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Reviewed, UniProtKB/Swiss-Prot Q0W8U9 (MCH_UNCMA)

Last modified June 16, 2009. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Methenyltetrahydromethanopterin cyclohydrolase
    EC=3.5.4.27
Alternative name(s):
    Methenyl-H4MPT cyclohydrolase
Gene names
Name: mch
Ordered Locus Names: UNCMA_29790
ORF Names: LRC191
OrganismUncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP]
Taxonomic identifier351160 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaenvironmental samples

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the reversible interconversion of 5-formyl-H4MPT to methenyl-H4MPT+ By similarity.

Catalytic activity

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = 5-formyl-5,6,7,8-tetrahydromethanopterin. HAMAP MF_00486

Pathway

One-carbon metabolism; methanogenesis from carbone dioxide; 5,10-methenyl-H(4)MPT from CO(2): step 3/3. HAMAP MF_00486

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the MCH family.

Ontologies

Keywords
   Biological processMethanogenesis
One-carbon metabolism
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processmethanogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethenyltetrahydromethanopterin cyclohydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Methenyltetrahydromethanopterin cyclohydrolase HAMAP MF_00486
PRO_1000014406

Sequences

Sequence LengthMass (Da)Tools
Q0W8U9-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 3659B4B755F87D28

FASTA31834,455
        10         20         30         40         50         60 
MISINEISYS IVEEMLDFAE DYRIEPHTLA NDSVVIDCGV KAKAGYEAGL LFTQVCMGGL 

        70         80         90        100        110        120 
AQTSLTHKKL KHEVFYPFIE VSTDFPAIAC LAAQKAGWRI SQDGYFAMGS GPARALALKP 

       130        140        150        160        170        180 
KHTYEVIEYE DDYDFAVIAL EADKLPNEKV MDYIASECGV DSSDVVALVA PTNSPVGSVQ 

       190        200        210        220        230        240 
IAGRVVEMAI YKLAELGFDT RHIVSAFGSA PIPPVKKDAA VAMGTTNDAS IYHGSVTLTV 

       250        260        270        280        290        300 
DGGNIKDFVP KIPSSTSKDY GKPFYTVFKE AKFDFYKLDP GIFAPAEVVV NDISTGETYI 

       310 
AGKINADVCM ESFGFKKL 

« Hide

References

[1]"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere."
Erkel C., Kube M., Reinhardt R., Liesack W.
Science 313:370-372(2006) [PubMed: 16857943] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AM114193 Genomic DNA. Translation: CAJ35194.1.
RefSeqYP_684520.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5143584.
GenomeReviewsGene locus UNCMA_29790 in contig AM114193_GR.
KEGGrci:LRC191.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQ0W8U9. YFAMGSG.

Family and domain databases

HAMAPMF_00486.
[Tree]
InterProIPR003209. METHMP_CycHdrlase.
[Graphical view]
PfamPF02289. MCH. 1 hit.
[Graphical view]
ProDomPD011637. Cyclohydrolase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR03120. one_C_mch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMCH_UNCMA
AccessionPrimary (citable) accession number: Q0W8U9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents