Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Glucose transporter 2

Gene

slc2a2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • D-glucose transmembrane transporter activity Source: ZFIN

GO - Biological processi

  • brain development Source: ZFIN
  • glucose import Source: ZFIN
  • glucose transmembrane transport Source: GOC
  • glucose transport Source: ZFIN
  • hexose transport Source: ZFIN
  • liver development Source: ZFIN
Complete GO annotation...

Keywords - Biological processi

Sugar transportImported, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glucose transporter 2Imported
Gene namesi
Name:slc2a2Imported
Synonyms:glut2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-030131-1213. slc2a2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei72 – 9322HelicalSequence analysisAdd
BLAST
Transmembranei105 – 12319HelicalSequence analysisAdd
BLAST
Transmembranei129 – 15426HelicalSequence analysisAdd
BLAST
Transmembranei166 – 18823HelicalSequence analysisAdd
BLAST
Transmembranei194 – 21724HelicalSequence analysisAdd
BLAST
Transmembranei282 – 30524HelicalSequence analysisAdd
BLAST
Transmembranei317 – 33822HelicalSequence analysisAdd
BLAST
Transmembranei345 – 36723HelicalSequence analysisAdd
BLAST
Transmembranei373 – 39119HelicalSequence analysisAdd
BLAST
Transmembranei412 – 43625HelicalSequence analysisAdd
BLAST
Transmembranei442 – 46019HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ102R8.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073100.

Structurei

3D structure databases

ProteinModelPortaliQ102R8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 466455MFSInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
KOiK07593.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q102R8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKQLTGTLA LAVFTAALGS LQMGYSLGVI NAPQKVIERH YARSLGVYNE
60 70 80 90 100
DLARSEGGNG TEHEKPTDPS VVMYWSLSVA IFSVGGMLSS FLVSFVGDFR
110 120 130 140 150
GRIKGMLAIN VLAITAGLLM GLAKMGTPHL MVIAGRAIMG LYCGLSSGLV
160 170 180 190 200
PLYIGEISPV KYRGAMGALH QLAIVIGILI SQVIGLDFLL GNDYMWHILL
210 220 230 240 250
GLSGAPAILQ SLLLLVCPES PRYLYIKQGK VEDACKSLKR LKGDYDTSKD
260 270 280 290 300
IAEMKAEKEE AMKEAKMSIL RLLRSSVYRQ QLFVALMMHF SQQFSGINAI
310 320 330 340 350
FYYSTSIFQT AGVGQPVYAT IGVGVVNIIF TLVSVLMVDR AGRRTLTLVG
360 370 380 390 400
LGGMCCCAVA MTVGLAFQGA YSWMSYVSMV AIFMFVSFFE IGPGPIPWFI
410 420 430 440 450
VAEIFSQGPR PAAIALAGFC NWTCNFIVGM VFPYLVSLCG SYVFIVFAVL
460 470 480 490 500
LFGFTLFIYF RVPETKGKTF EEIAAVFHRK HGGVPPSKPQ EEAEMVQLKG

SSEA
Length:504
Mass (Da):54,769
Last modified:August 22, 2006 - v1
Checksum:i496BD3A7645D0054
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ098687 mRNA. Translation: AAZ43092.1.
RefSeqiNP_001036186.1. NM_001042721.1.
UniGeneiDr.77184.

Genome annotation databases

GeneIDi322493.
KEGGidre:322493.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ098687 mRNA. Translation: AAZ43092.1.
RefSeqiNP_001036186.1. NM_001042721.1.
UniGeneiDr.77184.

3D structure databases

ProteinModelPortaliQ102R8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073100.

Proteomic databases

PaxDbiQ102R8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi322493.
KEGGidre:322493.

Organism-specific databases

CTDi6514.
ZFINiZDB-GENE-030131-1213. slc2a2.

Phylogenomic databases

eggNOGiKOG0569. Eukaryota.
COG0477. LUCA.
HOVERGENiHBG014816.
KOiK07593.

Miscellaneous databases

NextBioi20807822.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and expression analysis of zebrafish (Danio rerio) GLUT2."
    Diaz M., Planas J.V.
    Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ102R8_DANRE
AccessioniPrimary (citable) accession number: Q102R8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: March 16, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.