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Protein

Probable prefoldin subunit 3

Gene

SPAC3H8.07c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable prefoldin subunit 3
Gene namesi
ORF Names:SPAC3H8.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3H8.07c.
PomBaseiSPAC3H8.07c.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • prefoldin complex Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 169169Probable prefoldin subunit 3PRO_0000153658Add
BLAST

Proteomic databases

MaxQBiQ10143.

Interactioni

Subunit structurei

Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.By similarity

Protein-protein interaction databases

BioGridi279800. 105 interactions.
MINTiMINT-4697226.

Structurei

3D structure databases

ProteinModelPortaliQ10143.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prefoldin subunit alpha family.Curated

Phylogenomic databases

HOGENOMiHOG000184744.
InParanoidiQ10143.
OMAiDEQHSKY.
OrthoDBiEOG7DRJFG.
PhylomeDBiQ10143.

Family and domain databases

Gene3Di1.10.287.370. 1 hit.
InterProiIPR016655. PFD3.
IPR009053. Prefoldin.
IPR004127. Prefoldin_subunit_alpha.
[Graphical view]
PANTHERiPTHR12409. PTHR12409. 1 hit.
PfamiPF02996. Prefoldin. 1 hit.
[Graphical view]
PIRSFiPIRSF016396. Prefoldin_subunit_3. 1 hit.
SUPFAMiSSF46579. SSF46579. 1 hit.

Sequencei

Sequence statusi: Complete.

Q10143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSNPRGIP PAQFFEFKEL SMEEAQGHLE KFQEAIAKYK FMETSVVRRV
60 70 80 90 100
ASLDDKIPDI RKTLQSVQFL KERQGDSFTV TYELNDTLNA KAEVEAKDNV
110 120 130 140 150
YLWLGANVML EYTVEEAEAL LTQKLNSAEE TLKACKEDLE FLRAQVTTME
160
VNTARVYNYT VLLRKKTKM
Length:169
Mass (Da):19,445
Last modified:October 1, 1996 - v1
Checksum:i1AFED3448E823B22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93164.1.
PIRiT38765.
RefSeqiNP_593000.1. NM_001018399.2.

Genome annotation databases

EnsemblFungiiSPAC3H8.07c.1; SPAC3H8.07c.1:pep; SPAC3H8.07c.
GeneIDi2543378.
KEGGispo:SPAC3H8.07c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA93164.1.
PIRiT38765.
RefSeqiNP_593000.1. NM_001018399.2.

3D structure databases

ProteinModelPortaliQ10143.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279800. 105 interactions.
MINTiMINT-4697226.

Proteomic databases

MaxQBiQ10143.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3H8.07c.1; SPAC3H8.07c.1:pep; SPAC3H8.07c.
GeneIDi2543378.
KEGGispo:SPAC3H8.07c.

Organism-specific databases

EuPathDBiFungiDB:SPAC3H8.07c.
PomBaseiSPAC3H8.07c.

Phylogenomic databases

HOGENOMiHOG000184744.
InParanoidiQ10143.
OMAiDEQHSKY.
OrthoDBiEOG7DRJFG.
PhylomeDBiQ10143.

Miscellaneous databases

PROiQ10143.

Family and domain databases

Gene3Di1.10.287.370. 1 hit.
InterProiIPR016655. PFD3.
IPR009053. Prefoldin.
IPR004127. Prefoldin_subunit_alpha.
[Graphical view]
PANTHERiPTHR12409. PTHR12409. 1 hit.
PfamiPF02996. Prefoldin. 1 hit.
[Graphical view]
PIRSFiPIRSF016396. Prefoldin_subunit_3. 1 hit.
SUPFAMiSSF46579. SSF46579. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiPFD3_SCHPO
AccessioniPrimary (citable) accession number: Q10143
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 8, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.