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Protein

Probable prefoldin subunit 3

Gene

SPAC3H8.07c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable prefoldin subunit 3
Gene namesi
ORF Names:SPAC3H8.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3H8.07c
PomBaseiSPAC3H8.07c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001536581 – 169Probable prefoldin subunit 3Add BLAST169

Proteomic databases

MaxQBiQ10143
PaxDbiQ10143
PRIDEiQ10143

Interactioni

Subunit structurei

Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi279800, 105 interactors
STRINGi4896.SPAC3H8.07c.1

Structurei

3D structure databases

ProteinModelPortaliQ10143
SMRiQ10143
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prefoldin subunit alpha family.Curated

Phylogenomic databases

HOGENOMiHOG000184744
InParanoidiQ10143
OMAiQITVMEV
OrthoDBiEOG092C4ZF5
PhylomeDBiQ10143

Family and domain databases

Gene3Di1.10.287.370, 1 hit
InterProiView protein in InterPro
IPR016655 PFD3
IPR009053 Prefoldin
IPR004127 Prefoldin_subunit_alpha
PANTHERiPTHR12409 PTHR12409, 1 hit
PfamiView protein in Pfam
PF02996 Prefoldin, 1 hit
PIRSFiPIRSF016396 Prefoldin_subunit_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q10143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSNPRGIP PAQFFEFKEL SMEEAQGHLE KFQEAIAKYK FMETSVVRRV
60 70 80 90 100
ASLDDKIPDI RKTLQSVQFL KERQGDSFTV TYELNDTLNA KAEVEAKDNV
110 120 130 140 150
YLWLGANVML EYTVEEAEAL LTQKLNSAEE TLKACKEDLE FLRAQVTTME
160
VNTARVYNYT VLLRKKTKM
Length:169
Mass (Da):19,445
Last modified:October 1, 1996 - v1
Checksum:i1AFED3448E823B22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93164.1
PIRiT38765
RefSeqiNP_593000.1, NM_001018399.2

Genome annotation databases

EnsemblFungiiSPAC3H8.07c.1; SPAC3H8.07c.1:pep; SPAC3H8.07c
GeneIDi2543378
KEGGispo:SPAC3H8.07c

Similar proteinsi

Entry informationi

Entry nameiPFD3_SCHPO
AccessioniPrimary (citable) accession number: Q10143
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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