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Protein

Septation protein imp2

Gene

imp2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for normal septation. Involved in the disassembly of the medial ring during septation.1 Publication

GO - Molecular functioni

  • phosphatidylinositol-3,4,5-trisphosphate binding Source: PomBase
  • phosphatidylinositol-4-phosphate binding Source: PomBase
  • phosphatidylserine binding Source: PomBase

GO - Biological processi

  • anchoring of the mitotic actomyosin contractile ring to the plasma membrane Source: PomBase
  • mitotic actomyosin contractile ring assembly Source: PomBase

Keywordsi

Biological processCell cycle, Cell division, Mitosis

Names & Taxonomyi

Protein namesi
Recommended name:
Septation protein imp2
Gene namesi
Name:imp2
ORF Names:SPBC11C11.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC11C11.02
PomBaseiSPBC11C11.02 imp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000841861 – 670Septation protein imp2Add BLAST670

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei397Phosphoserine1 Publication1
Modified residuei503Phosphoserine1 Publication1
Modified residuei531Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ10199
PaxDbiQ10199
PRIDEiQ10199

PTM databases

iPTMnetiQ10199

Interactioni

Protein-protein interaction databases

BioGridi276649, 24 interactors
STRINGi4896.SPBC11C11.02.1

Structurei

Secondary structure

1670
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi18 – 21Combined sources4
Helixi28 – 69Combined sources42
Helixi79 – 108Combined sources30
Helixi111 – 165Combined sources55
Helixi166 – 168Combined sources3
Helixi172 – 262Combined sources91
Helixi266 – 277Combined sources12
Beta strandi280 – 284Combined sources5
Helixi292 – 294Combined sources3
Beta strandi304 – 306Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5C1FX-ray2.36A/B15-320[»]
ProteinModelPortaliQ10199
SMRiQ10199
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 269F-BARPROSITE-ProRule annotationAdd BLAST254
Domaini607 – 670SH3PROSITE-ProRule annotationAdd BLAST64

Keywords - Domaini

Coiled coil, SH3 domain

Phylogenomic databases

InParanoidiQ10199
OMAiNNIATLC
OrthoDBiEOG092C3EOZ
PhylomeDBiQ10199

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR001060 FCH_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00611 FCH, 1 hit
PF00018 SH3_1, 1 hit
PRINTSiPR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00055 FCH, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51741 F_BAR, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

Q10199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQQLSFNAS SAKPDKSFSN YFWGANDEGY HALLSRFSDV KHINEELRSF
60 70 80 90 100
YHERANIEED YAKRMAKLSR TTFSSLETGC LKESVQVMKA EVDNMAKSHL
110 120 130 140 150
QISQLLQDDV ENAFTRYAAS LKDKKKMIVS GIEKVHKDKL SKHQALVKAQ
160 170 180 190 200
DKYHYLCKKV NYYVSQQNML FGKELEKNNA KLNKTQNAIT ASSSDYQSAV
210 220 230 240 250
AAVRDSYARW TNEWRSTCDK LQDIEEERRH FLKSVMWTFT LLISRSCFND
260 270 280 290 300
DQACERIRKN LEQCSVSQDV LEFIDAKSTG TGIPQPPKFY DYYKGEVPDD
310 320 330 340 350
SVELVQANFQ RAQTKIENDN MPLNRPYVLS ATARNESSFE NTLPNTPSAI
360 370 380 390 400
QSLTTVSSNS SQNGRSSPKK SFLSKFKLTS RPSTPNVGNT APDALSSPRN
410 420 430 440 450
DSPLTSAADE QMKHLSLQEE PKQNPTPAAP GAFPNSNTLP PRYNELGSLP
460 470 480 490 500
SPNSVSFTED SRPNVNTPSR RQQIQEEFGS VLQMENRAVS PVYDSRKNGS
510 520 530 540 550
RSSFTLRKSR SPKRPSSSLS QNASRLPRSL TPGNLEPNYD FGVRVDPASG
560 570 580 590 600
TAPTDDEPYT DRDSSFVDDT INTKATGNTS NRLSLPAYPT DGGDTSIDNP
610 620 630 640 650
TSTDGQRILG YVSALYDYDA AIPEEISFRK GDTIAVLKLY EDGWWEGFVV
660 670
GEDDHNRGQF PSNFVREIEV
Length:670
Mass (Da):75,167
Last modified:October 1, 1996 - v1
Checksum:i03551FBB56FC91AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA20684.1
PIRiT39317 S67383
RefSeqiNP_596391.1, NM_001022312.2

Genome annotation databases

EnsemblFungiiSPBC11C11.02.1; SPBC11C11.02.1:pep; SPBC11C11.02
GeneIDi2540112
KEGGispo:SPBC11C11.02

Entry informationi

Entry nameiIMP2_SCHPO
AccessioniPrimary (citable) accession number: Q10199
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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