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Protein

Pentatricopeptide repeat-containing protein At1g59720, chloroplastic/mitochondrial

Gene

PCMP-H51

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in multiple sites RNA editing events in chloroplasts. Involved in the editing of the site 2 of ndhB (ndhB-2) and site 3 of ndhD (ndhD-3) transcripts, which are two plastid-encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH) complex. Required for the activity of the NDH complex of the photosynthetic electron transport chain.1 Publication

Miscellaneous

The DYW motif is dispensable for editing activity in vivo.1 Publication

GO - Molecular functioni

  • endonuclease activity Source: TAIR
  • RNA binding Source: GO_Central
  • zinc ion binding Source: InterPro

GO - Biological processi

  • chloroplast RNA modification Source: GO_Central
  • chloroplast RNA processing Source: GO_Central
  • mRNA modification Source: TAIR
  • mRNA processing Source: UniProtKB-KW

Keywordsi

Biological processmRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Pentatricopeptide repeat-containing protein At1g59720, chloroplastic/mitochondrialCurated
Alternative name(s):
Protein CHLORORESPIRATORY REDUCTION 281 Publication
Gene namesi
Name:PCMP-H51
Synonyms:CRR281 Publication
Ordered Locus Names:At1g59720
ORF Names:F23H11.3, T30E16.32
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G59720
TAIRilocus:2025946 AT1G59720

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Mitochondrion, Plastid

Pathology & Biotechi

Disruption phenotypei

Impaired chloroplastic NAD(P)H dehydrogenase (NDH) activity.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 40Chloroplast and mitochondrionAdd BLAST40
ChainiPRO_000034282641 – 638Pentatricopeptide repeat-containing protein At1g59720, chloroplastic/mitochondrialSequence analysisAdd BLAST598

Proteomic databases

PaxDbiQ0WQW5
PRIDEiQ0WQW5

Expressioni

Gene expression databases

ExpressionAtlasiQ0WQW5 baseline and differential
GenevisibleiQ0WQW5 AT

Interactioni

Subunit structurei

Interacts with ORRM1 (PubMed:23487777). Interacts with VAR3/OZ1 (PubMed:25768119).2 Publications

Protein-protein interaction databases

BioGridi27488, 1 interactor
STRINGi3702.AT1G59720.1

Structurei

3D structure databases

ProteinModelPortaliQ0WQW5
SMRiQ0WQW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati82 – 112PPR 1Add BLAST31
Repeati113 – 148PPR 2Add BLAST36
Repeati150 – 184PPR 3Add BLAST35
Repeati185 – 215PPR 4Add BLAST31
Repeati216 – 246PPR 5Add BLAST31
Repeati250 – 280PPR 6Add BLAST31
Repeati288 – 318PPR 7Add BLAST31
Repeati319 – 353PPR 8Add BLAST35
Repeati356 – 390PPR 9Add BLAST35
Repeati392 – 422PPR 10Add BLAST31

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni427 – 510Type E motifAdd BLAST84
Regioni511 – 541Type E(+) motifAdd BLAST31
Regioni542 – 638Type DYW motifAdd BLAST97

Sequence similaritiesi

Belongs to the PPR family. PCMP-H subfamily.Curated

Keywords - Domaini

Repeat, Transit peptide

Phylogenomic databases

eggNOGiKOG4197 Eukaryota
ENOG410Z7Z7 LUCA
HOGENOMiHOG000237569
InParanoidiQ0WQW5
OMAiSCGCLDL
OrthoDBiEOG093604V6
PhylomeDBiQ0WQW5

Family and domain databases

Gene3Di1.25.40.10, 4 hits
InterProiView protein in InterPro
IPR032867 DYW_dom
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 1 hit
PF13041 PPR_2, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
TIGRFAMsiTIGR00756 PPR, 4 hits
PROSITEiView protein in PROSITE
PS51375 PPR, 10 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0WQW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVRSIIVSP PTTITYYHPM SIGLLVHPLS PHIPPASSPS ASTAGNHHQR
60 70 80 90 100
IFSLAETCSD MSQLKQLHAF TLRTTYPEEP ATLFLYGKIL QLSSSFSDVN
110 120 130 140 150
YAFRVFDSIE NHSSFMWNTL IRACAHDVSR KEEAFMLYRK MLERGESSPD
160 170 180 190 200
KHTFPFVLKA CAYIFGFSEG KQVHCQIVKH GFGGDVYVNN GLIHLYGSCG
210 220 230 240 250
CLDLARKVFD EMPERSLVSW NSMIDALVRF GEYDSALQLF REMQRSFEPD
260 270 280 290 300
GYTMQSVLSA CAGLGSLSLG TWAHAFLLRK CDVDVAMDVL VKNSLIEMYC
310 320 330 340 350
KCGSLRMAEQ VFQGMQKRDL ASWNAMILGF ATHGRAEEAM NFFDRMVDKR
360 370 380 390 400
ENVRPNSVTF VGLLIACNHR GFVNKGRQYF DMMVRDYCIE PALEHYGCIV
410 420 430 440 450
DLIARAGYIT EAIDMVMSMP MKPDAVIWRS LLDACCKKGA SVELSEEIAR
460 470 480 490 500
NIIGTKEDNE SSNGNCSGAY VLLSRVYASA SRWNDVGIVR KLMSEHGIRK
510 520 530 540 550
EPGCSSIEIN GISHEFFAGD TSHPQTKQIY QQLKVIDDRL RSIGYLPDRS
560 570 580 590 600
QAPLVDATND GSKEYSLRLH SERLAIAFGL INLPPQTPIR IFKNLRVCND
610 620 630
CHEVTKLISK VFNTEIIVRD RVRFHHFKDG SCSCLDYW
Length:638
Mass (Da):71,960
Last modified:July 1, 2008 - v2
Checksum:iB868192817B41756
GO

Sequence cautioni

The sequence AAD39314 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAF79766 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007258 Genomic DNA Translation: AAD39314.1 Sequence problems.
AC009317 Genomic DNA Translation: AAF79766.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE33607.1
AK228565 mRNA Translation: BAF00484.1
PIRiH96620
RefSeqiNP_176180.1, NM_104664.2
UniGeneiAt.11368
At.66916

Genome annotation databases

EnsemblPlantsiAT1G59720.1; AT1G59720.1; AT1G59720
GeneIDi842263
GrameneiAT1G59720.1; AT1G59720.1; AT1G59720
KEGGiath:AT1G59720

Similar proteinsi

Entry informationi

Entry nameiPPR85_ARATH
AccessioniPrimary (citable) accession number: Q0WQW5
Secondary accession number(s): Q9LQ42, Q9XIF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 23, 2018
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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