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Protein

50S ribosomal protein L3 glutamine methyltransferase

Gene

prmB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + [ribosomal protein L3]-L-glutamine = S-adenosyl-L-homocysteine + [ribosomal protein L3]-N(5)-methyl-L-glutamine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2719-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3 glutamine methyltransferaseUniRule annotation (EC:2.1.1.298UniRule annotation)
Short name:
L3 MTaseUniRule annotation
Alternative name(s):
N5-glutamine methyltransferase PrmBUniRule annotation
Gene namesi
Name:prmBUniRule annotation
Ordered Locus Names:YPO2750, y1584, YP_2413
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 31031050S ribosomal protein L3 glutamine methyltransferasePRO_0000414185Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiQ0WDE1. 4 interactions.
STRINGi187410.y1584.

Structurei

3D structure databases

ProteinModelPortaliQ0WDE1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C76. Bacteria.
COG2890. LUCA.
HOGENOMiHOG000076275.
KOiK07320.
OMAiVLVCEVG.
OrthoDBiEOG68Q0SZ.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_02125. L3_methyltr_PrmB.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR004556. Modification_methylase_HemK.
IPR017127. Ribosome_L3_Gln-N5_MeTrfase.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037167. Mtase_YfcB_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00536. hemK_fam. 1 hit.
TIGR03533. L3_gln_methyl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0WDE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKIFVDEAV NELHTIQDML RWTVSRFNAA NIFYGHGTDN PWDEAVQLVF
60 70 80 90 100
PSLFLPLDIP EDIRSSRLTS SERHRIVERV IRRVNERIPV AYLTNKAWFC
110 120 130 140 150
GMEYYVDERV LVPRSPIGEL IENRFDGLIH HQPNHILDMC TGSGCIAIAC
160 170 180 190 200
AYAFPDAEVD AVDISNDVLA VTEHNIQQHG MEHQVTPIRS DLFRDLPPIK
210 220 230 240 250
YDLIVTNPPY VDAEDMADLP QEFRFEPELG LAAGSDGLKL ARRILACAPD
260 270 280 290 300
FLQDDGVLIC EVGNSMVHLM DQYPDVPFTW LEFEKGGDGV FMLTKQQLID
310
CAAHFSMYRD
Length:310
Mass (Da):35,296
Last modified:September 5, 2006 - v1
Checksum:iA2CC87125E3F0483
GO

Sequence cautioni

The sequence AAM85153.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAS62618.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL21369.1.
AE009952 Genomic DNA. Translation: AAM85153.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62618.1. Different initiation.
PIRiAF0335.
RefSeqiWP_002209710.1. NZ_LIXY01000015.1.
YP_002347697.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM85153; AAM85153; y1584.
AAS62618; AAS62618; YP_2413.
GeneIDi1175581.
KEGGiype:YPO2750.
ypj:CH55_10.
ypk:y1584.
ypl:CH46_2351.
ypm:YP_2413.
ypv:BZ15_775.
ypw:CH59_3637.
PATRICi18595308. VBIYerPes7843_3357.
18623676. VBIYerPes99487_2770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL21369.1.
AE009952 Genomic DNA. Translation: AAM85153.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62618.1. Different initiation.
PIRiAF0335.
RefSeqiWP_002209710.1. NZ_LIXY01000015.1.
YP_002347697.1. NC_003143.1.

3D structure databases

ProteinModelPortaliQ0WDE1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ0WDE1. 4 interactions.
STRINGi187410.y1584.

Protocols and materials databases

DNASUi1146531.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM85153; AAM85153; y1584.
AAS62618; AAS62618; YP_2413.
GeneIDi1175581.
KEGGiype:YPO2750.
ypj:CH55_10.
ypk:y1584.
ypl:CH46_2351.
ypm:YP_2413.
ypv:BZ15_775.
ypw:CH59_3637.
PATRICi18595308. VBIYerPes7843_3357.
18623676. VBIYerPes99487_2770.

Phylogenomic databases

eggNOGiENOG4105C76. Bacteria.
COG2890. LUCA.
HOGENOMiHOG000076275.
KOiK07320.
OMAiVLVCEVG.
OrthoDBiEOG68Q0SZ.

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2719-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_02125. L3_methyltr_PrmB.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR004556. Modification_methylase_HemK.
IPR017127. Ribosome_L3_Gln-N5_MeTrfase.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037167. Mtase_YfcB_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00536. hemK_fam. 1 hit.
TIGR03533. L3_gln_methyl. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiPRMB_YERPE
AccessioniPrimary (citable) accession number: Q0WDE1
Secondary accession number(s): Q74SY9, Q8D0U7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: September 5, 2006
Last modified: May 11, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.