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Protein

Ras modification protein erf4

Gene

erf4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

The erf2-erf4 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization (By similarity). Has a role in meiosis.By similarity1 Publication

GO - Biological processi

Keywordsi

Biological processMeiosis

Names & Taxonomyi

Protein namesi
Recommended name:
Ras modification protein erf4
Alternative name(s):
Meiotically up-regulated gene 91 protein
Gene namesi
Name:erf4
Synonyms:mug91
ORF Names:SPAC3F10.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3F10.07c.
PomBaseiSPAC3F10.07c. erf4.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002139861 – 172Ras modification protein erf4Add BLAST172

Proteomic databases

PRIDEiQ10182.

Interactioni

Subunit structurei

Interacts with erf2.By similarity

Protein-protein interaction databases

BioGridi279545. 42 interactors.
MINTiMINT-4697573.

Family & Domainsi

Sequence similaritiesi

Belongs to the ERF4 family.Curated

Phylogenomic databases

InParanoidiQ10182.
OMAiYHEYISS.
OrthoDBiEOG092C52ZS.
PhylomeDBiQ10182.

Family and domain databases

InterProiView protein in InterPro
IPR019383. Golgin_A_7/ERF4.
PfamiView protein in Pfam
PF10256. Erf4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10182-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVRIERDYS VSGDKYPQFP TDYPVPLRAY VNLEDWDVFI HTLNEKLREA
60 70 80 90 100
FCPWSIGNLL DGILSVLTIY ISEFVFGSIH RKRIGAIDLY ILDFATQHNL
110 120 130 140 150
YVASLRNMGF LSLVFHTKET NSKSSTLHSN PYCPEHHSIR TLPSAVTATT
160 170
SNISTSSSHR SDLPNEWTNS TL
Length:172
Mass (Da):19,595
Last modified:October 1, 1996 - v1
Checksum:iBB3F18D554F6EF96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93305.1.
PIRiT38708.
RefSeqiNP_593939.1. NM_001019367.1.

Genome annotation databases

EnsemblFungiiSPAC3F10.07c.1; SPAC3F10.07c.1:pep; SPAC3F10.07c.
GeneIDi2543113.
KEGGispo:SPAC3F10.07c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93305.1.
PIRiT38708.
RefSeqiNP_593939.1. NM_001019367.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279545. 42 interactors.
MINTiMINT-4697573.

Proteomic databases

PRIDEiQ10182.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3F10.07c.1; SPAC3F10.07c.1:pep; SPAC3F10.07c.
GeneIDi2543113.
KEGGispo:SPAC3F10.07c.

Organism-specific databases

EuPathDBiFungiDB:SPAC3F10.07c.
PomBaseiSPAC3F10.07c. erf4.

Phylogenomic databases

InParanoidiQ10182.
OMAiYHEYISS.
OrthoDBiEOG092C52ZS.
PhylomeDBiQ10182.

Miscellaneous databases

PROiPR:Q10182.

Family and domain databases

InterProiView protein in InterPro
IPR019383. Golgin_A_7/ERF4.
PfamiView protein in Pfam
PF10256. Erf4. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiERFD_SCHPO
AccessioniPrimary (citable) accession number: Q10182
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 12, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.