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Protein

50S ribosomal protein L3 glutamine methyltransferase

Gene

prmB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + [ribosomal protein L3]-L-glutamine = S-adenosyl-L-homocysteine + [ribosomal protein L3]-N5-methyl-L-glutamine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3 glutamine methyltransferaseUniRule annotation (EC:2.1.1.298UniRule annotation)
Short name:
L3 MTaseUniRule annotation
Alternative name(s):
N5-glutamine methyltransferase PrmBUniRule annotation
Gene namesi
Name:prmBUniRule annotation
Ordered Locus Names:YPO2750, y1584, YP_2413
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004141851 – 31050S ribosomal protein L3 glutamine methyltransferaseAdd BLAST310

Proteomic databases

PaxDbiQ0WDE1

Interactioni

Protein-protein interaction databases

IntActiQ0WDE1, 4 interactors
STRINGi187410.y1584

Structurei

3D structure databases

ProteinModelPortaliQ0WDE1
SMRiQ0WDE1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C76 Bacteria
COG2890 LUCA
HOGENOMiHOG000076275
KOiK07320
OMAiVLVCEVG

Family and domain databases

HAMAPiMF_02125 L3_methyltr_PrmB, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR004556 Modification_methylase_HemK
IPR017127 Ribosome_L3_Gln-N5_MeTrfase
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PIRSFiPIRSF037167 Mtase_YfcB_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00536 hemK_fam, 1 hit
TIGR03533 L3_gln_methyl, 1 hit

Sequencei

Sequence statusi: Complete.

Q0WDE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKIFVDEAV NELHTIQDML RWTVSRFNAA NIFYGHGTDN PWDEAVQLVF
60 70 80 90 100
PSLFLPLDIP EDIRSSRLTS SERHRIVERV IRRVNERIPV AYLTNKAWFC
110 120 130 140 150
GMEYYVDERV LVPRSPIGEL IENRFDGLIH HQPNHILDMC TGSGCIAIAC
160 170 180 190 200
AYAFPDAEVD AVDISNDVLA VTEHNIQQHG MEHQVTPIRS DLFRDLPPIK
210 220 230 240 250
YDLIVTNPPY VDAEDMADLP QEFRFEPELG LAAGSDGLKL ARRILACAPD
260 270 280 290 300
FLQDDGVLIC EVGNSMVHLM DQYPDVPFTW LEFEKGGDGV FMLTKQQLID
310
CAAHFSMYRD
Length:310
Mass (Da):35,296
Last modified:September 5, 2006 - v1
Checksum:iA2CC87125E3F0483
GO

Sequence cautioni

The sequence AAM85153 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAS62618 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL21369.1
AE009952 Genomic DNA Translation: AAM85153.1 Different initiation.
AE017042 Genomic DNA Translation: AAS62618.1 Different initiation.
PIRiAF0335
RefSeqiWP_002209710.1, NZ_PDBR01000017.1
YP_002347697.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM85153; AAM85153; y1584
AAS62618; AAS62618; YP_2413
GeneIDi1175581
KEGGiype:YPO2750
ypk:y1584
ypm:YP_2413
PATRICifig|1028802.3.peg.1708

Similar proteinsi

Entry informationi

Entry nameiPRMB_YERPE
AccessioniPrimary (citable) accession number: Q0WDE1
Secondary accession number(s): Q74SY9, Q8D0U7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health