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Protein

tRNA (carboxymethyluridine(34)-5-O)-methyltransferase

Gene

trm9

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response (By similarity).By similarity

Catalytic activityi

S-adenosyl-L-methionine + carboxymethyluridine(34) in tRNA = S-adenosyl-L-homocysteine + 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (carboxymethyluridine(34)-5-O)-methyltransferase (EC:2.1.1.229)
Alternative name(s):
tRNA (uracil-5-)-methyltransferase trm9
tRNA [Um34] methyltransferase
tRNA methylase 9
Gene namesi
Name:trm9
ORF Names:SPAC13D6.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC13D6.03c
PomBaseiSPAC13D6.03c trm9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001164891 – 228tRNA (carboxymethyluridine(34)-5-O)-methyltransferaseAdd BLAST228

Proteomic databases

MaxQBiQ10224
PaxDbiQ10224
PRIDEiQ10224

Interactioni

Protein-protein interaction databases

BioGridi279350, 5 interactors
STRINGi4896.SPAC13D6.03c.1

Structurei

3D structure databases

ProteinModelPortaliQ10224
SMRiQ10224
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000209191
InParanoidiQ10224
KOiK15444
OMAiTREYAWP
OrthoDBiEOG092C4H6Z
PhylomeDBiQ10224

Family and domain databases

InterProiView protein in InterPro
IPR013216 Methyltransf_11
IPR029063 SAM-dependent_MTases
IPR032873 Trm9
PANTHERiPTHR13069:SF21 PTHR13069:SF21, 2 hits
PfamiView protein in Pfam
PF08241 Methyltransf_11, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

Q10224-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIEYENEYV HQVYDKIATH FSDTRYKPWP VVEKFLKSLP LGSVGVDIGC
60 70 80 90 100
GNGKYQKVNP NVYMIGSDRC VKLVKIASNL GPMVISDGLH VPHPSNRFDF
110 120 130 140 150
ALSIAVIHHF SNENRRLQAV QEVLRPLVKG GKALFFVWAL EQKNSRRGFS
160 170 180 190 200
EDGPQDVYVP WILKRQYEYP NAKPEELKGH DPAENIAYQR YYHLFRKGEL
210 220
NELVETAGGS ILEHGYDRDN WWVIAEKN
Length:228
Mass (Da):26,277
Last modified:October 1, 1996 - v1
Checksum:i05CC5AD1A53B8C9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93543.1
PIRiT37623
RefSeqiNP_593681.1, NM_001019113.2

Genome annotation databases

EnsemblFungiiSPAC13D6.03c.1; SPAC13D6.03c.1:pep; SPAC13D6.03c
GeneIDi2542906
KEGGispo:SPAC13D6.03c

Similar proteinsi

Entry informationi

Entry nameiTRM9_SCHPO
AccessioniPrimary (citable) accession number: Q10224
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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