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Q0WJK7

- Q0WJK7_YERPE

UniProt

Q0WJK7 - Q0WJK7_YERPE

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Protein
Submitted name:

Bifunctional aspartokinase/homoserine dehydrogenase I

Gene

thrA

Organism
Yersinia pestis
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. aspartate kinase activity Source: UniProtKB-EC
  3. homoserine dehydrogenase activity Source: InterPro
  4. NADP binding Source: InterPro

GO - Biological processi

  1. aspartate family amino acid biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciYPES214092:GKDD-454-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional aspartokinase/homoserine dehydrogenase IImported (EC:2.7.2.4Imported)
Gene namesi
Name:thrAImported
Ordered Locus Names:YPO0459Imported
OrganismiYersinia pestisImported
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi214092.YPO0459.

Structurei

3D structure databases

ProteinModelPortaliQ0WJK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000271593.
KOiK12524.
OMAiYIFGMLD.
OrthoDBiEOG6M0T34.

Family and domain databases

Gene3Di3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR027795. GATS-like_ACT_dom.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 2 hits.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000727. ThrA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
PROSITEiPS51671. ACT. 2 hits.
PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0WJK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRVLKFGGTS VANAERFMRV ADIIESNARQ GQVATVLSAP AKITNHLVAM
60 70 80 90 100
IDKMVAGQDI SPNISDAERI FAELLRGLAD TQPGFDYDRL KALVGHEFAQ
110 120 130 140 150
LKHLLHGISL LGQCPDSINA SIICRGEKLS IAIMEALFQA KGYHVTVINP
160 170 180 190 200
VEKLLAQGHY LESTVDITES TRRIGASGIP SDHIILMAGF TAGNDKGELV
210 220 230 240 250
VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRTV PDARLLKSMS
260 270 280 290 300
YQEAMELSYF GAKVLHPRTI APIARFQIPC LIKNTSNPQA PGTLIGGESI
310 320 330 340 350
DEDSPVKGIT NLNNMAMINV SGPGMKGMVG MAARVFAVMS RSGISVVLIT
360 370 380 390 400
QSSSEYSISF CVPQGELLRA RRALEDEFYL ELKDGVLDPL DVMEHLAIIS
410 420 430 440 450
VVGDGMRTLR GISARFFSAL ARANINIIAI AQGSSERSIS VVVNNDAVTT
460 470 480 490 500
GVRVCHQMLF NTDQVIEVFV IGVGGVGGAL IEQIYRQQPW LKQRHIDLRV
510 520 530 540 550
CGIANSKAML TNVHGIALDN WRQELAEVQE PFNLSRLIRL VKEYHLLNPV
560 570 580 590 600
IVDCTSSQAV ADQYADFLTD GFHVVTPNKK ANTSSMNYYR QMRAAATKSC
610 620 630 640 650
RKFLYDTNVG AGLPVIENLQ NLLNAGDELM RFTGILSGSL SFIFGKLDEG
660 670 680 690 700
MSLSEATRQA KALGYTEPDP RDDLSGMDVA RKLLILAREA GYKLELADIE
710 720 730 740 750
VESVLPASFD ASGDVDTFLA RLPSLDAEFT RLVANAAEQG KVLRYVGVIE
760 770 780 790 800
DGRCKVRMEA VDGNDPLYKV KNGENALAFY TRYYQPIPLV LRGYGAGNDV
810
TAAGVFADLL RTLSWKLGV
Length:819
Mass (Da):89,110
Last modified:September 5, 2006 - v1
Checksum:iE8249C805C945285
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL19138.1.
PIRiAH0056.
RefSeqiYP_002345531.1. NC_003143.1.

Genome annotation databases

GeneIDi1173303.
KEGGiype:YPO0459.
PATRICi18590007. VBIYerPes7843_0741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL19138.1 .
PIRi AH0056.
RefSeqi YP_002345531.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q0WJK7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO0459.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1173303.
KEGGi ype:YPO0459.
PATRICi 18590007. VBIYerPes7843_0741.

Phylogenomic databases

HOGENOMi HOG000271593.
KOi K12524.
OMAi YIFGMLD.
OrthoDBi EOG6M0T34.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-454-MONOMER.

Family and domain databases

Gene3Di 3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProi IPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR027795. GATS-like_ACT_dom.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 2 hits.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000727. ThrA. 1 hit.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00657. asp_kinases. 1 hit.
PROSITEi PS51671. ACT. 2 hits.
PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar OrientalisImported.

Entry informationi

Entry nameiQ0WJK7_YERPE
AccessioniPrimary (citable) accession number: Q0WJK7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 1, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3