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Q10298 (YD44_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein phosphatase C22H10.04

EC=3.1.3.16
Gene names
ORF Names:SPAC22H10.04
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-X subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Putative serine/threonine-protein phosphatase C22H10.04
PRO_0000058918

Sites

Active site1121Proton donor By similarity
Metal binding511Manganese 1 By similarity
Metal binding531Manganese 1 By similarity
Metal binding791Manganese 1 By similarity
Metal binding791Manganese 2 By similarity
Metal binding1111Manganese 2 By similarity
Metal binding1611Manganese 2 By similarity
Metal binding2361Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q10298 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: A13E8B591B7D731F

FASTA30735,178
        10         20         30         40         50         60 
MIDLDNIIER LYEKQLIAES VIAYLCSLAK EVLMQESNVV RLSTPITVVG DIHGQFDDLL 

        70         80         90        100        110        120 
EIFRIGGPCP YTNYLFLGDY VDRGYYSIET ITLLICLKLR YPKRITLLRG NHESRGITQT 

       130        140        150        160        170        180 
YGFYSECLRK YGNANVWKYF TDIFDFLTLS ATIDDTIFCV HGGLSPSIQH IDQILVLDRF 

       190        200        210        220        230        240 
REFPHEGPMA DLVWSDPDPS VQEFSLSPRG AGFSFGEVIV TKFLEYNNMK HILRAHQLCS 

       250        260        270        280        290        300 
EGYQILFEKK LSTVWSAPNY CYRCANLASI LQIDTDQSRF FNVFDAAPNQ ETPFVEPAAK 


VTAEYFL 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAA93605.1.
PIRT38206.
RefSeqNP_593740.1. NM_001019171.2.

3D structure databases

ProteinModelPortalQ10298.
SMRQ10298. Positions 1-306.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid277949. 5 interactions.
STRING4896.SPAC22H10.04-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC22H10.04.1; SPAC22H10.04.1:pep; SPAC22H10.04.
GeneID2541444.
KEGGspo:SPAC22H10.04.

Organism-specific databases

PomBaseSPAC22H10.04.

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000172696.
KOK17615.
OMAFYTECVR.
OrthoDBEOG7FFN29.
PhylomeDBQ10298.

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802546.

Entry information

Entry nameYD44_SCHPO
AccessionPrimary (citable) accession number: Q10298
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names