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Protein

Probable LRR receptor-like serine/threonine-protein kinase At2g23950

Gene

At2g23950

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei327ATPPROSITE-ProRule annotation1
Active sitei422Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi305 – 313ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable LRR receptor-like serine/threonine-protein kinase At2g23950 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At2g23950
ORF Names:T29E15.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G23950.
TAIRilocus:2061466. AT2G23950.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 236ExtracellularSequence analysisAdd BLAST209
Transmembranei237 – 257HelicalSequence analysisAdd BLAST21
Topological domaini258 – 634CytoplasmicSequence analysisAdd BLAST377

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000038754728 – 634Probable LRR receptor-like serine/threonine-protein kinase At2g23950Add BLAST607

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi96N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi109N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi155N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei296PhosphothreonineBy similarity1
Modified residuei322PhosphothreonineBy similarity1
Modified residuei380PhosphoserineBy similarity1
Modified residuei383PhosphoserineBy similarity1
Modified residuei395PhosphothreonineBy similarity1
Modified residuei455PhosphothreonineBy similarity1
Modified residuei456PhosphothreonineBy similarity1
Modified residuei461PhosphothreonineBy similarity1
Modified residuei469PhosphotyrosineBy similarity1
Modified residuei471PhosphoserineBy similarity1
Modified residuei472PhosphothreonineBy similarity1
Modified residuei476PhosphoserineBy similarity1
Modified residuei551PhosphothreonineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ0WVM4.
PRIDEiQ0WVM4.

Expressioni

Gene expression databases

ExpressionAtlasiQ0WVM4. baseline and differential.
GenevisibleiQ0WVM4. AT.

Interactioni

Protein-protein interaction databases

BioGridi2280. 3 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ0WVM4.
SMRiQ0WVM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati99 – 121LRR 1Add BLAST23
Repeati123 – 145LRR 2Add BLAST23
Repeati147 – 167LRR 3Add BLAST21
Repeati171 – 193LRR 4Add BLAST23
Domaini299 – 554Protein kinasePROSITE-ProRule annotationAdd BLAST256

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGB7. Eukaryota.
ENOG410YEGZ. LUCA.
HOGENOMiHOG000116554.
InParanoidiQ0WVM4.
OMAiIGYCASS.
OrthoDBiEOG093604S7.
PhylomeDBiQ0WVM4.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiView protein in InterPro
IPR011009. Kinase-like_dom_sf.
IPR001611. Leu-rich_rpt.
IPR032675. LRR_dom_sf.
IPR013210. LRR_N_plant-typ.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF13855. LRR_8. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS51450. LRR. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0WVM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVMKLITMK IFSVLLLLCF FVTCSLSSEP RNPEVEALIN IKNELHDPHG
60 70 80 90 100
VFKNWDEFSV DPCSWTMISC SSDNLVIGLG APSQSLSGTL SGSIGNLTNL
110 120 130 140 150
RQVSLQNNNI SGKIPPEICS LPKLQTLDLS NNRFSGEIPG SVNQLSNLQY
160 170 180 190 200
LRLNNNSLSG PFPASLSQIP HLSFLDLSYN NLRGPVPKFP ARTFNVAGNP
210 220 230 240 250
LICKNSLPEI CSGSISASPL SVSLRSSSGR RTNILAVALG VSLGFAVSVI
260 270 280 290 300
LSLGFIWYRK KQRRLTMLRI SDKQEEGLLG LGNLRSFTFR ELHVATDGFS
310 320 330 340 350
SKSILGAGGF GNVYRGKFGD GTVVAVKRLK DVNGTSGNSQ FRTELEMISL
360 370 380 390 400
AVHRNLLRLI GYCASSSERL LVYPYMSNGS VASRLKAKPA LDWNTRKKIA
410 420 430 440 450
IGAARGLFYL HEQCDPKIIH RDVKAANILL DEYFEAVVGD FGLAKLLNHE
460 470 480 490 500
DSHVTTAVRG TVGHIAPEYL STGQSSEKTD VFGFGILLLE LITGMRALEF
510 520 530 540 550
GKSVSQKGAM LEWVRKLHKE MKVEELVDRE LGTTYDRIEV GEMLQVALLC
560 570 580 590 600
TQFLPAHRPK MSEVVQMLEG DGLAERWAAS HDHSHFYHAN MSYRTITSTD
610 620 630
GNNQTKHLFG SSGFEDEDDN QALDSFAMEL SGPR
Length:634
Mass (Da):69,694
Last modified:September 5, 2006 - v1
Checksum:iA64A416DBD8AF607
GO

Sequence cautioni

The sequence AAC63680 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005170 Genomic DNA. Translation: AAC63680.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC07507.1.
AK220652 mRNA. Translation: BAD95153.1.
AK226719 mRNA. Translation: BAE98824.1.
FJ708698 mRNA. Translation: ACN59293.1.
PIRiG84630.
RefSeqiNP_179973.2. NM_127957.5.
UniGeneiAt.39223.

Genome annotation databases

EnsemblPlantsiAT2G23950.1; AT2G23950.1; AT2G23950.
GeneIDi816928.
GrameneiAT2G23950.1; AT2G23950.1; AT2G23950.
KEGGiath:AT2G23950.

Similar proteinsi

Entry informationi

Entry nameiY2239_ARATH
AccessioniPrimary (citable) accession number: Q0WVM4
Secondary accession number(s): O82223, Q570Q6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: September 5, 2006
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families