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Q10088

- SPEB1_SCHPO

UniProt

Q10088 - SPEB1_SCHPO

Protein

Putative agmatinase 1

Gene

SPAC11D3.09

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Agmatine + H2O = putrescine + urea.

    Cofactori

    Manganese.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi186 – 1861Manganese 1PROSITE-ProRule annotation
    Metal bindingi209 – 2091Manganese 1PROSITE-ProRule annotation
    Metal bindingi209 – 2091Manganese 2PROSITE-ProRule annotation
    Metal bindingi211 – 2111Manganese 2PROSITE-ProRule annotation
    Metal bindingi213 – 2131Manganese 1PROSITE-ProRule annotation
    Metal bindingi307 – 3071Manganese 1PROSITE-ProRule annotation
    Metal bindingi307 – 3071Manganese 2PROSITE-ProRule annotation
    Metal bindingi309 – 3091Manganese 2PROSITE-ProRule annotation

    GO - Molecular functioni

    1. agmatinase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cellular amino acid metabolic process Source: PomBase

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative agmatinase 1 (EC:3.5.3.11)
    Alternative name(s):
    Agmatine ureohydrolase 1
    Short name:
    AUH 1
    Gene namesi
    ORF Names:SPAC11D3.09
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC11D3.09.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: PomBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 394374Putative agmatinase 1PRO_0000002091Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    BioGridi278065. 3 interactions.
    MINTiMINT-4696816.
    STRINGi4896.SPAC11D3.09-1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ10088.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the arginase family.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG0010.
    HOGENOMiHOG000204320.
    KOiK01480.
    OMAiTYFYWAS.
    OrthoDBiEOG718KPD.
    PhylomeDBiQ10088.

    Family and domain databases

    Gene3Di3.40.800.10. 1 hit.
    InterProiIPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view]
    PANTHERiPTHR11358. PTHR11358. 1 hit.
    PfamiPF00491. Arginase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036979. Arginase. 1 hit.
    PRINTSiPR00116. ARGINASE.
    PROSITEiPS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q10088-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALQSLFLIL LAGAAQLAQA HPKIFEQSRA NAVETFDDAF PGDGETQADS    50
    VFSGIATFGR LPYWKCLNDK SQSFDIAFLG APFDTGTSYR PGARFGPSGI 100
    REGSRRLNLY GGYNVPMETN PFNNWAKIVD CGDIPLTSYD NAVAIKQIEN 150
    GHFELLTRKP TSYSEKDGYA LDGSVLPRVI TLGGDHTIVL PILRSVSRAY 200
    GPVSIIHFDS HLDSWKPKVF GGGKSSVGSI NHGTYFYHAS QEGLVSNDSN 250
    IHAGIRTTLS GLSDYDNDAD CGFEIIEARE IDTIGIDAII KRIRDRVGDG 300
    IAYLSIDIDV LDPAYAPATG TPESAGWTTR ELRTILRGLD GIKLVGADIV 350
    EVAPAYDFAE VTTLAAADIL FEVMSIMVKT PVYKEQAKQQ SRFY 394
    Length:394
    Mass (Da):42,879
    Last modified:February 1, 1996 - v1
    Checksum:iD6CFFBF3945C5036
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAA92310.1.
    PIRiT37520.
    RefSeqiNP_592806.1. NM_001018206.2.

    Genome annotation databases

    EnsemblFungiiSPAC11D3.09.1; SPAC11D3.09.1:pep; SPAC11D3.09.
    GeneIDi2541568.
    KEGGispo:SPAC11D3.09.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAA92310.1 .
    PIRi T37520.
    RefSeqi NP_592806.1. NM_001018206.2.

    3D structure databases

    ProteinModelPortali Q10088.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 278065. 3 interactions.
    MINTi MINT-4696816.
    STRINGi 4896.SPAC11D3.09-1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC11D3.09.1 ; SPAC11D3.09.1:pep ; SPAC11D3.09 .
    GeneIDi 2541568.
    KEGGi spo:SPAC11D3.09.

    Organism-specific databases

    PomBasei SPAC11D3.09.

    Phylogenomic databases

    eggNOGi COG0010.
    HOGENOMi HOG000204320.
    KOi K01480.
    OMAi TYFYWAS.
    OrthoDBi EOG718KPD.
    PhylomeDBi Q10088.

    Miscellaneous databases

    NextBioi 20802662.

    Family and domain databases

    Gene3Di 3.40.800.10. 1 hit.
    InterProi IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view ]
    PANTHERi PTHR11358. PTHR11358. 1 hit.
    Pfami PF00491. Arginase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036979. Arginase. 1 hit.
    PRINTSi PR00116. ARGINASE.
    PROSITEi PS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiSPEB1_SCHPO
    AccessioniPrimary (citable) accession number: Q10088
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3