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Protein
Submitted name:

MLH1-Ex(9-10) isoform

Gene

MLH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. mismatched DNA binding Source: InterPro

GO - Biological processi

  1. mismatch repair Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MLH1-Ex(9-10) isoformImported
Gene namesi
Name:MLH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. mismatch repair complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ0ZAJ5.

Structurei

3D structure databases

ProteinModelPortaliQ0ZAJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000176000.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
InterProiIPR013507. DNA_mismatch_repair_C.
IPR011186. DNA_mismatch_repair_MLH1/HexB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PANTHERiPTHR10073:SF12. PTHR10073:SF12. 1 hit.
PfamiPF01119. DNA_mis_repair. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q0ZAJ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LPNASTVDNI RSIFGNAVSR LEISPQNVDV NVHPTKHEVH FLHEESIPER
60 70 80 90 100
VQQHIESKLL GSNPSRMYFT QTLLPGLAGP SGEMVKSTTS LTSSSTSGSS
110 120 130 140 150
NKVYAHQMVR TDSREQKLDA FLQPLSKPLS SQPQAIVTED KTDISSGRAR
160 170 180
QQDEEMLELP APAEVAAKNQ SLEGDTTKGT SEMS
Length:184
Mass (Da):20,055
Last modified:August 22, 2006 - v1
Checksum:iBC7D6B05427BB7CD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei184 – 1841Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ648891 mRNA. Translation: ABG49486.1.
UniGeneiHs.195364.

Genome annotation databases

UCSCiuc010hgg.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ648891 mRNA. Translation: ABG49486.1.
UniGeneiHs.195364.

3D structure databases

ProteinModelPortaliQ0ZAJ5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ0ZAJ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc010hgg.1. human.

Phylogenomic databases

HOGENOMiHOG000176000.

Miscellaneous databases

ChiTaRSiMLH1. human.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
InterProiIPR013507. DNA_mismatch_repair_C.
IPR011186. DNA_mismatch_repair_MLH1/HexB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PANTHERiPTHR10073:SF12. PTHR10073:SF12. 1 hit.
PfamiPF01119. DNA_mis_repair. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "EASI--enrichment of alternatively spliced isoforms."
    Venables J.P., Burn J.
    Nucleic Acids Res. 34:e103-e103(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ0ZAJ5_HUMAN
AccessioniPrimary (citable) accession number: Q0ZAJ5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: November 26, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.