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Protein

Coatomer subunit gamma

Gene

At4g34450

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-6807878 COPI-mediated anterograde transport
R-ATH-6811434 COPI-dependent Golgi-to-ER retrograde traffic

Names & Taxonomyi

Protein namesi
Recommended name:
Coatomer subunit gamma
Alternative name(s):
Gamma-coat protein
Short name:
Gamma-COP
Gene namesi
Ordered Locus Names:At4g34450
ORF Names:T4L20.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G34450
TAIRilocus:2139479 AT4G34450

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002856271 – 886Coatomer subunit gammaAdd BLAST886

Proteomic databases

PaxDbiQ0WW26
PRIDEiQ0WW26

PTM databases

iPTMnetiQ0WW26
SwissPalmiQ0WW26

Expressioni

Gene expression databases

ExpressionAtlasiQ0WW26 baseline and differential
GenevisibleiQ0WW26 AT

Interactioni

Subunit structurei

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.By similarity

Protein-protein interaction databases

BioGridi14878, 3 interactors
IntActiQ0WW26, 1 interactor
STRINGi3702.AT4G34450.1

Structurei

3D structure databases

ProteinModelPortaliQ0WW26
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati66 – 103HEAT 1Add BLAST38
Repeati288 – 325HEAT 2Add BLAST38
Repeati327 – 359HEAT 3Add BLAST33
Repeati360 – 397HEAT 4Add BLAST38
Repeati472 – 509HEAT 5Add BLAST38

Sequence similaritiesi

Belongs to the COPG family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
HOGENOMiHOG000184434
InParanoidiQ0WW26
KOiK17267
OMAiKSEMVNF
OrthoDBiEOG093601RJ
PhylomeDBiQ0WW26

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

Sequencei

Sequence statusi: Complete.

Q0WW26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQPLVKKDD DHDDELEYSP FMGIEKGAVL QEARVFNDPQ VDPRRCSQVI
60 70 80 90 100
TKLLYLLNQG ESFTKVEATE VFFSVTKLFQ SKDTGLRRMV YLIIKELSPS
110 120 130 140 150
SDEVIIVTSS LMKDMNSKID MYRANAIRVL CRIIDGTLLT QIERYLKQAI
160 170 180 190 200
VDKNPVVSSA ALVSGLHLLK TNPEIVKRWS NEVQEGIQSR SALVQFHALA
210 220 230 240 250
LLHQIRQNDR LAVSKLVGSL TRGSVRSPLA QCLLIRYTSQ VIRDMANHGQ
260 270 280 290 300
SGERPFYEFL ESCLRHKAEM VILEAARAIT ELDGVTSREL TPAITVLQLF
310 320 330 340 350
LSSPRPVLRF AAVRTLNKVA MTHPMAVTNC NIDMESLISD QNRSIATLAI
360 370 380 390 400
TTLLKTGNES SVERLMKQIT NFMSDIADEF KIVVVDAIRS LCVKFPLKYR
410 420 430 440 450
SLMTFLSNIL REEGGFEYKR AIVDSIVTII RDIPDAKESG LLHLCEFIED
460 470 480 490 500
CEFTYLSTQI LHFLGIEGPN TSDPSKYIRY IYNRVHLENA TVRAAAVSTL
510 520 530 540 550
AKFGFMVESL KPRITVLLKR CIYDSDDEVR DRATLYLSVL GGDGTVDTDK
560 570 580 590 600
ESKDFLFGSL EVPLVNMETS LKNYEPSEEA FDINSVPKEV KSQPLAEKKA
610 620 630 640 650
QGKKPTGLGA PPAAPASGFD GYERLLSSIP EFAAFGKLFK SSLPVELTEA
660 670 680 690 700
ETEYAVNVVK HIFDSHVVFQ YNCTNTIPEQ LLERVNVIVD ASEAEEFSEV
710 720 730 740 750
TSKALNSLPY DSPGQAFVVF EKPAGVPAVG KFSNTLTFVV KEVDPSTGEA
760 770 780 790 800
EDDGVEDEYQ LEDLEVVAGD YMVKVGVSNF RNAWESMDEE DERVDEYGLG
810 820 830 840 850
QRESLGEAVK AVMDLLGMQT CEGTETIPLN ARSHTCLLSG VYIGNVKVLV
860 870 880
RAQFGMDSSK DIAMKLTVRA EDVSVAEAIH EIVASG
Length:886
Mass (Da):98,491
Last modified:May 1, 2007 - v2
Checksum:i188840F332D97CAF
GO

Sequence cautioni

The sequence CAA18824 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80162 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023094 Genomic DNA Translation: CAA18824.1 Sequence problems.
AL161585 Genomic DNA Translation: CAB80162.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86378.1
AK221839 mRNA Translation: BAD94079.1
AK226533 mRNA Translation: BAE98672.1
PIRiT05265
RefSeqiNP_195171.2, NM_119610.4
UniGeneiAt.25572

Genome annotation databases

EnsemblPlantsiAT4G34450.1; AT4G34450.1; AT4G34450
GeneIDi829596
GrameneiAT4G34450.1; AT4G34450.1; AT4G34450
KEGGiath:AT4G34450

Similar proteinsi

Entry informationi

Entry nameiCOPG_ARATH
AccessioniPrimary (citable) accession number: Q0WW26
Secondary accession number(s): O65673, Q56X38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: April 25, 2018
This is version 98 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health