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Q0WRB2 (P2C73_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 73
Short name=AtPP2C73
EC=3.1.3.16
Alternative name(s):
AtPPC6;7
Gene names
Name:PPC6-7
Ordered Locus Names:At5g27930
ORF Names:F14I23.90, F15F15.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmetabolic process

Inferred from electronic annotation. Source: GOC

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 373373Probable protein phosphatase 2C 73
PRO_0000367993

Regions

Domain175 – 333159PP2C-like
Compositional bias356 – 3638Poly-Ser

Sites

Metal binding971Manganese 1 By similarity
Metal binding971Manganese 2 By similarity
Metal binding981Manganese 1; via carbonyl oxygen By similarity
Metal binding2991Manganese 2 By similarity
Metal binding3451Manganese 2 By similarity

Experimental info

Sequence conflict561Q → H in BAC43045. Ref.3
Sequence conflict1441I → V in BAC43045. Ref.3
Sequence conflict2421D → N in BAB84697. Ref.7
Sequence conflict3281V → L in AAM64353. Ref.6

Sequences

Sequence LengthMass (Da)Tools
Q0WRB2 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: A062E30C4169A9F8

FASTA37341,583
        10         20         30         40         50         60 
MGHFSSMFNG LARSFSIKKV KNNNGNCDAK EAADEMASEA KKKELILKSS GYVNVQGSNN 

        70         80         90        100        110        120 
LASLFSKRGE KGVNQDCALV WEGFGCQEDM IFCGIFDGHG PWGHYVAKQV RNSMPLSLLC 

       130        140        150        160        170        180 
NWQKILAQAT LEPELDLEGS NKKISRFDIW KQSYLKTCAT VDQELEHHRK IDSYYSGTTA 

       190        200        210        220        230        240 
LTIVRQGEVI YVANVGDSRA VLAMESDEGS LVAVQLTLDF KPNLPQEKER IIGCKGRVFC 

       250        260        270        280        290        300 
LDDEPGVHRV WQPDAETPGL AMSRAFGDYC IKEYGLVSVP EVTQRHISTK DHFIILASDG 

       310        320        330        340        350        360 
IWDVISNQEA IEIVSSTAER PKAAKRLVEQ AVRAWKKKRR GYSMDDMSVV CLFLHSSSSS 

       370 
SLSQHHHAMT ILK

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Arabidopsis ORF Clones."
Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[7]"Substrate specificity of type 2C protein phosphatases (PP2C) in Arabidopsis thaliana."
Izumi S., Yamada M., Ohsato H., Miyazaki S., Bohnert H.J., Fukuhara T.
Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 37-373.
[8]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC007627 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED93745.1.
CP002688 Genomic DNA. Translation: AED93746.1.
AK118436 mRNA. Translation: BAC43045.1.
AK229967 mRNA. Translation: BAF01792.1.
AK228402 mRNA. Translation: BAF00337.1.
BT026463 mRNA. Translation: ABH04570.1.
AY086281 mRNA. Translation: AAM64353.1.
AB079668 mRNA. Translation: BAB84697.1.
IPIIPI00535939.
RefSeqNP_568503.1. NM_122675.3.
NP_851086.1. NM_180755.1.
UniGeneAt.20140.

3D structure databases

ProteinModelPortalQ0WRB2.
SMRQ0WRB2. Positions 83-350.
ModBaseSearch...

Proteomic databases

PaxDbQ0WRB2.
PRIDEQ0WRB2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G27930.1; AT5G27930.1; AT5G27930.
AT5G27930.2; AT5G27930.2; AT5G27930.
GeneID832860.
KEGGath:AT5G27930.

Organism-specific databases

TAIRAt5g27930.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233897.
InParanoidQ0WRB2.
OMASSMFNGL.
PhylomeDBQ0WRB2.
ProtClustDBCLSN2684495.

Gene expression databases

GenevestigatorQ0WRB2.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. PP2C-related. 1 hit.
PROSITEPS01032. PP2C. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C73_ARATH
AccessionPrimary (citable) accession number: Q0WRB2
Secondary accession number(s): Q0WM64 expand/collapse secondary AC list , Q8GX49, Q8LD08, Q8SBC4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents