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Q10199

- IMP2_SCHPO

UniProt

Q10199 - IMP2_SCHPO

Protein

Septation protein imp2

Gene

imp2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Required for normal septation. Involved in the disassembly of the medial ring during septation.1 Publication

    GO - Molecular functioni

    1. protein binding Source: PomBase

    GO - Biological processi

    1. actomyosin contractile ring assembly Source: PomBase
    2. mitotic nuclear division Source: UniProtKB-KW

    Keywords - Biological processi

    Cell cycle, Cell division, Mitosis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Septation protein imp2
    Gene namesi
    Name:imp2
    ORF Names:SPBC11C11.02
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome II

    Organism-specific databases

    PomBaseiSPBC11C11.02.

    Subcellular locationi

    Cytoplasmcytoskeleton 1 Publication
    Note: Associates with the medial ring during septation.

    GO - Cellular componenti

    1. actomyosin contractile ring Source: PomBase
    2. cytoplasm Source: PomBase
    3. cytosol Source: PomBase

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 670670Septation protein imp2PRO_0000084186Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei397 – 3971Phosphoserine1 Publication
    Modified residuei503 – 5031Phosphoserine1 Publication
    Modified residuei531 – 5311Phosphothreonine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ10199.

    Interactioni

    Protein-protein interaction databases

    BioGridi276649. 21 interactions.
    MINTiMINT-4697729.
    STRINGi4896.SPBC11C11.02-1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ10199.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9782FCHPROSITE-ProRule annotationAdd
    BLAST
    Domaini607 – 67064SH3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 FCH domain.PROSITE-ProRule annotation
    Contains 1 SH3 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    SH3 domain

    Phylogenomic databases

    eggNOGiNOG303711.
    OMAiFAKSWNS.
    OrthoDBiEOG7F7WKS.
    PhylomeDBiQ10199.

    Family and domain databases

    InterProiIPR001060. FCH_dom.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00611. FCH. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00055. FCH. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS50133. FCH. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q10199-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQQLSFNAS SAKPDKSFSN YFWGANDEGY HALLSRFSDV KHINEELRSF    50
    YHERANIEED YAKRMAKLSR TTFSSLETGC LKESVQVMKA EVDNMAKSHL 100
    QISQLLQDDV ENAFTRYAAS LKDKKKMIVS GIEKVHKDKL SKHQALVKAQ 150
    DKYHYLCKKV NYYVSQQNML FGKELEKNNA KLNKTQNAIT ASSSDYQSAV 200
    AAVRDSYARW TNEWRSTCDK LQDIEEERRH FLKSVMWTFT LLISRSCFND 250
    DQACERIRKN LEQCSVSQDV LEFIDAKSTG TGIPQPPKFY DYYKGEVPDD 300
    SVELVQANFQ RAQTKIENDN MPLNRPYVLS ATARNESSFE NTLPNTPSAI 350
    QSLTTVSSNS SQNGRSSPKK SFLSKFKLTS RPSTPNVGNT APDALSSPRN 400
    DSPLTSAADE QMKHLSLQEE PKQNPTPAAP GAFPNSNTLP PRYNELGSLP 450
    SPNSVSFTED SRPNVNTPSR RQQIQEEFGS VLQMENRAVS PVYDSRKNGS 500
    RSSFTLRKSR SPKRPSSSLS QNASRLPRSL TPGNLEPNYD FGVRVDPASG 550
    TAPTDDEPYT DRDSSFVDDT INTKATGNTS NRLSLPAYPT DGGDTSIDNP 600
    TSTDGQRILG YVSALYDYDA AIPEEISFRK GDTIAVLKLY EDGWWEGFVV 650
    GEDDHNRGQF PSNFVREIEV 670
    Length:670
    Mass (Da):75,167
    Last modified:October 1, 1996 - v1
    Checksum:i03551FBB56FC91AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329671 Genomic DNA. Translation: CAA20684.1.
    PIRiT39317. S67383.
    RefSeqiNP_596391.1. NM_001022312.2.

    Genome annotation databases

    EnsemblFungiiSPBC11C11.02.1; SPBC11C11.02.1:pep; SPBC11C11.02.
    GeneIDi2540112.
    KEGGispo:SPBC11C11.02.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329671 Genomic DNA. Translation: CAA20684.1 .
    PIRi T39317. S67383.
    RefSeqi NP_596391.1. NM_001022312.2.

    3D structure databases

    ProteinModelPortali Q10199.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 276649. 21 interactions.
    MINTi MINT-4697729.
    STRINGi 4896.SPBC11C11.02-1.

    Proteomic databases

    MaxQBi Q10199.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPBC11C11.02.1 ; SPBC11C11.02.1:pep ; SPBC11C11.02 .
    GeneIDi 2540112.
    KEGGi spo:SPBC11C11.02.

    Organism-specific databases

    PomBasei SPBC11C11.02.

    Phylogenomic databases

    eggNOGi NOG303711.
    OMAi FAKSWNS.
    OrthoDBi EOG7F7WKS.
    PhylomeDBi Q10199.

    Miscellaneous databases

    NextBioi 20801248.
    PROi Q10199.

    Family and domain databases

    InterProi IPR001060. FCH_dom.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00611. FCH. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00055. FCH. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS50133. FCH. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "imp2, a new component of the actin ring in the fission yeast Schizosaccharomyces pombe."
      Demeter J., Sazer S.
      J. Cell Biol. 143:415-427(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION.
    2. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397; SER-503 AND THR-531, IDENTIFICATION BY MASS SPECTROMETRY.

    Entry informationi

    Entry nameiIMP2_SCHPO
    AccessioniPrimary (citable) accession number: Q10199
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3