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Protein

Probable peptidyl-prolyl cis-trans isomerase C27F1.06c

Gene

SPAC27F1.06c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable peptidyl-prolyl cis-trans isomerase C27F1.06c (EC:5.2.1.8)
Short name:
PPIase
Alternative name(s):
Rotamase
Gene namesi
ORF Names:SPAC27F1.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC27F1.06c
PomBaseiSPAC27F1.06c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000753161 – 362Probable peptidyl-prolyl cis-trans isomerase C27F1.06cAdd BLAST362

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei69Phosphoserine1 Publication1
Modified residuei177Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ10175
PaxDbiQ10175
PRIDEiQ10175

PTM databases

iPTMnetiQ10175

Interactioni

Protein-protein interaction databases

BioGridi27798119 interactors.
STRINGi4896.SPAC27F1.06c.1

Structurei

3D structure databases

ProteinModelPortaliQ10175
SMRiQ10175
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini276 – 362PPIase FKBP-typePROSITE-ProRule annotationAdd BLAST87

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000216214
InParanoidiQ10175
KOiK14826
OrthoDBiEOG092C52SD
PhylomeDBiQ10175

Family and domain databases

InterProiView protein in InterPro
IPR026257 FK506_BP
IPR023566 PPIase_FKBP
IPR001179 PPIase_FKBP_dom
PANTHERiPTHR43811 PTHR43811, 1 hit
PfamiView protein in Pfam
PF00254 FKBP_C, 1 hit
PIRSFiPIRSF001473 FK506-bp_FPR3, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q10175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKEETLYSV KVDQERVPLF DEDFYKGFRS ELSVRFTMAA LDPRAKSNDA
60 70 80 90 100
VTVNVITRLE HPEEDGEESD EELFQEEKFT LCTLKKGSVY QQPIDIIFSP
110 120 130 140 150
GEEVFFERVG GDIPVYLSGT CIITNIPEEE DSSDLENDFL YGADEFSSDE
160 170 180 190 200
EEMDDISVTS SEEEEEENGA RIEELNSDEE DAEQAEEEIL EKPVPKDEVA
210 220 230 240 250
EKHSKDKLKK EEKEKKTAVD VSDSVNGKKR KTEPAGEGEQ TEKKSKSTKT
260 270 280 290 300
YPKQVLEGNV TVQDKVKGDG PAAKRKKRVS MRYIGRLTNG KVFDKNITGK
310 320 330 340 350
PFTFNLGLEE VIKGWDVGIV GMQVGGERTI HIPAAMAYGS KRLPGIPANS
360
DLVFDVKLLA VN
Length:362
Mass (Da):40,540
Last modified:October 1, 1996 - v1
Checksum:i88F1785FB95A7B8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93295.1
PIRiT38464
RefSeqiNP_594535.1, NM_001019964.2

Genome annotation databases

EnsemblFungiiSPAC27F1.06c.1; SPAC27F1.06c.1:pep; SPAC27F1.06c
GeneIDi2541479
KEGGispo:SPAC27F1.06c

Similar proteinsi

Entry informationi

Entry nameiFKBPH_SCHPO
AccessioniPrimary (citable) accession number: Q10175
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome