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Protein
Submitted name:

Glucose transporter 2

Gene

slc2a2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • D-glucose transmembrane transporter activity Source: ZFIN

GO - Biological processi

  • brain development Source: ZFIN
  • glucose import Source: ZFIN
  • glucose transmembrane transport Source: ZFIN
  • hexose transmembrane transport Source: ZFIN
  • liver development Source: ZFIN

Keywordsi

Biological processSugar transportImported, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glucose transporter 2Imported
Gene namesi
Name:slc2a2Imported
Synonyms:glut2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-030131-1213 slc2a2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei72 – 93HelicalSequence analysisAdd BLAST22
Transmembranei105 – 123HelicalSequence analysisAdd BLAST19
Transmembranei129 – 154HelicalSequence analysisAdd BLAST26
Transmembranei166 – 188HelicalSequence analysisAdd BLAST23
Transmembranei194 – 217HelicalSequence analysisAdd BLAST24
Transmembranei282 – 305HelicalSequence analysisAdd BLAST24
Transmembranei317 – 338HelicalSequence analysisAdd BLAST22
Transmembranei345 – 367HelicalSequence analysisAdd BLAST23
Transmembranei373 – 391HelicalSequence analysisAdd BLAST19
Transmembranei412 – 436HelicalSequence analysisAdd BLAST25
Transmembranei442 – 460HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ102R8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 466MFSInterPro annotationAdd BLAST455

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili251 – 271Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
HOVERGENiHBG014816
KOiK07593

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 2 hits
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q102R8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKQLTGTLA LAVFTAALGS LQMGYSLGVI NAPQKVIERH YARSLGVYNE
60 70 80 90 100
DLARSEGGNG TEHEKPTDPS VVMYWSLSVA IFSVGGMLSS FLVSFVGDFR
110 120 130 140 150
GRIKGMLAIN VLAITAGLLM GLAKMGTPHL MVIAGRAIMG LYCGLSSGLV
160 170 180 190 200
PLYIGEISPV KYRGAMGALH QLAIVIGILI SQVIGLDFLL GNDYMWHILL
210 220 230 240 250
GLSGAPAILQ SLLLLVCPES PRYLYIKQGK VEDACKSLKR LKGDYDTSKD
260 270 280 290 300
IAEMKAEKEE AMKEAKMSIL RLLRSSVYRQ QLFVALMMHF SQQFSGINAI
310 320 330 340 350
FYYSTSIFQT AGVGQPVYAT IGVGVVNIIF TLVSVLMVDR AGRRTLTLVG
360 370 380 390 400
LGGMCCCAVA MTVGLAFQGA YSWMSYVSMV AIFMFVSFFE IGPGPIPWFI
410 420 430 440 450
VAEIFSQGPR PAAIALAGFC NWTCNFIVGM VFPYLVSLCG SYVFIVFAVL
460 470 480 490 500
LFGFTLFIYF RVPETKGKTF EEIAAVFHRK HGGVPPSKPQ EEAEMVQLKG

SSEA
Length:504
Mass (Da):54,769
Last modified:August 22, 2006 - v1
Checksum:i496BD3A7645D0054
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ098687 mRNA Translation: AAZ43092.1
RefSeqiNP_001036186.1, NM_001042721.1
UniGeneiDr.77184

Genome annotation databases

GeneIDi322493
KEGGidre:322493

Similar proteinsi

Entry informationi

Entry nameiQ102R8_DANRE
AccessioniPrimary (citable) accession number: Q102R8
Entry historyiIntegrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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