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Q0ZS46

- GST_PLAVI

UniProt

Q0ZS46 - GST_PLAVI

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Protein
Glutathione S-transferase
Gene
GST
Organism
Plasmodium vivax
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91Glutathione By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase (EC:2.5.1.18)
    Gene namesi
    Name:GST
    OrganismiPlasmodium vivax
    Taxonomic identifieri5855 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Plasmodium)

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 205205Glutathione S-transferase
    PRO_0000259968Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer By similarity.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0ZS46.
    SMRiQ0ZS46. Positions 1-205.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 8785GST N-terminal
    Add
    BLAST
    Domaini89 – 205117GST C-terminal
    Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni58 – 592Glutathione binding By similarity
    Regioni71 – 722Glutathione binding By similarity

    Sequence similaritiesi

    Belongs to the GST superfamily.

    Phylogenomic databases

    eggNOGiNOG122057.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q0ZS46-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEEIVLYYF DARGKAELIR LIFAYLGIQY TDKRFGENGD AFIEFKNFKK    50
    EKETPFNQVP ILEMDNIIFA QSQAIVRYLS KKYKISGNSE LNEFYADMIF 100
    CGVQDIHYKF NNTNLFKQNE TTFLNEELPK WSGYFENILK KNNCNYFVGD 150
    DLTYADLAVF NLYDDIETKY PNSLKNFPLL KAHNEFISNL PNIKNYISNR 200
    KESVY 205
    Length:205
    Mass (Da):24,212
    Last modified:August 22, 2006 - v1
    Checksum:iEF4AA17C428624FA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ156544 mRNA. Translation: ABA40394.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ156544 mRNA. Translation: ABA40394.1 .

    3D structure databases

    ProteinModelPortali Q0ZS46.
    SMRi Q0ZS46. Positions 1-205.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG122057.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of glutathione S-transferase from Plasmodium vivax."
      Na B.-K., Kong Y., Kim T.-S.
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiGST_PLAVI
    AccessioniPrimary (citable) accession number: Q0ZS46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 14, 2006
    Last sequence update: August 22, 2006
    Last modified: April 16, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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