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Protein

Killer cell lectin-like receptor subfamily B member 1

Gene

Klrb1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandLectin

Enzyme and pathway databases

ReactomeiR-RNO-198933. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.

Names & Taxonomyi

Protein namesi
Recommended name:
Killer cell lectin-like receptor subfamily B member 1
Alternative name(s):
Immunoreceptor NKR-P1E
Killer cell lectin-like receptor subfamily B member 1G
Natural killer cell surface protein NKR-P1G
Natural killer lectin-like receptor 1E
Gene namesi
Name:Klrb1
Synonyms:Klrb1dImported, Klrb1g, Klrb6Imported, Nkrp1eImported, Nkrp1g1 Publication
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1587563. Klrb1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 42CytoplasmicSequence analysisAdd BLAST42
Transmembranei43 – 63Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini64 – 214ExtracellularSequence analysisAdd BLAST151

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172141 – 214Killer cell lectin-like receptor subfamily B member 1Add BLAST214

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi119 ↔ 207PROSITE-ProRule annotation
Disulfide bondi186 ↔ 199PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ0ZUP0.
PRIDEiQ0ZUP0.

Expressioni

Gene expression databases

BgeeiENSRNOG00000057410.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000036493.

Structurei

3D structure databases

ProteinModelPortaliQ0ZUP0.
SMRiQ0ZUP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini98 – 208C-type lectinPROSITE-ProRule annotationAdd BLAST111

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
GeneTreeiENSGT00730000110837.
HOGENOMiHOG000074586.
HOVERGENiHBG052267.
InParanoidiQ0ZUP0.
KOiK06543.
OMAiWHRVALK.
OrthoDBiEOG091G0QVA.
PhylomeDBiQ0ZUP0.
TreeFamiTF337735.

Family and domain databases

CDDicd03593. CLECT_NK_receptors_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link_sf.
IPR016187. CTDL_fold.
IPR033992. NKR-like_CTLD.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0ZUP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAPVLYAEL HLANTQGLRC TSPPSPRQDA CWGSGWHRVA LKLGCVGLIL
60 70 80 90 100
LLMGLSVLVG FLVQKPPIEK CSVAVQENKT EPTVRSTILE CPRDWHLHWN
110 120 130 140 150
KCLFISQTSR PWAEGLADCS LRGATLLLIG DGKELKLLQD FSKGKGQQFF
160 170 180 190 200
IGLKYVQEDK VWKWMNGSIL NTNLLRITGK NEENSCALIS HTEVFSDSCS
210
SDNHWICQKT LKRV
Length:214
Mass (Da):23,963
Last modified:August 22, 2006 - v1
Checksum:iCE2AC7D1C9417D90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ157011 mRNA. Translation: ABA40405.1.
DQ157012 mRNA. Translation: ABA40406.1.
DQ113420 mRNA. Translation: ABA41356.1.
EF100680 mRNA. Translation: ABO15820.1.
RefSeqiNP_001078874.1. NM_001085405.1.
UniGeneiRn.198693.

Genome annotation databases

EnsembliENSRNOT00000084289; ENSRNOP00000072670; ENSRNOG00000057410.
GeneIDi689817.
KEGGirno:689817.
UCSCiRGD:1587563. rat.

Similar proteinsi

Entry informationi

Entry nameiKLRB1_RAT
AccessioniPrimary (citable) accession number: Q0ZUP0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: November 22, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome