Q0WPY0 (TLP6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tubby-like F-box protein 6
Short name=AtTLP6

Gene names

Name:	TULP6
Ordered Locus Names:	At1g47270
ORF Names:	F8G22.1

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Ubiquitous, with higher levels in flowers. Ref.4
Sequence similarities	Belongs to the TUB family. Contains 1 F-box domain.
Sequence caution	The sequence AAG52638.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	pollen development Inferred from mutant phenotype PubMed 22101548. Source: TAIR
Molecular_function	sequence-specific DNA binding transcription factor activity Inferred from sequence or structural similarity PubMed 11118137. Source: TAIR
Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q0WPY0-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 413	413	Tubby-like F-box protein 6		PRO_0000272234
Regions
	Domain	67 – 122	56	F-box

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 56DC573373C1F11A	FASTA	413	46,065
	10 20 30 40 50 60 MDLSLLLPKR SWEISGGADK ISRVAMSLKN IVKNKYKAIG RRGRSHIAPE GSSVSSSLST 70 80 90 100 110 120 NEGLNQSIWV DLPPELLLDI IQRIESEQSL WPGRRDVVAC ASVCKSWREM TKEVVKVPEL 130 140 150 160 170 180 SGLITFPISL RQPGPRDAPI QCFIKRERAT GIYRLYLGLS PALSGDKSKL LLSAKRVRRA 190 200 210 220 230 240 TGAEFVVSLS GNDFSRSSSN YIGKLRSNFL GTKFTVYENQ PPPFNRKLPP SMQVSPWVSS 250 260 270 280 290 300 SSSSYNIASI LYELNVLRTR GPRRMQCIMH SIPISAIQEG GKIQSPTEFT NQGKKKKKPL 310 320 330 340 350 360 MDFCSGNLGG ESVIKEPLIL KNKSPRWHEQ LQCWCLNFKG RVTVASVKNF QLVAAAAEAG 370 380 390 400 410 KNMNIPEEEQ DRVILQFGKI GKDIFTMDYR YPISAFQAFA ICLSSFDTKP VCE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Molecular analyses of the Arabidopsis TUBBY-like protein gene family." Lai C.-P., Lee C.-L., Chen P.-H., Wu S.-H., Yang C.-C., Shaw J.-F. Plant Physiol. 134:1586-1597(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 26-413, TISSUE SPECIFICITY, GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC079677 Genomic DNA. Translation: AAG52638.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE32146.1. AK228930 mRNA. Translation: BAF00819.1. AF487268 mRNA. Translation: AAQ06241.1.
IPI	IPI00536729.
PIR	E96513.
RefSeq	NP_175160.2. NM_103621.2.
UniGene	At.18294.
3D structure databases
ProteinModelPortal	Q0WPY0.
SMR	Q0WPY0. Positions 132-407.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G47270.1; AT1G47270.1; AT1G47270.
GeneID	841130.
KEGG	ath:AT1G47270.
Organism-specific databases
TAIR	At1g47270.
Phylogenomic databases
eggNOG	NOG286778.
HOGENOM	HOG000238161.
InParanoid	Q0WPY0.
OMA	NIASILY.
PhylomeDB	Q0WPY0.
ProtClustDB	CLSN2918335.
Gene expression databases
ArrayExpress	Q0WPY0.
Genevestigator	Q0WPY0.
Family and domain databases
Gene3D	3.20.90.10. 1 hit.
InterPro	IPR001810. F-box_dom_cyclin-like. IPR000007. Tubby_C. IPR025659. Tubby_C-like. IPR018066. Tubby_C_CS. [Graphical view]
Pfam	PF01167. Tub. 1 hit. [Graphical view]
PRINTS	PR01573. SUPERTUBBY.
SUPFAM	SSF81383. F-box_dom_Skp2-like. 1 hit. SSF54518. Tubby_C. 1 hit.
PROSITE	PS50181. FBOX. False negative. PS01200. TUB_1. 1 hit. PS01201. TUB_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TLP6_ARATH

Accession

Primary (citable) accession number: Q0WPY0
Secondary accession number(s): Q9C6B4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	September 5, 2006
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program