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Protein

Probable protein phosphatase 2C 73

Gene

PPC6-7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi97Manganese 1By similarity1
Metal bindingi97Manganese 2By similarity1
Metal bindingi98Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi299Manganese 2By similarity1
Metal bindingi345Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • drought recovery Source: TAIR
  • microtubule cytoskeleton organization Source: TAIR
  • negative regulation of growth Source: TAIR
  • protein dephosphorylation Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 73 (EC:3.1.3.16)
Short name:
AtPP2C73
Alternative name(s):
AtPPC6;7
Gene namesi
Name:PPC6-7
Ordered Locus Names:At5g27930
ORF Names:F14I23.90, F15F15.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G27930
TAIRilocus:2143325 AT5G27930

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679931 – 373Probable protein phosphatase 2C 73Add BLAST373

Proteomic databases

PaxDbiQ0WRB2

Expressioni

Gene expression databases

ExpressionAtlasiQ0WRB2 baseline and differential
GenevisibleiQ0WRB2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G27930.1

Structurei

3D structure databases

ProteinModelPortaliQ0WRB2
SMRiQ0WRB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 354PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST294

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi356 – 363Poly-Ser8

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233897
InParanoidiQ0WRB2
OMAiCDAKEAA
OrthoDBiEOG09360GNF
PhylomeDBiQ0WRB2

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0WRB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHFSSMFNG LARSFSIKKV KNNNGNCDAK EAADEMASEA KKKELILKSS
60 70 80 90 100
GYVNVQGSNN LASLFSKRGE KGVNQDCALV WEGFGCQEDM IFCGIFDGHG
110 120 130 140 150
PWGHYVAKQV RNSMPLSLLC NWQKILAQAT LEPELDLEGS NKKISRFDIW
160 170 180 190 200
KQSYLKTCAT VDQELEHHRK IDSYYSGTTA LTIVRQGEVI YVANVGDSRA
210 220 230 240 250
VLAMESDEGS LVAVQLTLDF KPNLPQEKER IIGCKGRVFC LDDEPGVHRV
260 270 280 290 300
WQPDAETPGL AMSRAFGDYC IKEYGLVSVP EVTQRHISTK DHFIILASDG
310 320 330 340 350
IWDVISNQEA IEIVSSTAER PKAAKRLVEQ AVRAWKKKRR GYSMDDMSVV
360 370
CLFLHSSSSS SLSQHHHAMT ILK
Length:373
Mass (Da):41,583
Last modified:September 5, 2006 - v1
Checksum:iA062E30C4169A9F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti56Q → H in BAC43045 (PubMed:11910074).Curated1
Sequence conflicti144I → V in BAC43045 (PubMed:11910074).Curated1
Sequence conflicti242D → N in BAB84697 (Ref. 7) Curated1
Sequence conflicti328V → L in AAM64353 (Ref. 6) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007627 Genomic DNA No translation available.
CP002688 Genomic DNA Translation: AED93745.1
CP002688 Genomic DNA Translation: AED93746.1
AK118436 mRNA Translation: BAC43045.1
AK229967 mRNA Translation: BAF01792.1
AK228402 mRNA Translation: BAF00337.1
BT026463 mRNA Translation: ABH04570.1
AY086281 mRNA Translation: AAM64353.1
AB079668 mRNA Translation: BAB84697.1
RefSeqiNP_568503.1, NM_122675.4
NP_851086.1, NM_180755.2
UniGeneiAt.20140

Genome annotation databases

EnsemblPlantsiAT5G27930.1; AT5G27930.1; AT5G27930
AT5G27930.2; AT5G27930.2; AT5G27930
GeneIDi832860
GrameneiAT5G27930.1; AT5G27930.1; AT5G27930
AT5G27930.2; AT5G27930.2; AT5G27930
KEGGiath:AT5G27930

Similar proteinsi

Entry informationi

Entry nameiP2C73_ARATH
AccessioniPrimary (citable) accession number: Q0WRB2
Secondary accession number(s): Q0WM64
, Q8GX49, Q8LD08, Q8SBC4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health