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Q0ZS46 (GST_PLAVI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase

EC=2.5.1.18
Gene names
Name:GST
OrganismPlasmodium vivax
Taxonomic identifier5855 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Plasmodium)

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the GST superfamily.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205Glutathione S-transferase
PRO_0000259968

Regions

Domain3 – 8785GST N-terminal
Domain89 – 205117GST C-terminal
Region58 – 592Glutathione binding By similarity
Region71 – 722Glutathione binding By similarity

Sites

Binding site91Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0ZS46 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: EF4AA17C428624FA

FASTA20524,212
        10         20         30         40         50         60 
MAEEIVLYYF DARGKAELIR LIFAYLGIQY TDKRFGENGD AFIEFKNFKK EKETPFNQVP 

        70         80         90        100        110        120 
ILEMDNIIFA QSQAIVRYLS KKYKISGNSE LNEFYADMIF CGVQDIHYKF NNTNLFKQNE 

       130        140        150        160        170        180 
TTFLNEELPK WSGYFENILK KNNCNYFVGD DLTYADLAVF NLYDDIETKY PNSLKNFPLL 

       190        200 
KAHNEFISNL PNIKNYISNR KESVY 

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References

[1]"Identification and characterization of glutathione S-transferase from Plasmodium vivax."
Na B.-K., Kong Y., Kim T.-S.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ156544 mRNA. Translation: ABA40394.1.

3D structure databases

ProteinModelPortalQ0ZS46.
SMRQ0ZS46. Positions 1-205.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG122057.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGST_PLAVI
AccessionPrimary (citable) accession number: Q0ZS46
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: August 22, 2006
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families