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Q0ZS46

- GST_PLAVI

UniProt

Q0ZS46 - GST_PLAVI

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Protein

Glutathione S-transferase

Gene
GST
Organism
Plasmodium vivax
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91Glutathione By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase (EC:2.5.1.18)
Gene namesi
Name:GST
OrganismiPlasmodium vivax
Taxonomic identifieri5855 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Plasmodium)

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205Glutathione S-transferasePRO_0000259968Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ0ZS46.
SMRiQ0ZS46. Positions 1-205.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 8785GST N-terminalAdd
BLAST
Domaini89 – 205117GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni58 – 592Glutathione binding By similarity
Regioni71 – 722Glutathione binding By similarity

Sequence similaritiesi

Belongs to the GST superfamily.

Phylogenomic databases

eggNOGiNOG122057.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0ZS46-1 [UniParc]FASTAAdd to Basket

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MAEEIVLYYF DARGKAELIR LIFAYLGIQY TDKRFGENGD AFIEFKNFKK    50
EKETPFNQVP ILEMDNIIFA QSQAIVRYLS KKYKISGNSE LNEFYADMIF 100
CGVQDIHYKF NNTNLFKQNE TTFLNEELPK WSGYFENILK KNNCNYFVGD 150
DLTYADLAVF NLYDDIETKY PNSLKNFPLL KAHNEFISNL PNIKNYISNR 200
KESVY 205
Length:205
Mass (Da):24,212
Last modified:August 22, 2006 - v1
Checksum:iEF4AA17C428624FA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ156544 mRNA. Translation: ABA40394.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ156544 mRNA. Translation: ABA40394.1 .

3D structure databases

ProteinModelPortali Q0ZS46.
SMRi Q0ZS46. Positions 1-205.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi NOG122057.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of glutathione S-transferase from Plasmodium vivax."
    Na B.-K., Kong Y., Kim T.-S.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiGST_PLAVI
AccessioniPrimary (citable) accession number: Q0ZS46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 14, 2006
Last sequence update: August 22, 2006
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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