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Q0WUI9

- TPS8_ARATH

UniProt

Q0WUI9 - TPS8_ARATH

Protein

Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8

Gene

TPS8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

    GO - Molecular functioni

    1. transferase activity, transferring glycosyl groups Source: UniProtKB-KW

    GO - Biological processi

    1. trehalose biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciARA:AT1G70290-MONOMER.

    Protein family/group databases

    CAZyiGT20. Glycosyltransferase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 (EC:2.4.1.15)
    Alternative name(s):
    Trehalose-6-phosphate synthase 8
    Short name:
    AtTPS8
    Gene namesi
    Name:TPS8
    Synonyms:TPS2, TPSC
    Ordered Locus Names:At1g70290
    ORF Names:F17O7.18
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G70290.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 856856Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8PRO_0000324829Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei5 – 51PhosphoserineBy similarity
    Modified residuei32 – 321PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ0WUI9.
    PRIDEiQ0WUI9.

    Expressioni

    Tissue specificityi

    Expressed in leaves, roots, stems and flowers.1 Publication

    Gene expression databases

    GenevestigatoriQ0WUI9.

    Interactioni

    Protein-protein interaction databases

    BioGridi28585. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0WUI9.
    SMRiQ0WUI9. Positions 113-541.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni57 – 541485GlycosyltransferaseAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi837 – 8404Poly-Ser

    Sequence similaritiesi

    In the N-terminal section; belongs to the glycosyltransferase 20 family.Curated
    In the C-terminal section; belongs to the trehalose phosphatase family.Curated

    Phylogenomic databases

    eggNOGiCOG0380.
    HOGENOMiHOG000191476.
    InParanoidiQ0WUI9.
    KOiK16055.
    OMAiRACRDHY.
    PhylomeDBiQ0WUI9.

    Family and domain databases

    Gene3Di3.40.50.1000. 2 hits.
    InterProiIPR001830. Glyco_trans_20.
    IPR023214. HAD-like_dom.
    IPR006379. HAD-SF_hydro_IIB.
    IPR003337. Trehalose_PPase.
    [Graphical view]
    PfamiPF00982. Glyco_transf_20. 1 hit.
    PF02358. Trehalose_PPase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01484. HAD-SF-IIB. 1 hit.
    TIGR00685. T6PP. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0WUI9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSRSCANFL DLSSWDLLDF PQTPRTLPRV MTVPGIITDV DGDTTSEVTS    50
    TSGGSRERKI IVANMLPLQS KRDAETGKWC FNWDEDSLQL QLRDGFSSET 100
    EFLYVGSLNV DIETNEQEEV SQKLLEEFNC VATFLSQELQ EMFYLGFCKH 150
    QLWPLFHYML PMFPDHGDRF DRRLWQAYVS ANKIFSDRVM EVINPEDDYV 200
    WIQDYHLMVL PTFLRKRFNR IKLGFFLHSP FPSSEIYRTL PVRDEILRGL 250
    LNCDLIGFHT FDYARHFLSC CSRMLGLDYE SKRGHIGLDY FGRTVYIKIL 300
    PVGVHMGRLE SVLSLDSTAA KTKEIQEQFK GKKLVLGIDD MDIFKGISLK 350
    LIAMEHLFET YWHLKGKVVL VQIVNPARSS GKDVEEAKRE TYETARRINE 400
    RYGTSDYKPI VLIDRLVPRS EKTAYYAAAD CCLVNAVRDG MNLVPYKYIV 450
    CRQGTRSNKA VVDSSPRTST LVVSEFIGCS PSLSGAIRVN PWDVDAVAEA 500
    VNSALKMSET EKQLRHEKHY HYISTHDVGY WAKSFMQDLE RACRDHYSKR 550
    CWGIGFGLGF RVLSLSPSFR KLSVEHIVPV YRKTQRRAIF LDYDGTLVPE 600
    SSIVQDPSNE VVSVLKALCE DPNNTVFIVS GRGRESLSNW LSPCENLGIA 650
    AEHGYFIRWK SKDEWETCYS PTDTEWRSMV EPVMRSYMEA TDGTSIEFKE 700
    SALVWHHQDA DPDFGSCQAK EMLDHLESVL ANEPVVVKRG QHIVEVKPQG 750
    VSKGLAAEKV IREMVERGEP PEMVMCIGDD RSDEDMFESI LSTVTNPELL 800
    VQPEVFACTV GRKPSKAKYF LDDEADVLKL LRGLGDSSSS LKPSSSHTQV 850
    AFESIV 856
    Length:856
    Mass (Da):97,561
    Last modified:September 5, 2006 - v1
    Checksum:i7AA5627BF8307A7C
    GO

    Sequence cautioni

    The sequence AAC18810.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003671 Genomic DNA. Translation: AAC18810.1. Different initiation.
    CP002684 Genomic DNA. Translation: AEE35042.1.
    AK227167 mRNA. Translation: BAE99209.1.
    AF155150 mRNA. Translation: AAO15311.1.
    PIRiT01494.
    RefSeqiNP_177186.2. NM_105697.3.
    UniGeneiAt.27738.

    Genome annotation databases

    EnsemblPlantsiAT1G70290.1; AT1G70290.1; AT1G70290.
    GeneIDi843365.
    KEGGiath:AT1G70290.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003671 Genomic DNA. Translation: AAC18810.1 . Different initiation.
    CP002684 Genomic DNA. Translation: AEE35042.1 .
    AK227167 mRNA. Translation: BAE99209.1 .
    AF155150 mRNA. Translation: AAO15311.1 .
    PIRi T01494.
    RefSeqi NP_177186.2. NM_105697.3.
    UniGenei At.27738.

    3D structure databases

    ProteinModelPortali Q0WUI9.
    SMRi Q0WUI9. Positions 113-541.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 28585. 1 interaction.

    Protein family/group databases

    CAZyi GT20. Glycosyltransferase Family 20.

    Proteomic databases

    PaxDbi Q0WUI9.
    PRIDEi Q0WUI9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G70290.1 ; AT1G70290.1 ; AT1G70290 .
    GeneIDi 843365.
    KEGGi ath:AT1G70290.

    Organism-specific databases

    TAIRi AT1G70290.

    Phylogenomic databases

    eggNOGi COG0380.
    HOGENOMi HOG000191476.
    InParanoidi Q0WUI9.
    KOi K16055.
    OMAi RACRDHY.
    PhylomeDBi Q0WUI9.

    Enzyme and pathway databases

    BioCyci ARA:AT1G70290-MONOMER.

    Gene expression databases

    Genevestigatori Q0WUI9.

    Family and domain databases

    Gene3Di 3.40.50.1000. 2 hits.
    InterProi IPR001830. Glyco_trans_20.
    IPR023214. HAD-like_dom.
    IPR006379. HAD-SF_hydro_IIB.
    IPR003337. Trehalose_PPase.
    [Graphical view ]
    Pfami PF00982. Glyco_transf_20. 1 hit.
    PF02358. Trehalose_PPase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01484. HAD-SF-IIB. 1 hit.
    TIGR00685. T6PP. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues."
      Vogel G., Fiehn O., Jean-Richard-dit-Bressel L., Boller T., Wiemken A., Aeschbacher R.A., Wingler A.
      J. Exp. Bot. 52:1817-1826(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
      Strain: cv. Landsberg erecta.
    2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
      Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
      , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
      Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Isolation and characterization of Arabidopsis trehalose-6-phosphate synthase."
      Kim Y.S., Lee E.J., Kim J.S., Lim D.H., Kim C.K., Chung C.H.
      Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 31-856.
    6. "An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana."
      Leyman B., Van Dijck P., Thevelein J.M.
      Trends Plant Sci. 6:510-513(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiTPS8_ARATH
    AccessioniPrimary (citable) accession number: Q0WUI9
    Secondary accession number(s): O64608
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 18, 2008
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3