuPathDBiFungiDB:SPAC6C3.06c.
PomBaseiSPAC6C3.06c.

Phylogenomic databases

HOGENOMiHOG000201571.
InParanoidiQ10309.
KOiK01530.
OMAiIVKWTEA.
OrthoDBiEOG7FR7QR.
PhylomeDBiQ10309.

Miscellaneous databases

NextBioi20803952.
PROiQ10309.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiYD56_SCHPO
AccessioniPrimary (citable) accession number: Q10309
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 11, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.