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Q0ZUP1 (KLRB1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Killer cell lectin-like receptor subfamily B member 1
Alternative name(s):
Killer cell lectin-like receptor subfamily B member 1G
Natural killer cell surface protein NKR-P1G
Natural killer lectin-like receptor 1E
Gene names
Name:Klrb1
Synonyms:Gm4696, Klrb1d, Klrb1g, Klrb6, Nkrp1g
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass type II membrane protein Potential.

Sequence similarities

Contains 1 C-type lectin domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Killer cell lectin-like receptor subfamily B member 1
PRO_0000317213

Regions

Topological domain1 – 4242Cytoplasmic Potential
Transmembrane43 – 6321Helical; Signal-anchor for type II membrane protein; Potential
Topological domain64 – 214151Extracellular Potential
Domain98 – 208111C-type lectin

Amino acid modifications

Disulfide bond119 ↔ 207 By similarity
Disulfide bond186 ↔ 199 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0ZUP1 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 79DEC281E49943DF

FASTA21423,909
        10         20         30         40         50         60 
MDAPVLYAEL NLAETRGLRC TSAPSLPQDA CQGPGWHRVA LKLGCAGLIF LLMVLSVLVG 

        70         80         90        100        110        120 
FLVQKPLIEK CSVAVQENRT EPTGRSATLE CPRDWHPHCD KCLFTSQTSR PWADGLVDCN 

       130        140        150        160        170        180 
LKGATLLLIQ DEEELRLLQN FSKGKGQQFY IGLKYEEVDK VWKWMNGSIL NTNLLQITGK 

       190        200        210 
DEENSCALIS QTEVFSDSCS SDNHWICQKT LKHV 

« Hide

References

[1]"Gene homogenization of exons encoding the ligand binding parts of regulatory leukocyte receptors."
Fossum S., Flornes L.M., Saether P.C., Dissen E.
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6.
[2]"Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells."
Carlyle J.R., Mesci A., Ljutic B., Belanger S., Tai L.-H., Rousselle E., Troke A.D., Proteau M.-F., Makrigiannis A.P.
J. Immunol. 176:7511-7524(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 60-174.
Strain: BALB/c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ113419 mRNA. Translation: ABA41355.1.
DQ336141 Genomic DNA. Translation: ABC71751.1.
RefSeqNP_001093388.1. NM_001099918.1.
UniGeneMm.66911.

3D structure databases

ProteinModelPortalQ0ZUP1.
SMRQ0ZUP1. Positions 89-211.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000107738.

Proteomic databases

PRIDEQ0ZUP1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000112110; ENSMUSP00000107738; ENSMUSG00000079299.
GeneID100043861.
KEGGmmu:100043861.
UCSCuc009eem.1. mouse.

Organism-specific databases

CTD3820.
MGIMGI:96877. Klrb1.

Phylogenomic databases

eggNOGNOG307083.
GeneTreeENSGT00730000110837.
HOGENOMHOG000074586.
HOVERGENHBG052267.
InParanoidQ0ZUP1.
KOK06543.
OMAWHRVALK.
OrthoDBEOG7J4487.
PhylomeDBQ0ZUP1.
TreeFamTF337735.

Gene expression databases

BgeeQ0ZUP1.
GenevestigatorQ0ZUP1.

Family and domain databases

Gene3D3.10.100.10. 1 hit.
InterProIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
[Graphical view]
PfamPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMSSF56436. SSF56436. 1 hit.
PROSITEPS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio457273.
PROQ0ZUP1.
SOURCESearch...

Entry information

Entry nameKLRB1_MOUSE
AccessionPrimary (citable) accession number: Q0ZUP1
Secondary accession number(s): Q1A4F6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot