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Q0WUI9 (TPS8_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8

EC=2.4.1.15
Alternative name(s):
Trehalose-6-phosphate synthase 8
Short name=AtTPS8
Gene names
Name:TPS8
Synonyms:TPS2, TPSC
Ordered Locus Names:At1g70290
ORF Names:F17O7.18
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length856 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

Tissue specificity

Expressed in leaves, roots, stems and flowers. Ref.1

Sequence similarities

In the N-terminal section; belongs to the glycosyltransferase 20 family.

In the C-terminal section; belongs to the trehalose phosphatase family.

Sequence caution

The sequence AAC18810.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 856856Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8
PRO_0000324829

Regions

Region57 – 541485Glycosyltransferase
Compositional bias837 – 8404Poly-Ser

Amino acid modifications

Modified residue51Phosphoserine By similarity
Modified residue321Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0WUI9 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 7AA5627BF8307A7C

FASTA85697,561
        10         20         30         40         50         60 
MVSRSCANFL DLSSWDLLDF PQTPRTLPRV MTVPGIITDV DGDTTSEVTS TSGGSRERKI 

        70         80         90        100        110        120 
IVANMLPLQS KRDAETGKWC FNWDEDSLQL QLRDGFSSET EFLYVGSLNV DIETNEQEEV 

       130        140        150        160        170        180 
SQKLLEEFNC VATFLSQELQ EMFYLGFCKH QLWPLFHYML PMFPDHGDRF DRRLWQAYVS 

       190        200        210        220        230        240 
ANKIFSDRVM EVINPEDDYV WIQDYHLMVL PTFLRKRFNR IKLGFFLHSP FPSSEIYRTL 

       250        260        270        280        290        300 
PVRDEILRGL LNCDLIGFHT FDYARHFLSC CSRMLGLDYE SKRGHIGLDY FGRTVYIKIL 

       310        320        330        340        350        360 
PVGVHMGRLE SVLSLDSTAA KTKEIQEQFK GKKLVLGIDD MDIFKGISLK LIAMEHLFET 

       370        380        390        400        410        420 
YWHLKGKVVL VQIVNPARSS GKDVEEAKRE TYETARRINE RYGTSDYKPI VLIDRLVPRS 

       430        440        450        460        470        480 
EKTAYYAAAD CCLVNAVRDG MNLVPYKYIV CRQGTRSNKA VVDSSPRTST LVVSEFIGCS 

       490        500        510        520        530        540 
PSLSGAIRVN PWDVDAVAEA VNSALKMSET EKQLRHEKHY HYISTHDVGY WAKSFMQDLE 

       550        560        570        580        590        600 
RACRDHYSKR CWGIGFGLGF RVLSLSPSFR KLSVEHIVPV YRKTQRRAIF LDYDGTLVPE 

       610        620        630        640        650        660 
SSIVQDPSNE VVSVLKALCE DPNNTVFIVS GRGRESLSNW LSPCENLGIA AEHGYFIRWK 

       670        680        690        700        710        720 
SKDEWETCYS PTDTEWRSMV EPVMRSYMEA TDGTSIEFKE SALVWHHQDA DPDFGSCQAK 

       730        740        750        760        770        780 
EMLDHLESVL ANEPVVVKRG QHIVEVKPQG VSKGLAAEKV IREMVERGEP PEMVMCIGDD 

       790        800        810        820        830        840 
RSDEDMFESI LSTVTNPELL VQPEVFACTV GRKPSKAKYF LDDEADVLKL LRGLGDSSSS 

       850 
LKPSSSHTQV AFESIV 

« Hide

References

« Hide 'large scale' references
[1]"Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues."
Vogel G., Fiehn O., Jean-Richard-dit-Bressel L., Boller T., Wiemken A., Aeschbacher R.A., Wingler A.
J. Exp. Bot. 52:1817-1826(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
Strain: cv. Landsberg erecta.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Isolation and characterization of Arabidopsis trehalose-6-phosphate synthase."
Kim Y.S., Lee E.J., Kim J.S., Lim D.H., Kim C.K., Chung C.H.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 31-856.
[6]"An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana."
Leyman B., Van Dijck P., Thevelein J.M.
Trends Plant Sci. 6:510-513(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC003671 Genomic DNA. Translation: AAC18810.1. Different initiation.
CP002684 Genomic DNA. Translation: AEE35042.1.
AK227167 mRNA. Translation: BAE99209.1.
AF155150 mRNA. Translation: AAO15311.1.
PIRT01494.
RefSeqNP_177186.2. NM_105697.3.
UniGeneAt.27738.

3D structure databases

ProteinModelPortalQ0WUI9.
SMRQ0WUI9. Positions 113-541.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid28585. 1 interaction.

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Proteomic databases

PaxDbQ0WUI9.
PRIDEQ0WUI9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G70290.1; AT1G70290.1; AT1G70290.
GeneID843365.
KEGGath:AT1G70290.

Organism-specific databases

TAIRAT1G70290.

Phylogenomic databases

eggNOGCOG0380.
HOGENOMHOG000191476.
InParanoidQ0WUI9.
KOK16055.
OMARACRDHY.
PhylomeDBQ0WUI9.

Enzyme and pathway databases

BioCycARA:AT1G70290-MONOMER.

Gene expression databases

GenevestigatorQ0WUI9.

Family and domain databases

Gene3D3.40.50.1000. 2 hits.
InterProIPR001830. Glyco_trans_20.
IPR023214. HAD-like_dom.
IPR006379. HAD-SF_hydro_IIB.
IPR003337. Trehalose_PPase.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
PF02358. Trehalose_PPase. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR01484. HAD-SF-IIB. 1 hit.
TIGR00685. T6PP. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTPS8_ARATH
AccessionPrimary (citable) accession number: Q0WUI9
Secondary accession number(s): O64608
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names