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Q0WRB2

- P2C73_ARATH

UniProt

Q0WRB2 - P2C73_ARATH

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Protein
Probable protein phosphatase 2C 73
Gene
PPC6-7, At5g27930, F14I23.90, F15F15.3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi97 – 971Manganese 1 By similarity
Metal bindingi97 – 971Manganese 2 By similarity
Metal bindingi98 – 981Manganese 1; via carbonyl oxygen By similarity
Metal bindingi299 – 2991Manganese 2 By similarity
Metal bindingi345 – 3451Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G27930-MONOMER.
ARA:GQT-1455-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 73 (EC:3.1.3.16)
Short name:
AtPP2C73
Alternative name(s):
AtPPC6;7
Gene namesi
Name:PPC6-7
Ordered Locus Names:At5g27930
ORF Names:F14I23.90, F15F15.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G27930.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 373373Probable protein phosphatase 2C 73
PRO_0000367993Add
BLAST

Proteomic databases

PaxDbiQ0WRB2.
PRIDEiQ0WRB2.

Expressioni

Gene expression databases

GenevestigatoriQ0WRB2.

Structurei

3D structure databases

ProteinModelPortaliQ0WRB2.
SMRiQ0WRB2. Positions 83-350.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini175 – 333159PP2C-like
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi356 – 3638Poly-Ser

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ0WRB2.
OMAiCATVDQE.
PhylomeDBiQ0WRB2.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0WRB2-1 [UniParc]FASTAAdd to Basket

« Hide

MGHFSSMFNG LARSFSIKKV KNNNGNCDAK EAADEMASEA KKKELILKSS    50
GYVNVQGSNN LASLFSKRGE KGVNQDCALV WEGFGCQEDM IFCGIFDGHG 100
PWGHYVAKQV RNSMPLSLLC NWQKILAQAT LEPELDLEGS NKKISRFDIW 150
KQSYLKTCAT VDQELEHHRK IDSYYSGTTA LTIVRQGEVI YVANVGDSRA 200
VLAMESDEGS LVAVQLTLDF KPNLPQEKER IIGCKGRVFC LDDEPGVHRV 250
WQPDAETPGL AMSRAFGDYC IKEYGLVSVP EVTQRHISTK DHFIILASDG 300
IWDVISNQEA IEIVSSTAER PKAAKRLVEQ AVRAWKKKRR GYSMDDMSVV 350
CLFLHSSSSS SLSQHHHAMT ILK 373
Length:373
Mass (Da):41,583
Last modified:September 5, 2006 - v1
Checksum:iA062E30C4169A9F8
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti56 – 561Q → H in BAC43045. 1 Publication
Sequence conflicti144 – 1441I → V in BAC43045. 1 Publication
Sequence conflicti242 – 2421D → N in BAB84697. 1 Publication
Sequence conflicti328 – 3281V → L in AAM64353. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC007627 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED93745.1.
CP002688 Genomic DNA. Translation: AED93746.1.
AK118436 mRNA. Translation: BAC43045.1.
AK229967 mRNA. Translation: BAF01792.1.
AK228402 mRNA. Translation: BAF00337.1.
BT026463 mRNA. Translation: ABH04570.1.
AY086281 mRNA. Translation: AAM64353.1.
AB079668 mRNA. Translation: BAB84697.1.
RefSeqiNP_568503.1. NM_122675.3.
NP_851086.1. NM_180755.1.
UniGeneiAt.20140.

Genome annotation databases

EnsemblPlantsiAT5G27930.1; AT5G27930.1; AT5G27930.
AT5G27930.2; AT5G27930.2; AT5G27930.
GeneIDi832860.
KEGGiath:AT5G27930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC007627 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED93745.1 .
CP002688 Genomic DNA. Translation: AED93746.1 .
AK118436 mRNA. Translation: BAC43045.1 .
AK229967 mRNA. Translation: BAF01792.1 .
AK228402 mRNA. Translation: BAF00337.1 .
BT026463 mRNA. Translation: ABH04570.1 .
AY086281 mRNA. Translation: AAM64353.1 .
AB079668 mRNA. Translation: BAB84697.1 .
RefSeqi NP_568503.1. NM_122675.3.
NP_851086.1. NM_180755.1.
UniGenei At.20140.

3D structure databases

ProteinModelPortali Q0WRB2.
SMRi Q0WRB2. Positions 83-350.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q0WRB2.
PRIDEi Q0WRB2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G27930.1 ; AT5G27930.1 ; AT5G27930 .
AT5G27930.2 ; AT5G27930.2 ; AT5G27930 .
GeneIDi 832860.
KEGGi ath:AT5G27930.

Organism-specific databases

TAIRi AT5G27930.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233897.
InParanoidi Q0WRB2.
OMAi CATVDQE.
PhylomeDBi Q0WRB2.

Enzyme and pathway databases

BioCyci ARA:AT5G27930-MONOMER.
ARA:GQT-1455-MONOMER.

Gene expression databases

Genevestigatori Q0WRB2.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Arabidopsis ORF Clones."
    Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  7. "Substrate specificity of type 2C protein phosphatases (PP2C) in Arabidopsis thaliana."
    Izumi S., Yamada M., Ohsato H., Miyazaki S., Bohnert H.J., Fukuhara T.
    Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 37-373.
  8. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C73_ARATH
AccessioniPrimary (citable) accession number: Q0WRB2
Secondary accession number(s): Q0WM64
, Q8GX49, Q8LD08, Q8SBC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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