Bifunctional aspartokinase/homoserine dehydrogenase I

Preferred order of sections

Names and origin

Protein names

Submitted name:
Bifunctional aspartokinase/homoserine dehydrogenase I EMBL CAL19138.1
EC=2.7.2.4 EMBL CAL19138.1

Gene names

Name:	thrA EMBL CAL19138.1
Ordered Locus Names:	YPO0459 EMBL CAL19138.1

Organism

Yersinia pestis [Reference proteome] [HAMAP]

Taxonomic identifier

632 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	819 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Kinase EMBL CAL19138.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	aspartate family amino acid biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro aspartate kinase activity Inferred from electronic annotation. Source: EC homoserine dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q0WJK7 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: E8249C805C945285
Show »

FASTA

819

89,110

        10         20         30         40         50         60 
MRVLKFGGTS VANAERFMRV ADIIESNARQ GQVATVLSAP AKITNHLVAM IDKMVAGQDI 

        70         80         90        100        110        120 
SPNISDAERI FAELLRGLAD TQPGFDYDRL KALVGHEFAQ LKHLLHGISL LGQCPDSINA 

       130        140        150        160        170        180 
SIICRGEKLS IAIMEALFQA KGYHVTVINP VEKLLAQGHY LESTVDITES TRRIGASGIP 

       190        200        210        220        230        240 
SDHIILMAGF TAGNDKGELV VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRTV 

       250        260        270        280        290        300 
PDARLLKSMS YQEAMELSYF GAKVLHPRTI APIARFQIPC LIKNTSNPQA PGTLIGGESI 

       310        320        330        340        350        360 
DEDSPVKGIT NLNNMAMINV SGPGMKGMVG MAARVFAVMS RSGISVVLIT QSSSEYSISF 

       370        380        390        400        410        420 
CVPQGELLRA RRALEDEFYL ELKDGVLDPL DVMEHLAIIS VVGDGMRTLR GISARFFSAL 

       430        440        450        460        470        480 
ARANINIIAI AQGSSERSIS VVVNNDAVTT GVRVCHQMLF NTDQVIEVFV IGVGGVGGAL 

       490        500        510        520        530        540 
IEQIYRQQPW LKQRHIDLRV CGIANSKAML TNVHGIALDN WRQELAEVQE PFNLSRLIRL 

       550        560        570        580        590        600 
VKEYHLLNPV IVDCTSSQAV ADQYADFLTD GFHVVTPNKK ANTSSMNYYR QMRAAATKSC 

       610        620        630        640        650        660 
RKFLYDTNVG AGLPVIENLQ NLLNAGDELM RFTGILSGSL SFIFGKLDEG MSLSEATRQA 

       670        680        690        700        710        720 
KALGYTEPDP RDDLSGMDVA RKLLILAREA GYKLELADIE VESVLPASFD ASGDVDTFLA 

       730        740        750        760        770        780 
RLPSLDAEFT RLVANAAEQG KVLRYVGVIE DGRCKVRMEA VDGNDPLYKV KNGENALAFY 

       790        800        810 
TRYYQPIPLV LRGYGAGNDV TAAGVFADLL RTLSWKLGV

« Hide

References

[1]

"Genome sequence of Yersinia pestis, the causative agent of plague."
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M.

Barrell B.G.
Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CO-92 / Biovar Orientalis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL590842 Genomic DNA. Translation: CAL19138.1.
PIR	AH0056.
RefSeq	YP_002345531.1. NC_003143.1.
3D structure databases
ProteinModelPortal	Q0WJK7.
ModBase	Search...
Protein-protein interaction databases
STRING	214092.YPO0459.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1173303.
KEGG	ype:YPO0459.
PATRIC	18590007. VBIYerPes7843_0741.
Phylogenomic databases
HOGENOM	HOG000271593.
KO	K12524.
OMA	IFISQAS.
ProtClustDB	PRK09436.
Enzyme and pathway databases
BioCyc	YPES214092:GKDD-454-MONOMER.
Family and domain databases
Gene3D	3.40.1160.10. 2 hits. 3.40.50.720. 1 hit.
InterPro	IPR001048. Asp/Glu/Uridylate_kinase. IPR005106. Asp/hSer_DH_NAD-bd. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. IPR011147. Bifunc_aspartokin/hSer_DH. IPR001342. HDH_cat. IPR019811. HDH_CS. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00696. AA_kinase. 1 hit. PF00742. Homoserine_dh. 1 hit. PF03447. NAD_binding_3. 1 hit. [Graphical view]
PIRSF	PIRSF000727. ThrA. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00657. asp_kinases. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. PS01042. HOMOSER_DHGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0WJK7_YERPE

Accession

Primary (citable) accession number: Q0WJK7

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	May 29, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information