Q0WXX5 (Q0WXX5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Kallikrein 11 isoform 1 EMBL BAF02733.1

Submitted name:
Kallikrein 11, isoform CRA_b EMBL EAW71971.1

Gene names

Name:	KLK11 EMBL BAF02733.1
ORF Names:	hCG_22935 EMBL EAW71971.1

Organism

Homo sapiens (Human) EMBL BAF02733.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease RuleBase RU004260
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0WXX5 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 192D910BBCDC7A56	FASTA	250	27,466
	10 20 30 40 50 60 MRILQLILLA LATGLVGGET RIIKGFECKP HSQPWQAALF EKTRLLCGAT LIAPRWLLTA 70 80 90 100 110 120 AHCLKPRYIV HLGQHNLQKE EGCEQTRTAT ESFPHPGFNN SLPNKDHRND IMLVKMASPV 130 140 150 160 170 180 SITWAVRPLT LSSRCVTAGT SCLISGWGST SSPQLRLPHT LRCANITIIE HQKCENAYPG 190 200 210 220 230 240 NITDTMVCAS VQEGGKDSCQ GDSGGPLVCN QSLQGIISWG QDPCAITRKP GVYTKVCKYV 250 DWIQETMKNN

References

[1]	"Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasin." Mitsui S., Nakamura T., Okui A., Kominami K., Uemura H., Yamaguchi N. FEBS J. 273:3678-3686(2006) [PubMed: 16911518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB259014 mRNA. Translation: BAF02733.1. CH471135 Genomic DNA. Translation: EAW71971.1.
IPI	IPI00002818.
RefSeq	NP_001129504.1. NM_001136032.2. NP_006844.1. NM_006853.2.
UniGene	Hs.57771.
3D structure databases
ProteinModelPortal	Q0WXX5.
SMR	Q0WXX5. Positions 22-248.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0WXX5.
Proteomic databases
PRIDE	Q0WXX5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	11012.
KEGG	hsa:11012.
Organism-specific databases
CTD	11012.
PharmGKB	PA30148.
Phylogenomic databases
GeneTree	ENSGT00590000082811.
HOVERGEN	HBG013304.
Gene expression databases
ArrayExpress	Q0WXX5.
Bgee	Q0WXX5.
Family and domain databases
InterPro	IPR009003. Pept_cys/ser_Trypsin-like. IPR018114. Peptidase_S1/S6_AS. IPR001254. Peptidase_S1_S6. IPR001314. Peptidase_S1A. [Graphical view]
KO	K09620.
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
PRINTS	PR00722. CHYMOTRYPSIN.
SMART	SM00020. Tryp_SPc. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
PROSITE	PS50240. TRYPSIN_DOM. 1 hit. PS00134. TRYPSIN_HIS. 1 hit. PS00135. TRYPSIN_SER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	41831.
PMAP-CutDB	Q0WXX5.

Entry information

Entry name

Q0WXX5_HUMAN

Accession

Primary (citable) accession number: Q0WXX5

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.