Q0W723 (Q0W723_UNCMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-hydroxy-3-methylglutaryl-coenzyme A reductase EMBL CAJ35820.1
EC=1.1.1.34 EMBL CAJ35820.1

Gene names

Name:	hmgA EMBL CAJ35820.1
Ordered Locus Names:	UNCMA_23620
ORF Names:	RCIX376 EMBL CAJ35820.1

Organism

Uncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP] EMBL CAJ35820.1

Taxonomic identifier

351160 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › environmental samples

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269 EMBL CAJ35820.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0W723 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 2377D520CB23CD2D	FASTA	428	45,545
	10 20 30 40 50 60 MISMEKSSQI SGFYKLPPQE RLAKVKELAG LTDEEAAVIG ATGALKWEQV DRMVENVIGV 70 80 90 100 110 120 IPVPLGVAVN FRVNDKDYLV PMAIEEPSVI AAASNAAKMA REKGGFKTSS TGPVMRGLIQ 130 140 150 160 170 180 VTEVKDPFSA RLEVLAAKDK IMELANAVDP ILVKFGGGCK DVEAYVREVP NKPGHTMLIV 190 200 210 220 230 240 HLIVDCRDAM GANAVNTMTE TVGPHIEKIT GGKVYLRIIS NLADRRLMRA KAVFGKEAIG 250 260 270 280 290 300 GENVVDAVIK AYEFALADPY RAATHNKGIM NGISAVTLAT GNDTRAIEAG AHAYAAITGT 310 320 330 340 350 360 YRPLTTYEKN ADGDLVATIE LPLAVGLVGG ATASHPTAKA NVKILGVKTA TELGEVMAAV 370 380 390 400 410 420 GLAQNFAALR ALATEGIQRG HMQLHSRNVA IQAGATGDLI DRVAEAMVKE KKVRADRAKE LLEEFIKQ

References

[1]	"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere." Erkel C., Kube M., Reinhardt R., Liesack W. Science 313:370-372(2006) [PubMed: 16857943] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM114193 Genomic DNA. Translation: CAJ35820.1.
RefSeq	YP_685146.1. NC_009464.1.
3D structure databases
ProteinModelPortal	Q0W723.
SMR	Q0W723. Positions 7-428.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0W723.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5143649.
GenomeReviews	Gene locus UNCMA_23620 in contig AM114193_GR.
KEGG	rci:RCIX376.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04678.
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK2789729.
Enzyme and pathway databases
BioCyc	UMET351160:RCIX376-MONOMER.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
PANTHER	PTHR10572. HMG-CoA_red. 1 hit.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS00318. HMG_COA_REDUCTASE_2. 1 hit. PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0W723_UNCMA

Accession

Primary (citable) accession number: Q0W723

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	November 16, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)