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Protein

Probable heat shock protein ssa1

Gene

ssa1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATPase activity Source: PomBase
  2. ATP binding Source: UniProtKB-KW
  3. unfolded protein binding Source: PomBase

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. cytoplasmic translation Source: PomBase
  3. protein folding Source: PomBase
  4. protein refolding Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_207307. HSF1-dependent transactivation.
REACT_213398. Regulation of HSF1-mediated heat shock response.
REACT_258506. Attenuation phase.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable heat shock protein ssa1
Gene namesi
Name:ssa1
ORF Names:SPAC13G7.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC13G7.02c.

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytosol Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 644643Probable heat shock protein ssa1PRO_0000078379Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ10265.
PaxDbiQ10265.
PRIDEiQ10265.

Interactioni

Protein-protein interaction databases

BioGridi279320. 52 interactions.
DIPiDIP-54582N.
IntActiQ10265. 2 interactions.
MINTiMINT-4698251.
STRINGi4896.SPAC13G7.02c-1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FP4X-ray2.14Q633-644[»]
ProteinModelPortaliQ10265.
SMRiQ10265. Positions 4-545.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ10265.

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiCOG0443.
HOGENOMiHOG000228135.
InParanoidiQ10265.
KOiK03283.
OMAiDIANPIM.
OrthoDBiEOG728916.
PhylomeDBiQ10265.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q10265-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKSIGIDLG TTYSCVGHFS NNRVEIIAND QGNRTTPSYV AFTDTERLIG
60 70 80 90 100
DAAKNQVAMN PHNTIFDAKR LIGRRFNDPE VQSDMKHWPF KVIEKDGKPL
110 120 130 140 150
IQVEFKGETK TFTPEEISSM VLLKMRESAE AFLGGKVTDA VVTVPAYFND
160 170 180 190 200
SQRQATKDAG LIAGLNVLRI INEPTAAAIA YGLDRSNQHE TNVLIFDLGG
210 220 230 240 250
GTFDVSLLTI EEGIFEVKAT AGDTHLGGED FDSRLVNHFA QEFKRKNKKD
260 270 280 290 300
ITGNARAVRR LRTACERAKR TLSSSAQASI EIDSLYEGID FYTSITRARF
310 320 330 340 350
EELCADLFRN TMEPVEKVLR DSKIDKSSVN EIVLVGGSTR IPRIQKLVSD
360 370 380 390 400
FFNGKEPCKS INPDEAVAYG AAVQAAILVG DTSEKTQDLL LLDVAPLSLG
410 420 430 440 450
IETAGGVMTP LIKRNTTIPT KKSEVFSTYA DNQPGVLIQV FEGERARTKD
460 470 480 490 500
CNLLGKFELS GIPPAPRGVP QIEVTFDVDA NGILNVSALE KGTGKTQKIT
510 520 530 540 550
ITNDKGRLSK EEIDRMVSEA EKYKAEDEAE TSRIQAKNHL ESYAYSLRNS
560 570 580 590 600
LDDPNLKDKV DASDKEAIDK AVKETIEWLD HNTTAAKDEY EDKQKELEGV
610 620 630 640
ANPIMAKIYQ AGGAPGGAPG GMPGGAPGGA PGGADNGPEV EEVD
Length:644
Mass (Da):70,143
Last modified:January 23, 2007 - v2
Checksum:i1AD5E3B18FAC304E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93590.1.
PIRiS67431.
RefSeqiNP_593704.1. NM_001019135.2.

Genome annotation databases

EnsemblFungiiSPAC13G7.02c.1; SPAC13G7.02c.1:pep; SPAC13G7.02c.
GeneIDi2542875.
KEGGispo:SPAC13G7.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93590.1.
PIRiS67431.
RefSeqiNP_593704.1. NM_001019135.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3FP4X-ray2.14Q633-644[»]
ProteinModelPortaliQ10265.
SMRiQ10265. Positions 4-545.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279320. 52 interactions.
DIPiDIP-54582N.
IntActiQ10265. 2 interactions.
MINTiMINT-4698251.
STRINGi4896.SPAC13G7.02c-1.

Proteomic databases

MaxQBiQ10265.
PaxDbiQ10265.
PRIDEiQ10265.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC13G7.02c.1; SPAC13G7.02c.1:pep; SPAC13G7.02c.
GeneIDi2542875.
KEGGispo:SPAC13G7.02c.

Organism-specific databases

PomBaseiSPAC13G7.02c.

Phylogenomic databases

eggNOGiCOG0443.
HOGENOMiHOG000228135.
InParanoidiQ10265.
KOiK03283.
OMAiDIANPIM.
OrthoDBiEOG728916.
PhylomeDBiQ10265.

Enzyme and pathway databases

ReactomeiREACT_207307. HSF1-dependent transactivation.
REACT_213398. Regulation of HSF1-mediated heat shock response.
REACT_258506. Attenuation phase.

Miscellaneous databases

EvolutionaryTraceiQ10265.
NextBioi20803915.
PROiQ10265.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiHSP71_SCHPO
AccessioniPrimary (citable) accession number: Q10265
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: February 4, 2015
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.